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The map label for this gene is degQ [H]

Identifier: 194735465

GI number: 194735465

Start: 3413647

End: 3415002

Strand: Direct

Name: degQ [H]

Synonym: SeSA_A3540

Alternate gene names: 194735465

Gene position: 3413647-3415002 (Clockwise)

Preceding gene: 194735949

Following gene: 194734903

Centisome position: 72.49

GC content: 53.83

Gene sequence:

>1356_bases
ATGAAAAAACACACCCAGCTGTTAAGTGCATTAGCGTTAAGTGTCGGGTTAACTCTTTCGGCGCCGTTTCCAGCCCTTGC
ATCGATACCAGGCCAGGCGACGCTGCCAAGCCTTGCCCCTATGCTGGAGAAAGTGCTGCCTGCTGTCGTCAGCGTAAAAG
TCGAGGGAACCGCCGCCCAGAGCCAAAAAGTGCCGGAGGAGTTTAAAAAATTCTTTGGCGAGGATCTGCCAGACCAGCCG
TCCCAGCCGTTTGAAGGACTCGGTTCGGGGGTGATTATCGATGCCGCGAAAGGCTATGTATTAACCAATAATCATGTGAT
TAATCAGGCACAAAAGATCAGCATTCAACTGAATGACGGACGCGAATTCGACGCGAAGCTGATCGGCGGCGACGACCAGA
GCGATATCGCTCTGTTACAAATTCAGAATCCCAGCAAGTTAACGCAAATTGCCATCGCCGATTCCGACAAACTCCGCGTC
GGCGATTTCGCCGTGGCGGTCGGTAATCCGTTTGGTCTTGGACAAACCGCCACCTCCGGGATTATTTCAGCGCTGGGACG
CAGCGGGCTTAATCTGGAAGGGCTTGAGAACTTTATTCAAACCGATGCCTCTATTAACCGCGGCAACTCCGGCGGCGCGC
TGCTTAACCTGAACGGCGAGCTGATCGGGATTAATACCGCGATCCTCGCGCCAGGTGGCGGGAGTATCGGCATTGGCTTT
GCTATTCCTTCCAATATGGCGCAGACGCTGGCGCAGCAGTTGATTCAGTTCGGCGAAATCAAACGCGGATTGCTGGGAAT
TAAAGGCACTGAAATGACCGCTGATATCGCCAAGGCATTCAAACTGAACGTTCAGCGTGGCGCTTTTGTCAGCGAGGTTT
TACCCAATTCAGGTTCGGCGAAGGCCGGGGTGAAATCCGGAGACGTGATTATCAGTCTTAACGGTAAGCCGCTGAATAGC
TTTGCCGAACTGCGTTCACGTATCGCCACCACCGAACCGGGCACGAAAGTGAAGCTGGGCCTGCTGCGCGATGGTAAGCC
GCTGGAGGTGGAAGTCACGCTGGATTCCAATACCTCTTCTTCCGCCAGCGCCGAAATGATCGCCCCGGCGTTGCAAGGCG
CGACGTTGAGCGACGGCCAGCTGAAAGACGGGACGAAAGGCGTTAAGGTTGATAGCGTCGAAAAAAGCAGTCCTGCCGCG
CAGGCCGGTTTGCAAAAAGATGATGTTATCATCGGCGTTAACCGCGATCGTATCAGTTCTATCGCCGAAATGCGCAAAGT
GATGGCGGCAAAACCGTCCATCATTGCTCTTCAGGTAGTACGCGGCAACGAGAACATTTATCTATTGCTACGCTAA

Upstream 100 bases:

>100_bases
CCTGTCCCAGCTATTATCATTGTTACCAGGCTGAAAATTCAATAACATCAATCTGTTTTGAATTGTCTATCCGTTCATCC
AAGGTACGAGAGCAGCATCC

Downstream 100 bases:

>100_bases
TCCTGTCTTAAACCGGGCATCAGCCTGCGATGTGATGTCCGGTTAACTCATGGTATGCTGCTGCCGTTCCCTTTTTTAAC
GACGCCTCCATCATGTTTGT

Product: serine endoprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKKHTQLLSALALSVGLTLSAPFPALASIPGQATLPSLAPMLEKVLPAVVSVKVEGTAAQSQKVPEEFKKFFGEDLPDQP
SQPFEGLGSGVIIDAAKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGGDDQSDIALLQIQNPSKLTQIAIADSDKLRV
GDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSIGIGF
AIPSNMAQTLAQQLIQFGEIKRGLLGIKGTEMTADIAKAFKLNVQRGAFVSEVLPNSGSAKAGVKSGDVIISLNGKPLNS
FAELRSRIATTEPGTKVKLGLLRDGKPLEVEVTLDSNTSSSASAEMIAPALQGATLSDGQLKDGTKGVKVDSVEKSSPAA
QAGLQKDDVIIGVNRDRISSIAEMRKVMAAKPSIIALQVVRGNENIYLLLR

Sequences:

>Translated_451_residues
MKKHTQLLSALALSVGLTLSAPFPALASIPGQATLPSLAPMLEKVLPAVVSVKVEGTAAQSQKVPEEFKKFFGEDLPDQP
SQPFEGLGSGVIIDAAKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGGDDQSDIALLQIQNPSKLTQIAIADSDKLRV
GDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSIGIGF
AIPSNMAQTLAQQLIQFGEIKRGLLGIKGTEMTADIAKAFKLNVQRGAFVSEVLPNSGSAKAGVKSGDVIISLNGKPLNS
FAELRSRIATTEPGTKVKLGLLRDGKPLEVEVTLDSNTSSSASAEMIAPALQGATLSDGQLKDGTKGVKVDSVEKSSPAA
QAGLQKDDVIIGVNRDRISSIAEMRKVMAAKPSIIALQVVRGNENIYLLLR
>Mature_451_residues
MKKHTQLLSALALSVGLTLSAPFPALASIPGQATLPSLAPMLEKVLPAVVSVKVEGTAAQSQKVPEEFKKFFGEDLPDQP
SQPFEGLGSGVIIDAAKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGGDDQSDIALLQIQNPSKLTQIAIADSDKLRV
GDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSIGIGF
AIPSNMAQTLAQQLIQFGEIKRGLLGIKGTEMTADIAKAFKLNVQRGAFVSEVLPNSGSAKAGVKSGDVIISLNGKPLNS
FAELRSRIATTEPGTKVKLGLLRDGKPLEVEVTLDSNTSSSASAEMIAPALQGATLSDGQLKDGTKGVKVDSVEKSSPAA
QAGLQKDDVIIGVNRDRISSIAEMRKVMAAKPSIIALQVVRGNENIYLLLR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=316, Percent_Identity=36.0759493670886, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI4506141, Length=294, Percent_Identity=36.3945578231293, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI24308541, Length=302, Percent_Identity=30.1324503311258, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI7019477, Length=296, Percent_Identity=32.7702702702703, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1789629, Length=455, Percent_Identity=89.6703296703297, Blast_Score=794, Evalue=0.0,
Organism=Escherichia coli, GI1786356, Length=457, Percent_Identity=56.2363238512035, Blast_Score=503, Evalue=1e-144,
Organism=Escherichia coli, GI1789630, Length=357, Percent_Identity=39.4957983193277, Blast_Score=214, Evalue=9e-57,
Organism=Drosophila melanogaster, GI24646839, Length=288, Percent_Identity=32.2916666666667, Blast_Score=123, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 46899; Mature: 46899

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHTQLLSALALSVGLTLSAPFPALASIPGQATLPSLAPMLEKVLPAVVSVKVEGTAAQ
CCHHHHHHHHHHHHHCCEECCCCCHHHCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCHH
SQKVPEEFKKFFGEDLPDQPSQPFEGLGSGVIIDAAKGYVLTNNHVINQAQKISIQLNDG
HHCCHHHHHHHHCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCCEECCEEEEEEEECCC
REFDAKLIGGDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSG
CCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCEEECEEEEEECCCCCCCHHHHHH
IISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSIGIGF
HHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCCEEEEE
AIPSNMAQTLAQQLIQFGEIKRGLLGIKGTEMTADIAKAFKLNVQRGAFVSEVLPNSGSA
ECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCC
KAGVKSGDVIISLNGKPLNSFAELRSRIATTEPGTKVKLGLLRDGKPLEVEVTLDSNTSS
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEECCCCCC
SASAEMIAPALQGATLSDGQLKDGTKGVKVDSVEKSSPAAQAGLQKDDVIIGVNRDRISS
CCCHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCHHHCCCCCCCEEEECCHHHHHH
IAEMRKVMAAKPSIIALQVVRGNENIYLLLR
HHHHHHHHHCCCCEEEEEEEECCCCEEEEEC
>Mature Secondary Structure
MKKHTQLLSALALSVGLTLSAPFPALASIPGQATLPSLAPMLEKVLPAVVSVKVEGTAAQ
CCHHHHHHHHHHHHHCCEECCCCCHHHCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCHH
SQKVPEEFKKFFGEDLPDQPSQPFEGLGSGVIIDAAKGYVLTNNHVINQAQKISIQLNDG
HHCCHHHHHHHHCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCCEECCEEEEEEEECCC
REFDAKLIGGDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSG
CCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCEEECEEEEEECCCCCCCHHHHHH
IISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSIGIGF
HHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCCEEEEE
AIPSNMAQTLAQQLIQFGEIKRGLLGIKGTEMTADIAKAFKLNVQRGAFVSEVLPNSGSA
ECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCC
KAGVKSGDVIISLNGKPLNSFAELRSRIATTEPGTKVKLGLLRDGKPLEVEVTLDSNTSS
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEECCCCCC
SASAEMIAPALQGATLSDGQLKDGTKGVKVDSVEKSSPAAQAGLQKDDVIIGVNRDRISS
CCCHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCHHHCCCCCCCEEEECCHHHHHH
IAEMRKVMAAKPSIIALQVVRGNENIYLLLR
HHHHHHHHHCCCCEEEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]