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The map label for this gene is trpR

Identifier: 194735421

GI number: 194735421

Start: 4692672

End: 4692998

Strand: Direct

Name: trpR

Synonym: SeSA_A4834

Alternate gene names: 194735421

Gene position: 4692672-4692998 (Clockwise)

Preceding gene: 194734270

Following gene: 194737068

Centisome position: 99.65

GC content: 55.05

Gene sequence:

>327_bases
ATGACCCAGCATTCCCCTTATTCATCGGCTATCGCCGAACAACGTAATCAGGAGTGGCTTCGTTTTGTGGAGTTACTCCG
TCAGGCATATGCAGAGGATCTGCATCTGCCTTTATTACAACTGATGCTTACGCCGGACGAGCGTGAAGCGCTGGGAACGC
GCGTGCGCATTATTGAGGAGTTGCTGCGTGGCGAAATGAGCCAGCGCGAGTTGAAAACCGAGCTGGGGGCGGGCATCGCC
ACCATCACGCGCGGGTCAAACAGCCTGAAATCCGCGCCGGTTGAACTGCGTCATTGGCTTGAGAATGTACTGCTGAAAAA
CGCCTGA

Upstream 100 bases:

>100_bases
AGAGGCCTTAATGAGCGACTCTGAGTGGCAGCGGCGGTATTAATGCAGACGGGTTATGTTATCATTTGTACTCGTGTAAC
AGTACAAACGGCGGTATAAC

Downstream 100 bases:

>100_bases
TTTGCTCGTAGGCCGGATAAGGCGAAGCGGCCATCCGGCGACATCGCCGCGAAATGCCTGATGGCGCTGTGCTTATCAGG
CCTACAACATAGCGCAAATA

Product: Trp operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MTQHSPYSSAIAEQRNQEWLRFVELLRQAYAEDLHLPLLQLMLTPDEREALGTRVRIIEELLRGEMSQRELKTELGAGIA
TITRGSNSLKSAPVELRHWLENVLLKNA

Sequences:

>Translated_108_residues
MTQHSPYSSAIAEQRNQEWLRFVELLRQAYAEDLHLPLLQLMLTPDEREALGTRVRIIEELLRGEMSQRELKTELGAGIA
TITRGSNSLKSAPVELRHWLENVLLKNA
>Mature_107_residues
TQHSPYSSAIAEQRNQEWLRFVELLRQAYAEDLHLPLLQLMLTPDEREALGTRVRIIEELLRGEMSQRELKTELGAGIAT
ITRGSNSLKSAPVELRHWLENVLLKNA

Specific function: This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regula

COG id: COG2973

COG function: function code K; Trp operon repressor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpR family

Homologues:

Organism=Escherichia coli, GI1790854, Length=107, Percent_Identity=84.1121495327103, Blast_Score=164, Evalue=1e-42,

Paralogues:

None

Copy number: 250-750 50-300 [C]

Swissprot (AC and ID): TRPR_SALDC (B5FTD7)

Other databases:

- EMBL:   CP001144
- RefSeq:   YP_002218454.1
- ProteinModelPortal:   B5FTD7
- SMR:   B5FTD7
- PRIDE:   B5FTD7
- GeneID:   6871871
- GenomeReviews:   CP001144_GR
- KEGG:   sed:SeD_A4995
- HOGENOM:   HBG677773
- OMA:   ELMRGEM
- ProtClustDB:   PRK01381
- GO:   GO:0005737
- HAMAP:   MF_00475
- InterPro:   IPR000831
- InterPro:   IPR013335
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1270.10
- PIRSF:   PIRSF003196
- ProDom:   PD012582
- TIGRFAMs:   TIGR01321

Pfam domain/function: PF01371 Trp_repressor; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 12391; Mature: 12260

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQHSPYSSAIAEQRNQEWLRFVELLRQAYAEDLHLPLLQLMLTPDEREALGTRVRIIEE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LLRGEMSQRELKTELGAGIATITRGSNSLKSAPVELRHWLENVLLKNA
HHHCHHHHHHHHHHHCCCHHHHHCCCCHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQHSPYSSAIAEQRNQEWLRFVELLRQAYAEDLHLPLLQLMLTPDEREALGTRVRIIEE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LLRGEMSQRELKTELGAGIATITRGSNSLKSAPVELRHWLENVLLKNA
HHHCHHHHHHHHHHHCCCHHHHHCCCCHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA