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The map label for this gene is mmgC [H]

Identifier: 194735419

GI number: 194735419

Start: 981850

End: 983013

Strand: Direct

Name: mmgC [H]

Synonym: SeSA_A1009

Alternate gene names: 194735419

Gene position: 981850-983013 (Clockwise)

Preceding gene: 194735942

Following gene: 194737505

Centisome position: 20.85

GC content: 43.13

Gene sequence:

>1164_bases
ATGAAAAGTATTGAAAAGGATAAATATCAGGATATTCGTGATGCGGTTCGTTCATTATGTAGTGAATTTGATGATAAATA
TCACCGTAAGATAGATGAAGCAAAAGCCTATCCTGAAGAGTTTGTTAATAAACTAACCAAAGCTGGTTGGCTGGCTGCGC
TCATCCCGGAGGAATTTGGAGGGTCAGGGCTTGGTTTAACTGAAGCATCTATTATCATGGAAGAGATCAATAGATCGGGT
GGAAACTCTGGAGCCTGCCATGGTCAGATGTATAACATGAATACGTTGTTACGTCATGGATCCGATAAACAGAAAGAATT
CTGGCTGCCACGGATAGCTACTGGTGAATGGCGCCTGCAGTCGATGGGCGTCACAGAACCCACAGCAGGTACAGATACCA
CCAGAATTAAAACTACAGCTGTAAAAAGAGAAGACCGGTATGTGATAAACGGACAAAAAGTCTGGATTTCACGTGTTCAA
CATTCAGACTGGATGATTCTTCTGGTTCGAACTACTCCGCTTGCAAATGTAAAACGTAAATCCGAAGGGATGTCTATTTT
CATGGTTGATATTAAAGAAGCTATGAAAAATGGAATGACAGTACGACCTATTCCCAATATGGTCAATCATGAAACCAACG
AGCTCTTTTTTGACAACCTGGAAATTCCCGAAGAAAATCTTATTGGTGAAGAGGGTATGGGTTTTCATTACATACTTGAT
GGTTTAAATGCAGAGCGTACCTTGATTGCGGCAGAATGTATAGGCGATGGATATTGGTTTATGGATCGTGTTACCCGCTA
TACCTGCGAGCGTGAGGTTTTTGGTCGTCCCATTGGTCAGAACCAGGGGGTGCAGTTTCCTATTGCAGAAGCATTTATTG
CAGTGGAAGCGGCTAATCTGATGCGTTTTAAAGCGTGCGAGCTTTTTGATCAGCATCTTGATTGTGGAGCACAGGCTAAT
ATGGCGAAATACCTTGCTGCGAAAGCCAGCTGGGAAGCAGCCAATGCCTGCCTGCAATTTCATGGTGGATATGGTTTTGC
CTGTGAGTATGATATCGAACGAAAGTTTAGAGAAACACGTTTATATCAGGTTGCTCCCATATCTACCAACCTGATCCTGA
GCTATATCGCTGAGCATGTGCTGGAGATGCCACGTTCATTCTGA

Upstream 100 bases:

>100_bases
TTCTTCCTGTCGACCGCCAGTCAGATCTATCTGCTGATGGTCATCCGATAAAAGGTCATTTTCTACCCCCTGTTGGCGCT
GGTTTATTGAGGAAAAAATT

Downstream 100 bases:

>100_bases
TGTCAAATCAATTGGAAAAATATTATGAAACAGTTACCTCTGTCCGGAGTCATTATAGTCTCGATTGAACATGTCATTGC
CACTCCCTTCTGTACCCGAC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKSIEKDKYQDIRDAVRSLCSEFDDKYHRKIDEAKAYPEEFVNKLTKAGWLAALIPEEFGGSGLGLTEASIIMEEINRSG
GNSGACHGQMYNMNTLLRHGSDKQKEFWLPRIATGEWRLQSMGVTEPTAGTDTTRIKTTAVKREDRYVINGQKVWISRVQ
HSDWMILLVRTTPLANVKRKSEGMSIFMVDIKEAMKNGMTVRPIPNMVNHETNELFFDNLEIPEENLIGEEGMGFHYILD
GLNAERTLIAAECIGDGYWFMDRVTRYTCEREVFGRPIGQNQGVQFPIAEAFIAVEAANLMRFKACELFDQHLDCGAQAN
MAKYLAAKASWEAANACLQFHGGYGFACEYDIERKFRETRLYQVAPISTNLILSYIAEHVLEMPRSF

Sequences:

>Translated_387_residues
MKSIEKDKYQDIRDAVRSLCSEFDDKYHRKIDEAKAYPEEFVNKLTKAGWLAALIPEEFGGSGLGLTEASIIMEEINRSG
GNSGACHGQMYNMNTLLRHGSDKQKEFWLPRIATGEWRLQSMGVTEPTAGTDTTRIKTTAVKREDRYVINGQKVWISRVQ
HSDWMILLVRTTPLANVKRKSEGMSIFMVDIKEAMKNGMTVRPIPNMVNHETNELFFDNLEIPEENLIGEEGMGFHYILD
GLNAERTLIAAECIGDGYWFMDRVTRYTCEREVFGRPIGQNQGVQFPIAEAFIAVEAANLMRFKACELFDQHLDCGAQAN
MAKYLAAKASWEAANACLQFHGGYGFACEYDIERKFRETRLYQVAPISTNLILSYIAEHVLEMPRSF
>Mature_387_residues
MKSIEKDKYQDIRDAVRSLCSEFDDKYHRKIDEAKAYPEEFVNKLTKAGWLAALIPEEFGGSGLGLTEASIIMEEINRSG
GNSGACHGQMYNMNTLLRHGSDKQKEFWLPRIATGEWRLQSMGVTEPTAGTDTTRIKTTAVKREDRYVINGQKVWISRVQ
HSDWMILLVRTTPLANVKRKSEGMSIFMVDIKEAMKNGMTVRPIPNMVNHETNELFFDNLEIPEENLIGEEGMGFHYILD
GLNAERTLIAAECIGDGYWFMDRVTRYTCEREVFGRPIGQNQGVQFPIAEAFIAVEAANLMRFKACELFDQHLDCGAQAN
MAKYLAAKASWEAANACLQFHGGYGFACEYDIERKFRETRLYQVAPISTNLILSYIAEHVLEMPRSF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=379, Percent_Identity=28.2321899736148, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI4557233, Length=377, Percent_Identity=28.3819628647215, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI187960098, Length=354, Percent_Identity=30.7909604519774, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI4557231, Length=354, Percent_Identity=30.7909604519774, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI226958414, Length=334, Percent_Identity=31.437125748503, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI226958412, Length=368, Percent_Identity=29.6195652173913, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI4501857, Length=390, Percent_Identity=29.4871794871795, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI7656849, Length=361, Percent_Identity=28.5318559556787, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI21361497, Length=356, Percent_Identity=27.8089887640449, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI4557235, Length=385, Percent_Identity=25.974025974026, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=25.974025974026, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI7669494, Length=351, Percent_Identity=23.6467236467236, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4503943, Length=351, Percent_Identity=23.6467236467236, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38505218, Length=336, Percent_Identity=27.0833333333333, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI211971008, Length=318, Percent_Identity=24.5283018867925, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI48976061, Length=318, Percent_Identity=24.5283018867925, Blast_Score=85, Evalue=9e-17,
Organism=Escherichia coli, GI87081958, Length=367, Percent_Identity=28.0653950953678, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786223, Length=369, Percent_Identity=27.3712737127371, Blast_Score=144, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17534899, Length=342, Percent_Identity=33.6257309941521, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17570075, Length=356, Percent_Identity=31.4606741573034, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17569725, Length=361, Percent_Identity=30.1939058171745, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17538396, Length=366, Percent_Identity=29.2349726775956, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=26.8817204301075, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17508101, Length=375, Percent_Identity=26.6666666666667, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71985184, Length=356, Percent_Identity=28.0898876404494, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17533517, Length=354, Percent_Identity=29.9435028248588, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71990804, Length=303, Percent_Identity=30.03300330033, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17505929, Length=335, Percent_Identity=29.5522388059701, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17551932, Length=333, Percent_Identity=28.8288288288288, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71985192, Length=268, Percent_Identity=29.8507462686567, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI32563615, Length=245, Percent_Identity=29.3877551020408, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17534353, Length=350, Percent_Identity=25.1428571428571, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17562446, Length=302, Percent_Identity=25.1655629139073, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=260, Percent_Identity=23.8461538461538, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21356377, Length=359, Percent_Identity=30.9192200557103, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24666513, Length=388, Percent_Identity=28.8659793814433, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24660351, Length=367, Percent_Identity=30.2452316076294, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI21355753, Length=338, Percent_Identity=28.9940828402367, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24646207, Length=380, Percent_Identity=26.8421052631579, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI281363737, Length=400, Percent_Identity=25.75, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19920834, Length=354, Percent_Identity=24.8587570621469, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43992; Mature: 43992

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIEKDKYQDIRDAVRSLCSEFDDKYHRKIDEAKAYPEEFVNKLTKAGWLAALIPEEFG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECHHHCC
GSGLGLTEASIIMEEINRSGGNSGACHGQMYNMNTLLRHGSDKQKEFWLPRIATGEWRLQ
CCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHCCCCCCHHCCCCCCCCCCEEEE
SMGVTEPTAGTDTTRIKTTAVKREDRYVINGQKVWISRVQHSDWMILLVRTTPLANVKRK
ECCCCCCCCCCCCCEEEEEEECCCCCEEECCCEEEEEEECCCCEEEEEEECCCCHHHHHH
SEGMSIFMVDIKEAMKNGMTVRPIPNMVNHETNELFFDNLEIPEENLIGEEGMGFHYILD
CCCCEEEEEEHHHHHHCCCEECCCCHHHCCCCCCEEECCCCCCHHHCCCCCCCCCEEEEC
GLNAERTLIAAECIGDGYWFMDRVTRYTCEREVFGRPIGQNQGVQFPIAEAFIAVEAANL
CCCCCHHEEEEHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
MRFKACELFDQHLDCGAQANMAKYLAAKASWEAANACLQFHGGYGFACEYDIERKFRETR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHEECCCCCEEEEECHHHHHHHHH
LYQVAPISTNLILSYIAEHVLEMPRSF
CEEEECCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKSIEKDKYQDIRDAVRSLCSEFDDKYHRKIDEAKAYPEEFVNKLTKAGWLAALIPEEFG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECHHHCC
GSGLGLTEASIIMEEINRSGGNSGACHGQMYNMNTLLRHGSDKQKEFWLPRIATGEWRLQ
CCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHCCCCCCHHCCCCCCCCCCEEEE
SMGVTEPTAGTDTTRIKTTAVKREDRYVINGQKVWISRVQHSDWMILLVRTTPLANVKRK
ECCCCCCCCCCCCCEEEEEEECCCCCEEECCCEEEEEEECCCCEEEEEEECCCCHHHHHH
SEGMSIFMVDIKEAMKNGMTVRPIPNMVNHETNELFFDNLEIPEENLIGEEGMGFHYILD
CCCCEEEEEEHHHHHHCCCEECCCCHHHCCCCCCEEECCCCCCHHHCCCCCCCCCEEEEC
GLNAERTLIAAECIGDGYWFMDRVTRYTCEREVFGRPIGQNQGVQFPIAEAFIAVEAANL
CCCCCHHEEEEHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
MRFKACELFDQHLDCGAQANMAKYLAAKASWEAANACLQFHGGYGFACEYDIERKFRETR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHEECCCCCEEEEECHHHHHHHHH
LYQVAPISTNLILSYIAEHVLEMPRSF
CEEEECCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]