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The map label for this gene is arsC [H]

Identifier: 194735384

GI number: 194735384

Start: 694880

End: 695305

Strand: Direct

Name: arsC [H]

Synonym: SeSA_A0718

Alternate gene names: 194735384

Gene position: 694880-695305 (Clockwise)

Preceding gene: 194736038

Following gene: 194737010

Centisome position: 14.76

GC content: 46.01

Gene sequence:

>426_bases
ATGAGCAACATTACCATCTATCACAACCCTGCCTGCGGCACTTCTCGCAATACGCTGGAGATGATCCGTAACAGCGGCAA
CGAACCGACGATAATTTATTATCTCAATACGCCACCGACCCGTGATGAGCTGATTAAACTTATTTCAGATATGGGAATTA
CGGTGCGTGCATTACTGCGTAAGAATGTTGAGCCTTATGAACACCTGGGGCTTGGTAAAGAGAAATTTAGTGATGAACAG
TTGATTGATTTCATGCTTCAACATCCGATCCTGATTAATCGGCCGGTAGTCGTTACGCCGCTTGGCACTCGTCTTTGCCG
CCCTTCAGAAATAGTATTGGATATTCTACCGGAAGGTCAGAAAGGAGCGTTTACCAAAGAGGATGGCGAGAAGGTTATTG
ACGAAACGGGGAAGCGGGTTAAGTAA

Upstream 100 bases:

>100_bases
TTACTTCCGCACCGGCATTATCATGACTCTGCCCGTGCTGTTTGTCACTTTGGCCGCGCTGGCGTTGCGGCTCTCCATCA
CTTTGTAATGAGATACAGAT

Downstream 100 bases:

>100_bases
TCTGCCCACTTCAAAATATCGGACGCCTGTTAACGTTATGCGGGCGTCCGCTTCTCGCTCAGAGCGGACGGTCAGACTCG
ATTGCATTCTGTCTGCGGAA

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MSNITIYHNPACGTSRNTLEMIRNSGNEPTIIYYLNTPPTRDELIKLISDMGITVRALLRKNVEPYEHLGLGKEKFSDEQ
LIDFMLQHPILINRPVVVTPLGTRLCRPSEIVLDILPEGQKGAFTKEDGEKVIDETGKRVK

Sequences:

>Translated_141_residues
MSNITIYHNPACGTSRNTLEMIRNSGNEPTIIYYLNTPPTRDELIKLISDMGITVRALLRKNVEPYEHLGLGKEKFSDEQ
LIDFMLQHPILINRPVVVTPLGTRLCRPSEIVLDILPEGQKGAFTKEDGEKVIDETGKRVK
>Mature_140_residues
SNITIYHNPACGTSRNTLEMIRNSGNEPTIIYYLNTPPTRDELIKLISDMGITVRALLRKNVEPYEHLGLGKEKFSDEQL
IDFMLQHPILINRPVVVTPLGTRLCRPSEIVLDILPEGQKGAFTKEDGEKVIDETGKRVK

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=141, Percent_Identity=84.3971631205674, Blast_Score=258, Evalue=1e-70,
Organism=Escherichia coli, GI1788841, Length=115, Percent_Identity=38.2608695652174, Blast_Score=87, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 15931; Mature: 15800

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNITIYHNPACGTSRNTLEMIRNSGNEPTIIYYLNTPPTRDELIKLISDMGITVRALLR
CCCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHH
KNVEPYEHLGLGKEKFSDEQLIDFMLQHPILINRPVVVTPLGTRLCRPSEIVLDILPEGQ
CCCCHHHHHCCCHHHCCHHHHHHHHHHCCEEECCCEEEEECCCHHCCCCHHEEEECCCCC
KGAFTKEDGEKVIDETGKRVK
CCCCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
SNITIYHNPACGTSRNTLEMIRNSGNEPTIIYYLNTPPTRDELIKLISDMGITVRALLR
CCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHH
KNVEPYEHLGLGKEKFSDEQLIDFMLQHPILINRPVVVTPLGTRLCRPSEIVLDILPEGQ
CCCCHHHHHCCCHHHCCHHHHHHHHHHCCEEECCCEEEEECCCHHCCCCHHEEEECCCCC
KGAFTKEDGEKVIDETGKRVK
CCCCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]