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The map label for this gene is nupG [H]

Identifier: 194735371

GI number: 194735371

Start: 2536383

End: 2537639

Strand: Reverse

Name: nupG [H]

Synonym: SeSA_A2656

Alternate gene names: 194735371

Gene position: 2537639-2536383 (Counterclockwise)

Preceding gene: 194735023

Following gene: 194736044

Centisome position: 53.89

GC content: 48.53

Gene sequence:

>1257_bases
ATGGGTATTACGTCCCGCTTAAAAGTCATGTCGTTCTTGCAATATTTTATCTGGGGGAGCTGGCTGGTTACCCTGGGCTC
TTACATGATCAATACACTGGATTTTACCGGCGCGAATGTCGGTATGGTCTACAGCTCAAAAGGACTGGCAGCGATTATCA
TGCCGGGCATTATGGGGATCATTGCTGATAAATGGCTGCGCGCTGAACGAGCCTATATGCTTTGCCATCTGGTTTGCGCG
GGGGCGTTATTGTACGCCACCACCGTTACCGATCCCCAGACGATGTTCTGGGTGATGTTGGTTAATGCGATGGCGTATAT
GCCAACGATTGCATTATCCAATAGCGTTTCGTACTCCTGTCTGGCGAAAGCAGGTCAGGATCCGGTAACGTCATTTCCGC
CTGTGCGCGTTTTCGGCACAATAGGTTTTATTGTTGCGATGTGGACGGTGAGCCTGATGGGGCTGGAACTGAGCAGTGCG
CAATTATACATCGCTTCTGGCGCATCGTTATTGCTGGCCCTGTATGCACTGACGTTACCGAAAATTCCGGTAGCCGAGAA
GAAGGCGAACACCACGCTTGCCAGTAAGCTCGGACTGGATGCTTTTGTTCTGTTTAAAAATCCACGCATGGCAATCTTCT
TTTTGTTTGCGATGATGTTGGGGGCGGTGCTGCAAATTACCAATGTCTTCGGTAATCCGTTCCTGCATGATTTTGCCCGA
AATCCTGAGTTTGCCGATAGTTTTGTGGTGAAGTATCCCTCTATCTTGCTTTCAGTTTCGCAGATGGCGGAAGTGGGCTT
TATCCTCATCATTCCGTTCTTCCTTAAACGCTTTGGTATTAAAACGGTAATGCTGATGAGCATGCTGGCATGGACGCTGC
GTTTCGGCTTCTTTGCCTTTGGCGATCCATCCCCGTTTGGCTTTGTGCTATTGCTGCTGTCGATGATTGTTTATGGCTGC
GCATTTGATTTCTTCAACATCTCAGGGCCGGTATTTGTAGAGCAGGAAGTGGACTCAAGTATTCGCGCCAGCGCGCAGGG
GCTGTTTATGACCATGGTTAACGGCGTGGGGGCGTGGATTGGGTCTCTTTTAAGTGGTATGGCCGTGGATTATTTTTCTA
TTGATGGTGTAAAAGATTGGCAAACCATCTGGCTGGTCTTTGCCGCCTACGCTCTGGCATTGGCCGTTATTTTTGCATTG
TTCTTTAAATATCAGCACCATCCAGAAAAACTGTCGACCAAATCATTAGCACATTAA

Upstream 100 bases:

>100_bases
GAACTTTATAAATCTGATTTGCGGCTTTTTACGTAAGCTGGACTAAACACAATGACTACGGCCCCGTATTGGGGCTTTAT
CTCACGGCAAGGAATAAAAA

Downstream 100 bases:

>100_bases
TTTTATTTGACTGGCGAGAGGATGTTCGCCAGTCCATTTTTATGAACAAGGACACAGCATGAAAGAAATTATTCTCTCCT
CCGGTATTGGATTTGGTATT

Product: nucleoside permease NupG

Products: Proton [Cytoplasm]; xanthosine [Cytoplasm] [C]

Alternate protein names: Xanthosine transporter [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MGITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVYSSKGLAAIIMPGIMGIIADKWLRAERAYMLCHLVCA
GALLYATTVTDPQTMFWVMLVNAMAYMPTIALSNSVSYSCLAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSA
QLYIASGASLLLALYALTLPKIPVAEKKANTTLASKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
NPEFADSFVVKYPSILLSVSQMAEVGFILIIPFFLKRFGIKTVMLMSMLAWTLRFGFFAFGDPSPFGFVLLLLSMIVYGC
AFDFFNISGPVFVEQEVDSSIRASAQGLFMTMVNGVGAWIGSLLSGMAVDYFSIDGVKDWQTIWLVFAAYALALAVIFAL
FFKYQHHPEKLSTKSLAH

Sequences:

>Translated_418_residues
MGITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVYSSKGLAAIIMPGIMGIIADKWLRAERAYMLCHLVCA
GALLYATTVTDPQTMFWVMLVNAMAYMPTIALSNSVSYSCLAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSA
QLYIASGASLLLALYALTLPKIPVAEKKANTTLASKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
NPEFADSFVVKYPSILLSVSQMAEVGFILIIPFFLKRFGIKTVMLMSMLAWTLRFGFFAFGDPSPFGFVLLLLSMIVYGC
AFDFFNISGPVFVEQEVDSSIRASAQGLFMTMVNGVGAWIGSLLSGMAVDYFSIDGVKDWQTIWLVFAAYALALAVIFAL
FFKYQHHPEKLSTKSLAH
>Mature_417_residues
GITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVYSSKGLAAIIMPGIMGIIADKWLRAERAYMLCHLVCAG
ALLYATTVTDPQTMFWVMLVNAMAYMPTIALSNSVSYSCLAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSAQ
LYIASGASLLLALYALTLPKIPVAEKKANTTLASKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFARN
PEFADSFVVKYPSILLSVSQMAEVGFILIIPFFLKRFGIKTVMLMSMLAWTLRFGFFAFGDPSPFGFVLLLLSMIVYGCA
FDFFNISGPVFVEQEVDSSIRASAQGLFMTMVNGVGAWIGSLLSGMAVDYFSIDGVKDWQTIWLVFAAYALALAVIFALF
FKYQHHPEKLSTKSLAH

Specific function: Nucleoside transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli nupG and yegT [H]

Homologues:

Organism=Escherichia coli, GI1788745, Length=418, Percent_Identity=88.2775119617225, Blast_Score=711, Evalue=0.0,
Organism=Escherichia coli, GI87082192, Length=418, Percent_Identity=57.6555023923445, Blast_Score=495, Evalue=1e-141,
Organism=Escherichia coli, GI1788415, Length=423, Percent_Identity=29.5508274231678, Blast_Score=189, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR004740 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45990; Mature: 45859

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVYSSKGLAAIIMPGIMGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
IADKWLRAERAYMLCHLVCAGALLYATTVTDPQTMFWVMLVNAMAYMPTIALSNSVSYSC
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSAQLYIASGASLLLALYALTLP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCCEEEEECCHHHHHHHHHHHCC
KIPVAEKKANTTLASKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
CCCCCCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
NPEFADSFVVKYPSILLSVSQMAEVGFILIIPFFLKRFGIKTVMLMSMLAWTLRFGFFAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDPSPFGFVLLLLSMIVYGCAFDFFNISGPVFVEQEVDSSIRASAQGLFMTMVNGVGAWI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCHHHHHHHHHHHHHHHHHHHHHH
GSLLSGMAVDYFSIDGVKDWQTIWLVFAAYALALAVIFALFFKYQHHPEKLSTKSLAH
HHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHCCC
>Mature Secondary Structure 
GITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVYSSKGLAAIIMPGIMGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
IADKWLRAERAYMLCHLVCAGALLYATTVTDPQTMFWVMLVNAMAYMPTIALSNSVSYSC
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSAQLYIASGASLLLALYALTLP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCCEEEEECCHHHHHHHHHHHCC
KIPVAEKKANTTLASKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
CCCCCCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
NPEFADSFVVKYPSILLSVSQMAEVGFILIIPFFLKRFGIKTVMLMSMLAWTLRFGFFAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDPSPFGFVLLLLSMIVYGCAFDFFNISGPVFVEQEVDSSIRASAQGLFMTMVNGVGAWI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCHHHHHHHHHHHHHHHHHHHHHH
GSLLSGMAVDYFSIDGVKDWQTIWLVFAAYALALAVIFALFFKYQHHPEKLSTKSLAH
HHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; xanthosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + xanthosine [Periplasm] = Proton [Cytoplasm] + xanthosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7559336; 9205837; 9278503 [H]