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The map label for this gene is ttdA [H]

Identifier: 194735312

GI number: 194735312

Start: 3421065

End: 3421964

Strand: Reverse

Name: ttdA [H]

Synonym: SeSA_A3547

Alternate gene names: 194735312

Gene position: 3421964-3421065 (Counterclockwise)

Preceding gene: 194735885

Following gene: 194735860

Centisome position: 72.67

GC content: 52.11

Gene sequence:

>900_bases
ATGAGCAAAAGTGAACAGATATCCCATATGACCGACGTTATGGCCAAGTTTGTGGGATATACCGGCAAAGTTTTGCCTGA
TGATGTCACTGCAAAACTGGAAGATTTGCATAAGAAAGAGACCAGTAAACTGGCCGACGTCATCTTTACTACCATGATTG
AGAACCAGCGTCTGGCGAAAGAGCTGGATCGACCTTCCTGCCAGGACACCGGTGTCATTCAGTTTCTGGTGGAGTGCGGG
ACGAACTTTCCGCTGATTGGCGAGCTGGAAGCGTTGTTGCGTGAGGCGGTGATCAAAGCAACTGTAGATTCTCCGCTGCG
CCACAACAGCGTAGAAACTTTTGATGAATACAACACCGGTAAAAACGTGGGTAAAGGTACGCCGACGGTCTTCTGGGAGA
TCGTTCCCAACTCCGATCAGTGCAGCATTTATACCTATATGGCGGGCGGTGGTTGTTCTCTGCCGGGGAAAGCGATGGTG
CTGATGCCGGGTGCAGGCTATGAAGGTGTGACCCGCTTTGTACTGGATGTGATGACCAGCTACGGCCTCAACGCTTGTCC
GCCGCTGCTGGTTGGCGTGGGCGTAGCGACCTCTGTTGAAACGGCGGCACTGCTATCGAAAAAAGCGCTGATGCGTCCGA
TCGGTTCGCATAACGAGAATGAGCGTGCAGCCTCGCTGGAAAAAATGCTGGAAGACGGCATTAACAAAATTGGCCTGGGG
CCGCAGGGGATGTCCGGTAATACCTCCGTTATGGGCGTGAACATTGAAAACACCGCGCGTCATCCTTCTACCATCGGCGT
AGCGGTAAACGTCGGCTGCTGGTCGCACCGTAAAGGGCACATCGTTTTCGATAAAGATTTGAATTACACCATTACGTCTC
ACAGCGGAGTGAATTTCTGA

Upstream 100 bases:

>100_bases
CCCTGATTATCGTTTCAACCATTGTCAGCTTGATCCTGCTGCCAATCCTTTTCCCTTTTCATCCGTAATTAACGGAAGCT
GTTCTGACTAAGGAGCATTT

Downstream 100 bases:

>100_bases
TGACTAAAAAAATCCTGACTACGCCAATTAAAGATGAAGATTTAGCGGATATTAAGGCTGGCGATATTATTTATCTCAAC
GGTCATATTGTTACCTGCCG

Product: tartrate dehydratase subunit alpha

Products: NA

Alternate protein names: L-TTD alpha [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSKSEQISHMTDVMAKFVGYTGKVLPDDVTAKLEDLHKKETSKLADVIFTTMIENQRLAKELDRPSCQDTGVIQFLVECG
TNFPLIGELEALLREAVIKATVDSPLRHNSVETFDEYNTGKNVGKGTPTVFWEIVPNSDQCSIYTYMAGGGCSLPGKAMV
LMPGAGYEGVTRFVLDVMTSYGLNACPPLLVGVGVATSVETAALLSKKALMRPIGSHNENERAASLEKMLEDGINKIGLG
PQGMSGNTSVMGVNIENTARHPSTIGVAVNVGCWSHRKGHIVFDKDLNYTITSHSGVNF

Sequences:

>Translated_299_residues
MSKSEQISHMTDVMAKFVGYTGKVLPDDVTAKLEDLHKKETSKLADVIFTTMIENQRLAKELDRPSCQDTGVIQFLVECG
TNFPLIGELEALLREAVIKATVDSPLRHNSVETFDEYNTGKNVGKGTPTVFWEIVPNSDQCSIYTYMAGGGCSLPGKAMV
LMPGAGYEGVTRFVLDVMTSYGLNACPPLLVGVGVATSVETAALLSKKALMRPIGSHNENERAASLEKMLEDGINKIGLG
PQGMSGNTSVMGVNIENTARHPSTIGVAVNVGCWSHRKGHIVFDKDLNYTITSHSGVNF
>Mature_298_residues
SKSEQISHMTDVMAKFVGYTGKVLPDDVTAKLEDLHKKETSKLADVIFTTMIENQRLAKELDRPSCQDTGVIQFLVECGT
NFPLIGELEALLREAVIKATVDSPLRHNSVETFDEYNTGKNVGKGTPTVFWEIVPNSDQCSIYTYMAGGGCSLPGKAMVL
MPGAGYEGVTRFVLDVMTSYGLNACPPLLVGVGVATSVETAALLSKKALMRPIGSHNENERAASLEKMLEDGINKIGLGP
QGMSGNTSVMGVNIENTARHPSTIGVAVNVGCWSHRKGHIVFDKDLNYTITSHSGVNF

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=294, Percent_Identity=54.0816326530612, Blast_Score=348, Evalue=2e-97,
Organism=Escherichia coli, GI1790564, Length=258, Percent_Identity=24.031007751938, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.32 [H]

Molecular weight: Translated: 32243; Mature: 32112

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSEQISHMTDVMAKFVGYTGKVLPDDVTAKLEDLHKKETSKLADVIFTTMIENQRLAK
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELDRPSCQDTGVIQFLVECGTNFPLIGELEALLREAVIKATVDSPLRHNSVETFDEYNTG
HHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHCCC
KNVGKGTPTVFWEIVPNSDQCSIYTYMAGGGCSLPGKAMVLMPGAGYEGVTRFVLDVMTS
CCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
YGLNACPPLLVGVGVATSVETAALLSKKALMRPIGSHNENERAASLEKMLEDGINKIGLG
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHCCCC
PQGMSGNTSVMGVNIENTARHPSTIGVAVNVGCWSHRKGHIVFDKDLNYTITSHSGVNF
CCCCCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCCC
>Mature Secondary Structure 
SKSEQISHMTDVMAKFVGYTGKVLPDDVTAKLEDLHKKETSKLADVIFTTMIENQRLAK
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELDRPSCQDTGVIQFLVECGTNFPLIGELEALLREAVIKATVDSPLRHNSVETFDEYNTG
HHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHCCC
KNVGKGTPTVFWEIVPNSDQCSIYTYMAGGGCSLPGKAMVLMPGAGYEGVTRFVLDVMTS
CCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
YGLNACPPLLVGVGVATSVETAALLSKKALMRPIGSHNENERAASLEKMLEDGINKIGLG
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHCCCC
PQGMSGNTSVMGVNIENTARHPSTIGVAVNVGCWSHRKGHIVFDKDLNYTITSHSGVNF
CCCCCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]