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The map label for this gene is grxC [H]

Identifier: 194735256

GI number: 194735256

Start: 3772103

End: 3772354

Strand: Reverse

Name: grxC [H]

Synonym: SeSA_A3901

Alternate gene names: 194735256

Gene position: 3772354-3772103 (Counterclockwise)

Preceding gene: 194734466

Following gene: 194735826

Centisome position: 80.11

GC content: 50.4

Gene sequence:

>252_bases
ATGGCCAATATTGAAATCTACACCAAAGCAACCTGTCCGTTTTGCCATCGTGCAAAGACGCTGTTAAACAGCAAGGGCGT
GAGTTTCCAGGAAATTGCGATTGACGGCGACGCCGTGAAGCGTGAAGAGATGATCAAACGTAGTGGCCGAACGACGGTTC
CGCAAATTTTTATTGATGCACAGCACATTGGCGGTTGTGACGACTTGTATGCGCTGGATGCGCGTGGTGGACTGGATCCG
CTGTTGCGTTAA

Upstream 100 bases:

>100_bases
GTGCGCGGTAAGTGATTACCCGTCGTTTTCATGACGTAAGGGGAATGACTTGCCCTTGCGTCGACATGAAATCCATCGGG
TAAAAAACAGGAGCGAAGTC

Downstream 100 bases:

>100_bases
GGCGTACTCAAGTATTTAAGGACAACACTAAAGGGTTTTACACATGTCAGAACAAAATAACACTGAAATGGCTTTCCAGA
TCCAACGTATCTATACCAAG

Product: glutaredoxin 3

Products: NA

Alternate protein names: Grx3 [H]

Number of amino acids: Translated: 83; Mature: 82

Protein sequence:

>83_residues
MANIEIYTKATCPFCHRAKTLLNSKGVSFQEIAIDGDAVKREEMIKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDP
LLR

Sequences:

>Translated_83_residues
MANIEIYTKATCPFCHRAKTLLNSKGVSFQEIAIDGDAVKREEMIKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDP
LLR
>Mature_82_residues
ANIEIYTKATCPFCHRAKTLLNSKGVSFQEIAIDGDAVKREEMIKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPL
LR

Specific function: The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione re

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=87.9518072289157, Blast_Score=159, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9166; Mature: 9034

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIEIYTKATCPFCHRAKTLLNSKGVSFQEIAIDGDAVKREEMIKRSGRTTVPQIFIDA
CCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEC
QHIGGCDDLYALDARGGLDPLLR
CCCCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
ANIEIYTKATCPFCHRAKTLLNSKGVSFQEIAIDGDAVKREEMIKRSGRTTVPQIFIDA
CCEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEC
QHIGGCDDLYALDARGGLDPLLR
CCCCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]