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The map label for this gene is tolC [H]

Identifier: 194735152

GI number: 194735152

Start: 3254809

End: 3256278

Strand: Direct

Name: tolC [H]

Synonym: SeSA_A3372

Alternate gene names: 194735152

Gene position: 3254809-3256278 (Clockwise)

Preceding gene: 194735864

Following gene: 194735623

Centisome position: 69.12

GC content: 52.24

Gene sequence:

>1470_bases
ATGAAGAAATTGCTCCCCATCCTTATCGGCCTGAGCCTGTCGGGGTTCAGCACACTAAGCCAGGCAGAGAACCTGATGCA
AGTTTATCAGCAAGCACGCCTGAGCAACCCGGAATTGCGTAAATCCGCTGCCGATCGCGATGCTGCATTCGAAAAAATTA
ACGAAGCGCGTAGTCCTTTACTGCCGCAACTGGGTTTAGGTGCCGACTACACCTACAGCAACGGTTATCGCGATGCGAAC
GGTATCAACTCCAATGAAACCAGCGCTTCCCTGCAATTAACGCAGACGTTATTTGATATGTCGAAATGGCGTGGGCTCAC
CCTGCAAGAAAAAGCAGCAGGCATTCAGGATGTCACCTATCAGACCGATCAGCAGACGCTGATCCTCAATACCGCGAACG
CGTATTTTAAGGTATTGAACGCTATTGATGTGCTTTCCTATACCCAGGCACAAAAAGAGGCTATCTACCGTCAGTTAGAT
CAAACGACGCAACGTTTTAACGTGGGTCTGGTCGCCATTACCGACGTGCAAAACGCCCGTGCGCAATATGATACCGTACT
GGCGAATGAAGTGACCGCCCGCAACAACCTGGATAACGCGGTAGAAGAGCTGCGCCAGGTAACCGGCAATTATTACCCGG
AGCTGGCGTCGCTTAACGTCGAGCATTTTAAAACCGACAAACCCAAAGCTGTTAATGCGCTGCTGAAGGAAGCGGAAAAC
CGTAACCTGTCGCTGTTGCAGGCGCGTTTAAGTCAGGATCTGGCGCGCGAGCAAATCCGTCAGGCGCAGGATGGTCATCT
GCCGACGCTGAATTTAACGGCCTCAACCGGCATTTCTGATACCTCTTATAGCGGTTCTAAAACCAACTCCGCCCAGTACG
ACGATAGCAACATGGGGCAGAATAAAATCGGCCTGAACTTCTCCCTGCCGCTGTATCAAGGCGGGATGGTTAACTCGCAG
GTAAAACAGGCGCAGTATAACTTCGTCGGCGCAAGCGAACAGCTGGAAAGCGCGCACCGTAGCGTGGTGCAGACCGTACG
TTCTTCCTTTAACAATATTAACGCCTCCATCAGCAGCATCAACGCGTATAAACAGGCAGTCGTTTCCGCGCAAAGTTCTT
TGGATGCAATGGAAGCCGGTTACTCGGTCGGTACACGTACCATTGTTGACGTACTGGATGCCACCACCACTCTGTATGAT
GCCAAGCAGCAACTGGCCAACGCGCGTTATACCTATTTGATTAATCAGTTAAATATCAAATATGCGCTCGGTACGCTGAA
CGAGCAGGATCTGCTCGCGCTTAACAGTACGTTGGGTAAACCTATCCCGACGTCGCCGGAAAGCGTAGCGCCGGAAACGC
CAGATCAGGATGCTGCCGCAGACGGTTATAATGCCCATAGCGCCGCGCCGGCAGTACAGCCGACCGCCGCTCGCGCCAAC
AGCAATAACGGCAATCCATTCCGGCATTGA

Upstream 100 bases:

>100_bases
ACGTAACGCCAACTTTTTGCAGTGGCGGATTCTGCTAGAATCAGCAATTATTTTTACAAATTGATCAGCGCTAAATACTG
CTTCACAACAAGGAATGCAA

Downstream 100 bases:

>100_bases
TAAGTTATTCGCTGGCGCTGCGCTTATCAGACCTGTGCCCTTGTAGGTCTGGTAAGCGCGGCGCTACCTGTCATAAAGCC
GCGCCTGAACGTAAGACAAC

Product: outer membrane channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MKKLLPILIGLSLSGFSTLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDAN
GINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTYQTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLD
QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAEN
RNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSAQYDDSNMGQNKIGLNFSLPLYQGGMVNSQ
VKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYD
AKQQLANARYTYLINQLNIKYALGTLNEQDLLALNSTLGKPIPTSPESVAPETPDQDAAADGYNAHSAAPAVQPTAARAN
SNNGNPFRH

Sequences:

>Translated_489_residues
MKKLLPILIGLSLSGFSTLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDAN
GINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTYQTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLD
QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAEN
RNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSAQYDDSNMGQNKIGLNFSLPLYQGGMVNSQ
VKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYD
AKQQLANARYTYLINQLNIKYALGTLNEQDLLALNSTLGKPIPTSPESVAPETPDQDAAADGYNAHSAAPAVQPTAARAN
SNNGNPFRH
>Mature_489_residues
MKKLLPILIGLSLSGFSTLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDAN
GINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTYQTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLD
QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAEN
RNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSAQYDDSNMGQNKIGLNFSLPLYQGGMVNSQ
VKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYD
AKQQLANARYTYLINQLNIKYALGTLNEQDLLALNSTLGKPIPTSPESVAPETPDQDAAADGYNAHSAAPAVQPTAARAN
SNNGNPFRH

Specific function: Required for proper expression of outer membrane protein genes such as ompF, nmpC, protein 2, hemolysin, colicin V, or colicin E1. May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=493, Percent_Identity=89.6551724137931, Blast_Score=862, Evalue=0.0,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53397; Mature: 53397

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLPILIGLSLSGFSTLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPL
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
LPQLGLGADYTYSNGYRDANGINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTY
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHCEE
QTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNAR
ECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHH
AQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAEN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHCC
RNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSAQYDDSNMGQ
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
NKIGLNFSLPLYQGGMVNSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSI
CCCCCEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
NAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYDAKQQLANARYTYLINQLNIK
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHEEE
YALGTLNEQDLLALNSTLGKPIPTSPESVAPETPDQDAAADGYNAHSAAPAVQPTAARAN
EEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
SNNGNPFRH
CCCCCCCCC
>Mature Secondary Structure
MKKLLPILIGLSLSGFSTLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPL
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
LPQLGLGADYTYSNGYRDANGINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTY
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHCEE
QTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNAR
ECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHH
AQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAEN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHCC
RNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSAQYDDSNMGQ
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
NKIGLNFSLPLYQGGMVNSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSI
CCCCCEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
NAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYDAKQQLANARYTYLINQLNIK
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHEEE
YALGTLNEQDLLALNSTLGKPIPTSPESVAPETPDQDAAADGYNAHSAAPAVQPTAARAN
EEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
SNNGNPFRH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8801424 [H]