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The map label for this gene is foxA [H]

Identifier: 194735072

GI number: 194735072

Start: 425464

End: 427554

Strand: Direct

Name: foxA [H]

Synonym: SeSA_A0416

Alternate gene names: 194735072

Gene position: 425464-427554 (Clockwise)

Preceding gene: 194735807

Following gene: 194734893

Centisome position: 9.03

GC content: 53.04

Gene sequence:

>2091_bases
ATGTTTGCGACAACGCGTATGGCGCTATTGATAGGCGGAGCTATCGGCGGCGCGACTTTTCCTCTTTTTGCCCAGGAAAC
CACAAAAAATGATACCGTCATTGTCACCTCGCCCGTTCAGAGTGGCGCGACCAAGCTGGCGACGCCAGATATTGAAACGC
CGCAGTCGGTATCCATTATTACCCGCCAGCAGTTTGAAGAGCAGGGCGCAACCAGCGTGCGTCAGGCGGTCAGCTACACC
CCAGGCGTATACAGTAATCAGATAGGCGCGTCTAACCGCTTTGATTACATCGTATTGCGTGGTTTTTCGGACGGTAGTCT
GGATAACGTCTATCTCGACGGGTTAAAAATGATGGGCGACACCAATTCGCACAGTTCGTTGGTGGTTGACCCCTGGTTTC
TGGAAGATATCGAGGTGGTACGCGGCCCGGCGTCCGTTCTGTATGGACGTTCATCGCCAGGCGGCATTGTCGCGCTGACG
TCGCGAAAACCGGCGTTTGATGCCGGGGGAGAGGTGAAGCTGTTTGCCGGCAATCACAACCAGCGCGGGGCGGCTTTTGA
TGTGACCGGCCCACTGGATGACAATGAACGTGTGGCGGCGCGTCTTAGCGGCATGACACGTTACGCCGATTCGCAGTTTA
CCCCCTTGAAAGAGGAACGTTATGCGCTGATGCCGAGCCTGACCTGGCGAATTACCGATCGGACGCGTCTTGATCTTATG
GCCTATCTGCACCGTGATCCGGAAGGCGGTAGCCACTCCGGACTGCCTTATCAAGGCACGGTTGTACCTTATAACGGCGG
AAAAATTTCTAACACTTTCTTTGAAGGTGAAGATGACTACGACAAATACGATCGCCGTGAAAATATGGTGGGTTATAACA
TTGAGCATCTGTTCGATAACGGCTGGTCGGTACGGCAAAAATTGCGCTATTTGCATACCAAAGTGACGTTGAATCAGGTC
TATGCCGCAGGTTGGTTGAATGAAACGGCGCTGAATCGCGGCTATTCCGGCTCCGGGGAGAAAATGTCGGCTATCGCGCT
GGATAATCAGCTCGACGGCAGCGTGGATACCGGGGCGATTAATCATCGTCTGCTGGTGGGGATCGATTATCAGGATCGCA
GTAACCATACTACTGGCTATTATGGCGCGTTTCCGCCGATTGACGCTTTCAACCCTGTTTATGGCGCTCAGCCGGATTAC
ATTACGTTGTATAGCCGTGAAAAACATAAGCTGCGGCAGACCGGATACTATTTACAGGATCAGATGTCATGGGATCGCTG
GCGCTTTACGTTGGGCGGTCGTTACGATCGGGTCAGCGTGTCTAACATCGACAAACTTCATGATTCACGCAGCGATCTCG
ATAAAAACAACGTCAGCACCCGTGCTGCGTTGCTTTATCTGTTCGACAATGGCGTCGCCCCCTATCTCAGTTATTCTACC
GCGTTTACGCCGACCAGCTTCGCCGACGAAAACGGCAATGTGCTGGAACCGATGAAAGGCAAGCAGTGGGAGGCGGGGGT
AAAATACGAACCGCTGGGGGGGAACAGCCAGTTTAGCGCCGCCGTGTATCGTATTAACCAGACCAATATCGCGACCAAAG
AAGAACCTACCGATCCGTACCGCTCGATTGGTGAAATTGAGTCTAAAGGGGTGGAACTGGAGGCCATTAGCCATTTGTCG
GATAGCGTCCGTTTGCAGGCGGCGTATACCTATACTGATATCCGTTATAAGAAAAGTAGCCCGCAAGAGCAGGGTAAGCG
CGCGGTTTATGCTCCACGGAACCAGGCCAGCGCCTGGCTAAGCTACGATGTGAAAAGCGGTCTGTTAGAGGGGCTGACTT
TGGGCTCCGGCATCCGGTACGTCAACGGCGTGACCAGCGATCGCCTGAATACCCACACATTGCCGTCCTATACACTGGTC
GATATGGTGGTAGGGTATGATTTATCCAGCATTGGGTTAAATGGCTTGAGCGCCCAGCTCAACGTAAATAACCTGACGGA
CAAACGCTATGTCGCTGCCTGTAATTCGCTCTCTTATTGTTATTTTGGCGCCGAGCGTAGCATTGTAGGCAGCGTGTCAT
GGGCGTTTTGA

Upstream 100 bases:

>100_bases
TTATCATTGCGCATAGGCAATCTGGCGTTACGCATAGTGGTCCGTCATCTCTAAAAGGTAATAATTCTTATTTACAATAA
AGATGCCTTTGGAGATGTTC

Downstream 100 bases:

>100_bases
TAACGCTTATCGTCCGGTAGCAAAGGCTACCGGACAAACATTAGCGGTGCGTCACGCCTTCATAGAGAAGTCTGAGCGCA
AACATCCCGATAATGGCGCC

Product: ferrichrome-iron receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATKLATPDIETPQSVSIITRQQFEEQGATSVRQAVSYT
PGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVALT
SRKPAFDAGGEVKLFAGNHNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDRTRLDLM
AYLHRDPEGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDNGWSVRQKLRYLHTKVTLNQV
YAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAINHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDY
ITLYSREKHKLRQTGYYLQDQMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYST
AFTPTSFADENGNVLEPMKGKQWEAGVKYEPLGGNSQFSAAVYRINQTNIATKEEPTDPYRSIGEIESKGVELEAISHLS
DSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWLSYDVKSGLLEGLTLGSGIRYVNGVTSDRLNTHTLPSYTLV
DMVVGYDLSSIGLNGLSAQLNVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF

Sequences:

>Translated_696_residues
MFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATKLATPDIETPQSVSIITRQQFEEQGATSVRQAVSYT
PGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVALT
SRKPAFDAGGEVKLFAGNHNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDRTRLDLM
AYLHRDPEGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDNGWSVRQKLRYLHTKVTLNQV
YAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAINHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDY
ITLYSREKHKLRQTGYYLQDQMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYST
AFTPTSFADENGNVLEPMKGKQWEAGVKYEPLGGNSQFSAAVYRINQTNIATKEEPTDPYRSIGEIESKGVELEAISHLS
DSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWLSYDVKSGLLEGLTLGSGIRYVNGVTSDRLNTHTLPSYTLV
DMVVGYDLSSIGLNGLSAQLNVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF
>Mature_696_residues
MFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATKLATPDIETPQSVSIITRQQFEEQGATSVRQAVSYT
PGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVALT
SRKPAFDAGGEVKLFAGNHNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDRTRLDLM
AYLHRDPEGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDNGWSVRQKLRYLHTKVTLNQV
YAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAINHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDY
ITLYSREKHKLRQTGYYLQDQMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYST
AFTPTSFADENGNVLEPMKGKQWEAGVKYEPLGGNSQFSAAVYRINQTNIATKEEPTDPYRSIGEIESKGVELEAISHLS
DSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWLSYDVKSGLLEGLTLGSGIRYVNGVTSDRLNTHTLPSYTLV
DMVVGYDLSSIGLNGLSAQLNVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=738, Percent_Identity=36.449864498645, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1787024, Length=745, Percent_Identity=24.6979865771812, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI1787344, Length=723, Percent_Identity=24.896265560166, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1790743, Length=656, Percent_Identity=21.6463414634146, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 76992; Mature: 76992

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATKLATPDIETPQSVSII
CCCCCEEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEHH
TRQQFEEQGATSVRQAVSYTPGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCEEEECC
TNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVALTSRKPAFDAGGEVKLFAGNHN
CCCCCEEEECCHHHHHHHHHCCCHHHEECCCCCCCEEEECCCCCCCCCCCCEEEEECCCC
QRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDRTRLDLM
CCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCEEEEECCCHHHHHH
AYLHRDPEGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDN
HHHHCCCCCCCCCCCCCCCEEEEECCCEEECCEECCCCCHHHHHHHCCCCCCCHHHHHCC
GWSVRQKLRYLHTKVTLNQVYAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAI
CHHHHHHHHHHHHHEEHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCC
NHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDYITLYSREKHKLRQTGYYLQD
CCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHCCCEEHH
QMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYST
CCCCCCEEEEECCCCCEEEHHHHHHHHCCHHHCCCCCCCCEEEEEEEECCCCCCCEECCC
AFTPTSFADENGNVLEPMKGKQWEAGVKYEPLGGNSQFSAAVYRINQTNIATKEEPTDPY
CCCCCCCCCCCCCEECCCCCCCCCCCCEECCCCCCCCEEEEEEEEECCCCCCCCCCCCHH
RSIGEIESKGVELEAISHLSDSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWL
HHHHHHHHCCEEEEHHHHCCCCEEEEEEEEEEEEEECCCCCHHHCCEEEECCCCCCCEEE
SYDVKSGLLEGLTLGSGIRYVNGVTSDRLNTHTLPSYTLVDMVVGYDLSSIGLNGLSAQL
EECHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCCEEEEE
NVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF
ECCCCCCCHHHHHHCCCEEEEECCCCCEEEEEEECC
>Mature Secondary Structure
MFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATKLATPDIETPQSVSII
CCCCCEEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEHH
TRQQFEEQGATSVRQAVSYTPGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCEEEECC
TNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVALTSRKPAFDAGGEVKLFAGNHN
CCCCCEEEECCHHHHHHHHHCCCHHHEECCCCCCCEEEECCCCCCCCCCCCEEEEECCCC
QRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDRTRLDLM
CCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCEEEEECCCHHHHHH
AYLHRDPEGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDN
HHHHCCCCCCCCCCCCCCCEEEEECCCEEECCEECCCCCHHHHHHHCCCCCCCHHHHHCC
GWSVRQKLRYLHTKVTLNQVYAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAI
CHHHHHHHHHHHHHEEHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCC
NHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDYITLYSREKHKLRQTGYYLQD
CCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHCCCEEHH
QMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYST
CCCCCCEEEEECCCCCEEEHHHHHHHHCCHHHCCCCCCCCEEEEEEEECCCCCCCEECCC
AFTPTSFADENGNVLEPMKGKQWEAGVKYEPLGGNSQFSAAVYRINQTNIATKEEPTDPY
CCCCCCCCCCCCCEECCCCCCCCCCCCEECCCCCCCCEEEEEEEEECCCCCCCCCCCCHH
RSIGEIESKGVELEAISHLSDSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWL
HHHHHHHHCCEEEEHHHHCCCCEEEEEEEEEEEEEECCCCCHHHCCEEEECCCCCCCEEE
SYDVKSGLLEGLTLGSGIRYVNGVTSDRLNTHTLPSYTLVDMVVGYDLSSIGLNGLSAQL
EECHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCCEEEEE
NVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF
ECCCCCCCHHHHHHCCCEEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]