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The map label for this gene is ygfA [H]

Identifier: 194735044

GI number: 194735044

Start: 3124837

End: 3125433

Strand: Direct

Name: ygfA [H]

Synonym: SeSA_A3233

Alternate gene names: 194735044

Gene position: 3124837-3125433 (Clockwise)

Preceding gene: 194738037

Following gene: 194735077

Centisome position: 66.36

GC content: 57.62

Gene sequence:

>597_bases
ATGACGCAACTTCCCGAACTCTCTTTATCACGACAAGAAATCCGCCGAATGATTCGGCAACGTCGCCGTGCGCTAACGCC
AGAGCAGCAACGCCGCTTTGGTCAACAGGCCGCCGCCCGAATGCTCAGCTTTCCTCCCGTCGTGATGGCGCACACTGTCG
CCGTGTTTCTCTCCTTTGATGGCGAACTCGACACCCAGCCGCTGATAGAACAGCTATGGCAAGCGGGCAAGCGCGTCTAC
CTTCCGGTTCTTCATCCCTTCAGCCCCGGCAACCTCCTGTTCCTGCACTATCATCCGCAGAGTGCACTGGTGACCAACCG
CTTAAAGATCCGGGAGCCACGGCTTGATGTCCGCGACGTATTGCCGCTGGCAAAGCTGGATGTGCTGGTAACGCCGTTAG
TGGCGTTTGACGAAGGCGGGCAGCGCCTGGGGATGGGCGGCGGATTTTATGACCGTACGTTGCAAAACTGGCAGCAGCAT
AAGATCCTACCTGTGGGCTACGCGCATGATTGCCAGTTAGTGGAAAAGCTGCCGGTTGAAGAGTGGGATATCCCGCTGCC
TGCGGTGGTAACGCCATCCAAAATTTGGGAGTGGTAG

Upstream 100 bases:

>100_bases
AGCCTTAAAACTGTGACGACACATTCACCTTGAACCAAGGGTTCAAGGGTTACAGCCTGCGGCGGCATCTCGGAGATTCC
CCTTCTGACTGGCAACAGCC

Downstream 100 bases:

>100_bases
CCGTGTTTTGCCGATTGACAGCGTCGCTTTTTTAACCTAAATTTCTCGGTGAAGGGTGAGGGAGGCGAACCTCCCTCCTG
CGTACTCACTGTTAATATGC

Product: putative ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTQLPELSLSRQEIRRMIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWQAGKRVY
LPVLHPFSPGNLLFLHYHPQSALVTNRLKIREPRLDVRDVLPLAKLDVLVTPLVAFDEGGQRLGMGGGFYDRTLQNWQQH
KILPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKIWEW

Sequences:

>Translated_198_residues
MTQLPELSLSRQEIRRMIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWQAGKRVY
LPVLHPFSPGNLLFLHYHPQSALVTNRLKIREPRLDVRDVLPLAKLDVLVTPLVAFDEGGQRLGMGGGFYDRTLQNWQQH
KILPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKIWEW
>Mature_197_residues
TQLPELSLSRQEIRRMIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWQAGKRVYL
PVLHPFSPGNLLFLHYHPQSALVTNRLKIREPRLDVRDVLPLAKLDVLVTPLVAFDEGGQRLGMGGGFYDRTLQNWQQHK
ILPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKIWEW

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=192, Percent_Identity=27.0833333333333, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1789278, Length=182, Percent_Identity=87.3626373626374, Blast_Score=335, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 22830; Mature: 22699

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLPELSLSRQEIRRMIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFD
CCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECC
GELDTQPLIEQLWQAGKRVYLPVLHPFSPGNLLFLHYHPQSALVTNRLKIREPRLDVRDV
CCCCHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCHHHHHCCCEECCCCCCHHHH
LPLAKLDVLVTPLVAFDEGGQRLGMGGGFYDRTLQNWQQHKILPVGYAHDCQLVEKLPVE
HHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCC
EWDIPLPAVVTPSKIWEW
CCCCCCCCEECHHHHCCC
>Mature Secondary Structure 
TQLPELSLSRQEIRRMIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFD
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECC
GELDTQPLIEQLWQAGKRVYLPVLHPFSPGNLLFLHYHPQSALVTNRLKIREPRLDVRDV
CCCCHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCHHHHHCCCEECCCCCCHHHH
LPLAKLDVLVTPLVAFDEGGQRLGMGGGFYDRTLQNWQQHKILPVGYAHDCQLVEKLPVE
HHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCC
EWDIPLPAVVTPSKIWEW
CCCCCCCCEECHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]