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The map label for this gene is kdpE [H]

Identifier: 194734914

GI number: 194734914

Start: 832106

End: 832783

Strand: Reverse

Name: kdpE [H]

Synonym: SeSA_A0860

Alternate gene names: 194734914

Gene position: 832783-832106 (Counterclockwise)

Preceding gene: 194735142

Following gene: 194736885

Centisome position: 17.68

GC content: 56.34

Gene sequence:

>678_bases
GTGACAAACGTTCTGATTGTTGAAGATGAACAGGCCATCCGCCGCTTTCTGCGCGCTGCGCTGGAAGGCGACGGCCTGCG
CGTGTATGAAGCTGAAACATTACAACGTGGTTTACTGGAAGCCGCCACGCGAAAGCCCGATCTGATTATTCTCGATCTCG
GCCTGCCGGACGGCGATGGAATCGATTTTATTCGCGACCTGCGTCAGTGGAGCGCAATACCGGTGATTGTCCTTTCCGCC
CGCAGCGAAGAAAGCGATAAGATTGCCGCGCTTGACGCCGGAGCTGATGATTACCTGAGCAAGCCATTCGGCATTGGCGA
GTTGCAGGCGCGTTTGCGTGTCGCGCTGCGACGGCACGCCGCCAGCCCTTGCGCCGATCCGATCGTCCGCTTTTCCGGCG
TGACGGTCGATCTCGCCGCACGGTTGATCCACCGTGGCGACGAAGAAATCCATCTGACGCCGATTGAGTTCCGCCTGCTG
GCGGTATTACTCAATAATGCCGGCAAGGTATTAACCCAACGGCAGTTATTAAACCAGGTCTGGGGCCCTAACGCCGTGGA
GCATAGCCACTATTTGCGCATCTATATGGGACATTTACGCCAGAAACTGGAACAAGATCCCACCCGCCCACGCCATTTTA
TTACCGAAACCGGAATTGGCTATCGCTTTATGCCGTGA

Upstream 100 bases:

>100_bases
GCACGCTTACCGCCTATAATCGACCGCAGGGCGGCGCCTGTTTCCGTGTGACGCTGCCGCAAGGAAAGCCACCTGAACTT
GATGATTTTCATGAGGATAT

Downstream 100 bases:

>100_bases
ATAGCCATTCATTATTTTTAAATAACTTCTAATTTTTATGTCATTTATTTTCGGCGTCGCGAATAATTATTTTCGCGGCG
ATATTATATTTTATGAAGGA

Product: DNA-binding transcriptional activator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTNVLIVEDEQAIRRFLRAALEGDGLRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIDFIRDLRQWSAIPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHAASPCADPIVRFSGVTVDLAARLIHRGDEEIHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPTRPRHFITETGIGYRFMP

Sequences:

>Translated_225_residues
MTNVLIVEDEQAIRRFLRAALEGDGLRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIDFIRDLRQWSAIPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHAASPCADPIVRFSGVTVDLAARLIHRGDEEIHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPTRPRHFITETGIGYRFMP
>Mature_224_residues
TNVLIVEDEQAIRRFLRAALEGDGLRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIDFIRDLRQWSAIPVIVLSAR
SEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHAASPCADPIVRFSGVTVDLAARLIHRGDEEIHLTPIEFRLLA
VLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPTRPRHFITETGIGYRFMP

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=92.4107142857143, Blast_Score=426, Evalue=1e-121,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=37.5, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=36.4864864864865, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=34.051724137931, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=36.7713004484305, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=35.1351351351351, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=36.3636363636364, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=32.8828828828829, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=33.4821428571429, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=31.140350877193, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=34.0909090909091, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=31.2775330396476, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=29.9559471365639, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=26.890756302521, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=33.0508474576271, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=136, Percent_Identity=32.3529411764706, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790437, Length=131, Percent_Identity=31.2977099236641, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25300; Mature: 25169

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVLIVEDEQAIRRFLRAALEGDGLRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDG
CCCEEEECCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
IDFIRDLRQWSAIPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHA
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHC
ASPCADPIVRFSGVTVDLAARLIHRGDEEIHLTPIEFRLLAVLLNNAGKVLTQRQLLNQV
CCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
WGPNAVEHSHYLRIYMGHLRQKLEQDPTRPRHFITETGIGYRFMP
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEECC
>Mature Secondary Structure 
TNVLIVEDEQAIRRFLRAALEGDGLRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDG
CCEEEECCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
IDFIRDLRQWSAIPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHA
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHC
ASPCADPIVRFSGVTVDLAARLIHRGDEEIHLTPIEFRLLAVLLNNAGKVLTQRQLLNQV
CCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
WGPNAVEHSHYLRIYMGHLRQKLEQDPTRPRHFITETGIGYRFMP
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]