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The map label for this gene is perM [H]

Identifier: 194734852

GI number: 194734852

Start: 2609781

End: 2610869

Strand: Reverse

Name: perM [H]

Synonym: SeSA_A2730

Alternate gene names: 194734852

Gene position: 2610869-2609781 (Counterclockwise)

Preceding gene: 194735099

Following gene: 194734220

Centisome position: 55.44

GC content: 54.64

Gene sequence:

>1089_bases
TTGAGTTCTGGGAAGGGTTTTATGCTCGAAATGTTAATGCAATGGTATCGCCGTCGCTTCAGCGACCCGGAGGCGATTGC
CTTGCTGGTCATTCTGGTGGCTGGTTTTAGCATCCTCTTTTTCTTTAGCGGCCTGTTAGCGCCGCTGCTGGTCGCAATCG
TACTGGCCTACCTGCTGGAGTGGCCGACGGCGCGCCTGCAGGCGATTGGCTGTTCCCGGCGCTGGGCAGCCTCCATTGTC
CTTATCCTCTTTGTCGGCATTCTGTTATTAATGGCGTTTGTGGTGATGCCGATTGCCTGGCAGCAGGGTATTTACCTGAT
TCGTGATATGCCCGGTATGCTGAATAAACTGTCCGATTTTGCCGCGACCTTGCCGCGACGCTATCCGGCGCTGATGGATG
CGGGCATTATTGATGCGATGGCGGAAAACATGCGTACCCGGATGCTTAACATGGGCGATTCGGTGGTGAAGTATTCGCTG
GCTTCGTTAGTCGGGCTACTGACGCTGGCGGTATATCTGGTGCTGGTGCCGCTGATGGTCTTTTTCCTGGTAAAAGATAA
AGAGCAGATGCTGAATGCCGTGCGCCGCGTGCTGCCGCGTAATCGCGGGCTGGCGGGGCAGGTGTGGAATGAGATGAATC
AGCAGATCACCAACTATATCCGCGGAAAAGTGCTGGAGATGGTGGTGGTGGGCGTAGCGACCTGGCTGGGCTTTTTGCTG
TTTGGCCTCAATTATTCGCTACTGCTGGCGGTACTGGTGGGCTTTTCGGTCCTGATCCCCTATATCGGCGCCTTTGTGGT
GACAATTCCGGTGGTGGGCGTCGCGCTGTTTCAGTTTGGCCTGGGGACGGAATTCTGGAGCTGTTTTGCCGTTTATCTGA
TTATTCAGGCGCTGGATGGCAATTTGCTGGTACCGGTACTTTTCTCCGAAGCGGTGAATTTGCATCCGCTGGTGATTATT
CTGTCAGTGGTGATTTTCGGCGGTCTGTGGGGTTTTTGGGGAGTGTTTTTCGCCATTCCATTGGCGACGCTGATTAAAGC
CGTTGTCCATGCCTGGCCGGATGGTCAGGTGACAGATGCCTCATCCTGA

Upstream 100 bases:

>100_bases
TGATGAGCACAGACTCACTATTTTAGTTTCCTGAATCAACGATAAAAAGCGAAGTCTTTTTTGTGACATTTCGATACAAT
TCGGCATCACAATCCCGCAG

Downstream 100 bases:

>100_bases
GCGGCCTGTACAAAAGTTGTAAAGCGTGAACGACATCATAGTGCCCTGCCGCCATTTTGCGCACGCCTGATGAGGGACAA
GCGCTTAGAAAGCCGCTCTT

Product: permease PerM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSSGKGFMLEMLMQWYRRRFSDPEAIALLVILVAGFSILFFFSGLLAPLLVAIVLAYLLEWPTARLQAIGCSRRWAASIV
LILFVGILLLMAFVVMPIAWQQGIYLIRDMPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRTRMLNMGDSVVKYSL
ASLVGLLTLAVYLVLVPLMVFFLVKDKEQMLNAVRRVLPRNRGLAGQVWNEMNQQITNYIRGKVLEMVVVGVATWLGFLL
FGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGLGTEFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVII
LSVVIFGGLWGFWGVFFAIPLATLIKAVVHAWPDGQVTDASS

Sequences:

>Translated_362_residues
MSSGKGFMLEMLMQWYRRRFSDPEAIALLVILVAGFSILFFFSGLLAPLLVAIVLAYLLEWPTARLQAIGCSRRWAASIV
LILFVGILLLMAFVVMPIAWQQGIYLIRDMPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRTRMLNMGDSVVKYSL
ASLVGLLTLAVYLVLVPLMVFFLVKDKEQMLNAVRRVLPRNRGLAGQVWNEMNQQITNYIRGKVLEMVVVGVATWLGFLL
FGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGLGTEFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVII
LSVVIFGGLWGFWGVFFAIPLATLIKAVVHAWPDGQVTDASS
>Mature_361_residues
SSGKGFMLEMLMQWYRRRFSDPEAIALLVILVAGFSILFFFSGLLAPLLVAIVLAYLLEWPTARLQAIGCSRRWAASIVL
ILFVGILLLMAFVVMPIAWQQGIYLIRDMPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRTRMLNMGDSVVKYSLA
SLVGLLTLAVYLVLVPLMVFFLVKDKEQMLNAVRRVLPRNRGLAGQVWNEMNQQITNYIRGKVLEMVVVGVATWLGFLLF
GLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGLGTEFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIIL
SVVIFGGLWGFWGVFFAIPLATLIKAVVHAWPDGQVTDASS

Specific function: Unknown

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1788838, Length=352, Percent_Identity=94.0340909090909, Blast_Score=662, Evalue=0.0,
Organism=Escherichia coli, GI87082271, Length=205, Percent_Identity=26.8292682926829, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 40060; Mature: 39929

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGKGFMLEMLMQWYRRRFSDPEAIALLVILVAGFSILFFFSGLLAPLLVAIVLAYLLE
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WPTARLQAIGCSRRWAASIVLILFVGILLLMAFVVMPIAWQQGIYLIRDMPGMLNKLSDF
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHH
AATLPRRYPALMDAGIIDAMAENMRTRMLNMGDSVVKYSLASLVGLLTLAVYLVLVPLMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFLVKDKEQMLNAVRRVLPRNRGLAGQVWNEMNQQITNYIRGKVLEMVVVGVATWLGFLL
HHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGLGTEFWSCFAVYLIIQALDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
NLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPLATLIKAVVHAWPDGQVTDA
CEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SS
CC
>Mature Secondary Structure 
SSGKGFMLEMLMQWYRRRFSDPEAIALLVILVAGFSILFFFSGLLAPLLVAIVLAYLLE
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WPTARLQAIGCSRRWAASIVLILFVGILLLMAFVVMPIAWQQGIYLIRDMPGMLNKLSDF
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHH
AATLPRRYPALMDAGIIDAMAENMRTRMLNMGDSVVKYSLASLVGLLTLAVYLVLVPLMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFLVKDKEQMLNAVRRVLPRNRGLAGQVWNEMNQQITNYIRGKVLEMVVVGVATWLGFLL
HHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGLGTEFWSCFAVYLIIQALDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
NLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPLATLIKAVVHAWPDGQVTDA
CEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]