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The map label for this gene is cdaR [H]

Identifier: 194734848

GI number: 194734848

Start: 2608318

End: 2609499

Strand: Reverse

Name: cdaR [H]

Synonym: SeSA_A2728

Alternate gene names: 194734848

Gene position: 2609499-2608318 (Counterclockwise)

Preceding gene: 194734220

Following gene: 194735573

Centisome position: 55.41

GC content: 49.49

Gene sequence:

>1182_bases
GTGTTGAGAAAACATTACTTGAAAGGGTATACCGCGCGGCAAATTGTACAGCGAGCCATGAAAATTATTCCTTACTCGGT
AAACGTCATGGATGAACATGGCGTCATTATCGCGTCTGGCGAACCTTCGCGGCTTCGCCAGCGTCACGAAGGGGCCATTC
TGGCGCTGAAGGAAAACCGTATTGTAGAAATTGATTCCGCTACCGCCAATCAGCTAAAAGGCGTGCGATCCGGCATTAAT
CTTCCCATCTCTTTTCATGAACAGCTTATCGGCGTGGTCGGCATTACCGGCGAGCCGGAGGAGGTTCGCGCGTATGCCGA
GCTGGTTAAAATGGCGGCGGAGCTGGTGATCGAGCATATGGTGCTGATCGAACAGCGACAGTGGGATAAACGCTATCGCG
AAGAGCTGATCAACCAATTGATTTTGCGAGAAAATTCAACAGAGTCGTTGCGCTCTATGGCGGCCTATCTGGGCATTGAT
CTGGCGGTTCCCAGAGTGGTGCTGATTATTGAACTTTCCCAGCCGGATCGCGAAGCGCTGCGCAATGTAATGGATTATTT
CGAGAATCACGCGCGCAACCATTTGGTGACGTTTACCGAATTTAATGAATTAATCATTATTAAGCCTATCACGTTAAAAG
AGGGAAAGTGGAATACCCGCCAGGAAATGGGCGAATTGCAGATTTTTAAATCATGGGCTGCATCATCGGGCTTTAGCCGT
ATTTTGGTTGGGGGTTATTTTGCCGGCGAGACGGGATTGCACCGATCTTTGCTCACTGCGAGAGCCACGCAGGCGATGGC
GAAAAGACAAAAGCTGCGCAGCCAGTACATTTTTTATCATGACCATGCGCTTCCCGCGCTGCTAAGCGGGCTGTCTGAAA
GTTGGCAAGTGCAGGAGCTATCGCGTCTGTGGCTGCAACTGGCGCAACATGACGCGAAAGGCGTATTGCAACAGACGCTG
CGGACCTGGTTTGAACATAATTGTGACCTGACGCAAACAGCCAAAGCATTGCATATTCATGTGAATACATTGCGCTATCG
CTTACAGCGCTGTGAGGATATTACACACATAAAAATCAACGAGTTAAAAAGTACGCTTTGGCTTTATATCGGTATGGAGC
TCCAGGCCGAATCTGTACCGTCCGACAAGTTACCGCTGCCAGGTCGAATCGAAATTTGTTGA

Upstream 100 bases:

>100_bases
ACTTAACCTAAGCATTCTTCTGAGAAATTCGTTAATAAGTGACATCATTGATGCGAGATTGCTTTTTTAATGTAAAGCGA
TAACGAAACAGGGAATGAGT

Downstream 100 bases:

>100_bases
AAGCTCCAGCGGATTTTTAGGCGGGTTTTTCCATACTGCGCGCTCCATGTTAAAGGAGGCGCAGTATATGACGTCGATAT
CCACCCTGGGAGCCATTGCC

Product: transcriptional regulator, CdaR

Products: NA

Alternate protein names: Sugar diacid regulator [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MLRKHYLKGYTARQIVQRAMKIIPYSVNVMDEHGVIIASGEPSRLRQRHEGAILALKENRIVEIDSATANQLKGVRSGIN
LPISFHEQLIGVVGITGEPEEVRAYAELVKMAAELVIEHMVLIEQRQWDKRYREELINQLILRENSTESLRSMAAYLGID
LAVPRVVLIIELSQPDREALRNVMDYFENHARNHLVTFTEFNELIIIKPITLKEGKWNTRQEMGELQIFKSWAASSGFSR
ILVGGYFAGETGLHRSLLTARATQAMAKRQKLRSQYIFYHDHALPALLSGLSESWQVQELSRLWLQLAQHDAKGVLQQTL
RTWFEHNCDLTQTAKALHIHVNTLRYRLQRCEDITHIKINELKSTLWLYIGMELQAESVPSDKLPLPGRIEIC

Sequences:

>Translated_393_residues
MLRKHYLKGYTARQIVQRAMKIIPYSVNVMDEHGVIIASGEPSRLRQRHEGAILALKENRIVEIDSATANQLKGVRSGIN
LPISFHEQLIGVVGITGEPEEVRAYAELVKMAAELVIEHMVLIEQRQWDKRYREELINQLILRENSTESLRSMAAYLGID
LAVPRVVLIIELSQPDREALRNVMDYFENHARNHLVTFTEFNELIIIKPITLKEGKWNTRQEMGELQIFKSWAASSGFSR
ILVGGYFAGETGLHRSLLTARATQAMAKRQKLRSQYIFYHDHALPALLSGLSESWQVQELSRLWLQLAQHDAKGVLQQTL
RTWFEHNCDLTQTAKALHIHVNTLRYRLQRCEDITHIKINELKSTLWLYIGMELQAESVPSDKLPLPGRIEIC
>Mature_393_residues
MLRKHYLKGYTARQIVQRAMKIIPYSVNVMDEHGVIIASGEPSRLRQRHEGAILALKENRIVEIDSATANQLKGVRSGIN
LPISFHEQLIGVVGITGEPEEVRAYAELVKMAAELVIEHMVLIEQRQWDKRYREELINQLILRENSTESLRSMAAYLGID
LAVPRVVLIIELSQPDREALRNVMDYFENHARNHLVTFTEFNELIIIKPITLKEGKWNTRQEMGELQIFKSWAASSGFSR
ILVGGYFAGETGLHRSLLTARATQAMAKRQKLRSQYIFYHDHALPALLSGLSESWQVQELSRLWLQLAQHDAKGVLQQTL
RTWFEHNCDLTQTAKALHIHVNTLRYRLQRCEDITHIKINELKSTLWLYIGMELQAESVPSDKLPLPGRIEIC

Specific function: Seems to regulate the expression of the operons for the enzymes involved in D-galactarate, D-glucarate and D-glycerate utilization [H]

COG id: COG3835

COG function: function code KT; Sugar diacid utilization regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdaR family [H]

Homologues:

Organism=Escherichia coli, GI87081694, Length=380, Percent_Identity=38.1578947368421, Blast_Score=262, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008599 [H]

Pfam domain/function: PF05651 Diacid_rec [H]

EC number: NA

Molecular weight: Translated: 45158; Mature: 45158

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRKHYLKGYTARQIVQRAMKIIPYSVNVMDEHGVIIASGEPSRLRQRHEGAILALKENR
CCCCHHHCCCHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCHHHHHHCCCCEEEEECCC
IVEIDSATANQLKGVRSGINLPISFHEQLIGVVGITGEPEEVRAYAELVKMAAELVIEHM
EEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VLIEQRQWDKRYREELINQLILRENSTESLRSMAAYLGIDLAVPRVVLIIELSQPDREAL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHH
RNVMDYFENHARNHLVTFTEFNELIIIKPITLKEGKWNTRQEMGELQIFKSWAASSGFSR
HHHHHHHHHHCCCCEEEEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCE
ILVGGYFAGETGLHRSLLTARATQAMAKRQKLRSQYIFYHDHALPALLSGLSESWQVQEL
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHCCCCCHHHHHH
SRLWLQLAQHDAKGVLQQTLRTWFEHNCDLTQTAKALHIHVNTLRYRLQRCEDITHIKIN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEHHHHHHHHHHHHCCCCEEEHH
ELKSTLWLYIGMELQAESVPSDKLPLPGRIEIC
HHHHHEEEEEEEEEEECCCCCCCCCCCCCEECC
>Mature Secondary Structure
MLRKHYLKGYTARQIVQRAMKIIPYSVNVMDEHGVIIASGEPSRLRQRHEGAILALKENR
CCCCHHHCCCHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCHHHHHHCCCCEEEEECCC
IVEIDSATANQLKGVRSGINLPISFHEQLIGVVGITGEPEEVRAYAELVKMAAELVIEHM
EEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VLIEQRQWDKRYREELINQLILRENSTESLRSMAAYLGIDLAVPRVVLIIELSQPDREAL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHH
RNVMDYFENHARNHLVTFTEFNELIIIKPITLKEGKWNTRQEMGELQIFKSWAASSGFSR
HHHHHHHHHHCCCCEEEEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCE
ILVGGYFAGETGLHRSLLTARATQAMAKRQKLRSQYIFYHDHALPALLSGLSESWQVQEL
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHCCCCCHHHHHH
SRLWLQLAQHDAKGVLQQTLRTWFEHNCDLTQTAKALHIHVNTLRYRLQRCEDITHIKIN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEHHHHHHHHHHHHCCCCEEEHH
ELKSTLWLYIGMELQAESVPSDKLPLPGRIEIC
HHHHHEEEEEEEEEEECCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10762278 [H]