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The map label for this gene is mdtA [H]

Identifier: 194734679

GI number: 194734679

Start: 2235828

End: 2237069

Strand: Direct

Name: mdtA [H]

Synonym: SeSA_A2363

Alternate gene names: 194734679

Gene position: 2235828-2237069 (Clockwise)

Preceding gene: 194737588

Following gene: 194735045

Centisome position: 47.48

GC content: 58.29

Gene sequence:

>1242_bases
ATGAAAGGCAGTAATACTTTCCGCTGGGCAATAGCGATTGGGGTTGTAGTGGCCGCCGCCGCATTCTGGTTCTGGCATAG
CCGTAGCGAAAGCCCGACCGCCGCGCCGGGCGTCGCCGCGCAAGCGCCGCATACCGCCGCCGCAGGTCGCCGCGGTATGC
GCGACGCCCCTCTGGCGCCGGTACAGGCCGCGACCGCGACCACGCAAGCCGTACCGCGCTATCTGAGCGGGCTGGGTACC
GTGACCGCAGCGAATACCGTTACGGTGCGTAGCCGCGTGGATGGTCAACTCATCGCCCTGCACTTTCAGGAAGGTCAGCA
GGTCAACACAGGCGATCTGCTGGCGCAAATCGATCCCAGCCAGTTTAAGGTCGCCCTGGCGCAGGCGCAGGGACAGTTGG
CGAAAGATAACGCTACGCTGGCGAATGCGCGTCGTGATCTGGCGCGCTATCAGCAACTGGCAAAAACCAATCTGGTTTCC
CGTCAGGAACTGGATGCGCAACAGGCGCTGGTCAACGAAACCCAGGGAACCATTAAAGCGGATGAAGCCAATGTCGCCAG
CGCGCAGTTACAGCTCGACTGGAGTCGTATCACGGCCCCGGTCTCGGGACGCGTGGGTCTGAAACAGGTGGATGTCGGCA
ACCAGATTTCCAGCAGCGATACCGCCGGTATTGTCGTCATTACGCAAACGCACCCGATTGATCTCATTTTTACTCTGCCG
GAAAGCGATATCGCGACCGTAGTTCAGGCACAGAAAGCGGGGAAAGCGCTGGTCGTAGAAGCCTGGGATCGGACTAACTC
GCACAAACTGAGCGAAGGTGTGTTGCTCAGTCTGGACAACCAGATTGATCCCACGACGGGAACGATCAAAATTAAAGCGC
GCTTTACCAATCAGGACGATACGCTGTTCCCCAATCAATTTGTGAACGCCCGGATGCTGGTCGATACCGAACAAAATGCC
GTTGTGGTGCCTGCCGCGGCGGTGCAAATGGGCAATGAGGGCCACTTTGTGTGGGTGCTGAACGACGAAAATAACGTCAG
CAAGAAGCGGGTAAAAATCGGTATTCAGGATAACCAAAACGTGGTGATCAGCGCAGGCTTGTCGGCAGGCGATCGCGTCG
TTACCGATGGTATTGATCGGCTGACGGAAGGCGCAAAAGTCGAGGTCGTTGAGCCGCAAACCACCGTGGCGGATGAAAAA
TCCCCTTCCCGCCATGAAGGTCAAAAAGGAGCGCGCGCCTGA

Upstream 100 bases:

>100_bases
GACCGTGTTCCATAATTCCTCCATTTTTCTCCCTTCCCTGCTGACTACAATAGAGGGAGCAACATTCCGCAAAACGTTTC
TGGATGAGAAACTTATACCG

Downstream 100 bases:

>100_bases
TGCAGGTATTACCTCCGGGCAGCACGGGCGGCCCTTCGCGTCTGTTTATTCTGCGCCCCGTGGCCACCACTCTGCTGATG
GCGGCGATTTTACTCGCCGG

Product: multidrug efflux system subunit MdtA

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAPHTAAAGRRGMRDAPLAPVQAATATTQAVPRYLSGLGT
VTAANTVTVRSRVDGQLIALHFQEGQQVNTGDLLAQIDPSQFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVS
RQELDAQQALVNETQGTIKADEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
ESDIATVVQAQKAGKALVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQNA
VVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNQNVVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTVADEK
SPSRHEGQKGARA

Sequences:

>Translated_413_residues
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAPHTAAAGRRGMRDAPLAPVQAATATTQAVPRYLSGLGT
VTAANTVTVRSRVDGQLIALHFQEGQQVNTGDLLAQIDPSQFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVS
RQELDAQQALVNETQGTIKADEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
ESDIATVVQAQKAGKALVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQNA
VVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNQNVVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTVADEK
SPSRHEGQKGARA
>Mature_413_residues
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAPHTAAAGRRGMRDAPLAPVQAATATTQAVPRYLSGLGT
VTAANTVTVRSRVDGQLIALHFQEGQQVNTGDLLAQIDPSQFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVS
RQELDAQQALVNETQGTIKADEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
ESDIATVVQAQKAGKALVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQNA
VVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNQNVVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTVADEK
SPSRHEGQKGARA

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=415, Percent_Identity=82.4096385542169, Blast_Score=664, Evalue=0.0,
Organism=Escherichia coli, GI1789929, Length=312, Percent_Identity=30.1282051282051, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789665, Length=321, Percent_Identity=29.9065420560748, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1786668, Length=322, Percent_Identity=30.1242236024845, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87081951, Length=122, Percent_Identity=38.5245901639344, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081796, Length=315, Percent_Identity=26.031746031746, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44051; Mature: 44051

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAPHTAAAGRRGMRDAPLAP
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
VQAATATTQAVPRYLSGLGTVTAANTVTVRSRVDGQLIALHFQEGQQVNTGDLLAQIDPS
CHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEECHH
QFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVSRQELDAQQALVNETQGTIKA
HHHEEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEE
DEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
CCCCEEEEEEEEEHHHEECCCCCCCCCEEECCCCCCCCCCCCEEEEEEECCCEEEEEECC
ESDIATVVQAQKAGKALVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDD
CCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCC
TLFPNQFVNARMLVDTEQNAVVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNQN
CCCCCHHCCEEEEEECCCCEEEEEHHHEEECCCCCEEEEECCCCCCCEEEEEEEEECCCC
VVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTVADEKSPSRHEGQKGARA
EEEEECCCCCCEEHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHCCCCCCCC
>Mature Secondary Structure
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAPHTAAAGRRGMRDAPLAP
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
VQAATATTQAVPRYLSGLGTVTAANTVTVRSRVDGQLIALHFQEGQQVNTGDLLAQIDPS
CHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEECHH
QFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVSRQELDAQQALVNETQGTIKA
HHHEEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEE
DEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
CCCCEEEEEEEEEHHHEECCCCCCCCCEEECCCCCCCCCCCCEEEEEEECCCEEEEEECC
ESDIATVVQAQKAGKALVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDD
CCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCC
TLFPNQFVNARMLVDTEQNAVVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNQN
CCCCCHHCCEEEEEECCCCEEEEEHHHEEECCCCCEEEEECCCCCCCEEEEEEEEECCCC
VVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTVADEKSPSRHEGQKGARA
EEEEECCCCCCEEHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA