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The map label for this gene is yedW [H]

Identifier: 194734514

GI number: 194734514

Start: 1142308

End: 1142988

Strand: Reverse

Name: yedW [H]

Synonym: SeSA_A1160

Alternate gene names: 194734514

Gene position: 1142988-1142308 (Counterclockwise)

Preceding gene: 194735731

Following gene: 194738326

Centisome position: 24.27

GC content: 51.54

Gene sequence:

>681_bases
ATGAAGATTTTATTGATTGAAGATAACCAGAAAACCATTGAGTGGGTACGTCAGGGACTCACGGAGGCAGGCTATGTGGT
TGATTATGCCTGTGATGGACGAGACGGATTACACCTGGCCCTTCAGGAACATTATTCATTGATTATTCTTGATATTATGC
TGCCGGGGCTTGATGGATGGCAGGTTTTACGCGCGTTACGCACTGCGCATCAATCCCCTGTTATTTGCCTGACGGCGCGC
GACTCGGTTGAGGATCGCGTCAAAGGTCTTGAGGCGGGCGCTAATGATTACCTTGTTAAGCCTTTTTCCTTCGCCGAACT
GCTGGCCCGGGTGAGAGCTCAACTCAGACAGCACGTCCCGGTCTTTACCCGACTGACGATCAATGGTCTGGACATGGATG
CCACAAAGCAATCGGTGTCACGAAATGGCAAACCGATTTCCCTGACCCGCAAAGAATTCCTGCTCCTCTGGTTACTGGCC
TCCCGGGCAGGAGAAATTGTGCCCCGAACCGCGATCGCCAGCGAGGTTTGGGGAATTAACTTTGATAGTGAAACCAACAC
CGTTGATGTCGCGATTCGTCGGCTGCGCGCCAAAGTAGACGATCCATTTGAAAAGAAGCTCATCATGACCGTGCGGGGGA
TGGGTTATCGATTACAGGCGGAAACGTCGCAGAATGGTTAA

Upstream 100 bases:

>100_bases
TATCTGGCGCGTCCAGGATTAACCTTACACGGACATGACAATTATGTCATCTTGTTGGAGATTTACGGATTCGCTACCAA
GCCTATGGCATACTGCGTCG

Downstream 100 bases:

>100_bases
GTTATCAATGACGCTGCGCCTGACAATTTCTTTTATCGCCATACTTATCCTCGCCTGTACCGGCATTAGCTGGACGCTCT
ATAACGCGCTGAGCAAAGAA

Product: transcriptional regulatory protein YedW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGWQVLRALRTAHQSPVICLTAR
DSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVPVFTRLTINGLDMDATKQSVSRNGKPISLTRKEFLLLWLLA
SRAGEIVPRTAIASEVWGINFDSETNTVDVAIRRLRAKVDDPFEKKLIMTVRGMGYRLQAETSQNG

Sequences:

>Translated_226_residues
MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGWQVLRALRTAHQSPVICLTAR
DSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVPVFTRLTINGLDMDATKQSVSRNGKPISLTRKEFLLLWLLA
SRAGEIVPRTAIASEVWGINFDSETNTVDVAIRRLRAKVDDPFEKKLIMTVRGMGYRLQAETSQNG
>Mature_226_residues
MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGWQVLRALRTAHQSPVICLTAR
DSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVPVFTRLTINGLDMDATKQSVSRNGKPISLTRKEFLLLWLLA
SRAGEIVPRTAIASEVWGINFDSETNTVDVAIRRLRAKVDDPFEKKLIMTVRGMGYRLQAETSQNG

Specific function: Probable member of a two-component regulatory system yedW/yedV [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=75.4545454545455, Blast_Score=348, Evalue=1e-97,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=52.863436123348, Blast_Score=243, Evalue=8e-66,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=37.7272727272727, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=39.8230088495575, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=36.4864864864865, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.5, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=32.4200913242009, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=33.4841628959276, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=36, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=32.4561403508772, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=32.4561403508772, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=32.15859030837, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=34.6491228070175, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=33.6448598130841, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788713, Length=134, Percent_Identity=35.0746268656716, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=31.0344827586207, Blast_Score=60, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=120, Percent_Identity=28.3333333333333, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25416; Mature: 25416

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGW
CEEEEEECCCHHHHHHHHCCCCCCEEEEEEECCCCCEEHEEHHCCCEEEEEECCCCCCHH
QVLRALRTAHQSPVICLTARDSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVP
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHCCC
VFTRLTINGLDMDATKQSVSRNGKPISLTRKEFLLLWLLASRAGEIVPRTAIASEVWGIN
EEEEEEECCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
FDSETNTVDVAIRRLRAKVDDPFEKKLIMTVRGMGYRLQAETSQNG
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHEECCCCEEEEECCCCCC
>Mature Secondary Structure
MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGW
CEEEEEECCCHHHHHHHHCCCCCCEEEEEEECCCCCEEHEEHHCCCEEEEEECCCCCCHH
QVLRALRTAHQSPVICLTARDSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVP
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHCCC
VFTRLTINGLDMDATKQSVSRNGKPISLTRKEFLLLWLLASRAGEIVPRTAIASEVWGIN
EEEEEEECCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
FDSETNTVDVAIRRLRAKVDDPFEKKLIMTVRGMGYRLQAETSQNG
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]