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The map label for this gene is ydcR [H]

Identifier: 194734457

GI number: 194734457

Start: 1659134

End: 1660558

Strand: Reverse

Name: ydcR [H]

Synonym: SeSA_A1716

Alternate gene names: 194734457

Gene position: 1660558-1659134 (Counterclockwise)

Preceding gene: 194738322

Following gene: 194735825

Centisome position: 35.26

GC content: 52.98

Gene sequence:

>1425_bases
ATGAAAAAATATCAACGTCTGGCGGAGCAAATTAGAGAACAAATCGCCTCTGGCGTTTGGCAGCCCGGCGATCGATTACC
CTCGCTGAGGGAGCAGGTCGCCAGTAGCGGCATGAGTTTTATGACTGTCGGTCATGCGTACCAGTTGCTGGAAAGTCAGG
GACGGATTATCGCCCGTCCGCAATCCGGTTATTATGTCGCGCCGCATCCGGTTTGTCGGTCAGTCGCGACGGCAGCGCAC
GTTATTCGGGATGAAGCCGTAGATATCAATACCTATATTTTTGAGATGCTGCAGGCCAGCCGTGATACCTCAGTGGTGCC
TTTTGCTTCAGCGTTTCCCGATCCGCGTCTGTTTCCCTTGCCGCAATTGAACCGATCTCTGGCGCAGGTCAGTAAAACCG
CGACGGCAATGAGCGTCATCGAAAATTTGCCGCCAGGTAATGCAGAATTGCGCTATGCAATAGCACGCCGTTACGCGCAG
CAGGGGATTACCGTTTCTCCTGACGAGATTGTCATTACCGCCGGCGCGCTGGAAGCGTTGAATCTTAGTTTACAGGCGGT
GACGGCACCGGGAGACTGGGTGGTGGTGGAGAACCCCTGTTTCTACGGTGCGCTACAGGCCCTGGAGCGATTGCGCCTGA
AAGCGTTGTCGATACCCACCGATGTTAAAGAAGGTATCGATCTTATGGCGCTGGAACAAGCGTTACAGGAATATCCGGTG
AAAGCGTGCTGGTTAATGACCAACAGCCAGAATCCGTTAGGGTTCACGCTGAGCGCTGAGAAAAAAGCGCGGCTGGTTGC
GTTACTCACGCACCATAACGTGATGCTAATTGAAGATGATGTTTATAGCGAACTCTACTTTGGCCGCGAGAAACCTCTGC
CCGCCAAAGCATGGGATCGCGACGATACCGTGTTGCATTGTTCGTCTTTTTCCAAATGTCTGGTTCCCGGTTTTCGCATT
GGCTGGGTTGCGGGAGGAAGCCATGCCAGACAAATTCAGCGTTTGCAGTTAATGAGCACATTATCCACCAGTTCCCCCAT
GCAATTGGCGTTAGTGGATTATCTCTCGACACGTCGATATGACGCGCATCTGCGCCGATTGCGAAGGCAGCTTGCCGAAC
GTAAACAGCAAGCCTGGCAAACCCTTTTGCGCCATCTCCCGGCGGAAGTAAAAATTCACCATAACGATAGCGGTTATTTT
CTTTGGCTGGAGCTACCTGAGCAGCTTGATGCCGGTGAACTTAGCGCCAAAGCGCTTGAACACCTTATCAGTATCGCGCC
GGGGAAAATGTTTTCAACGTCCGGCGCCTGGACGCGTTTCTTTCGTTTTAACACCGCATGGCATTGGGGAGAACGGGAAG
AACAGGCCGTAAAACAGCTTGGCAGCCTGATTCGCGAGATGCTGCGCGCTAAAAGCCTTGTGTGA

Upstream 100 bases:

>100_bases
TGTTGGAAAGCACCATAACAGTTAGCAAATCGTTGTTAATTTTAACAACTGATATACACTGCGGTTGCCACCTGCAAGCA
GCGCTCAATGAGAACGAATA

Downstream 100 bases:

>100_bases
GGTGGAATGCGTGTCAGCTCACAACCTGACTAAATTTCCCGAGTGTGCCGGGTGAGCATCTGGCGCGCCGTCTATTTTTA
GGAAAGCGGCGGCCCGTTCG

Product: aminotransferase, classes I and II superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MKKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAPHPVCRSVATAAH
VIRDEAVDINTYIFEMLQASRDTSVVPFASAFPDPRLFPLPQLNRSLAQVSKTATAMSVIENLPPGNAELRYAIARRYAQ
QGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVKEGIDLMALEQALQEYPV
KACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCLVPGFRI
GWVAGGSHARQIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQTLLRHLPAEVKIHHNDSGYF
LWLELPEQLDAGELSAKALEHLISIAPGKMFSTSGAWTRFFRFNTAWHWGEREEQAVKQLGSLIREMLRAKSLV

Sequences:

>Translated_474_residues
MKKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAPHPVCRSVATAAH
VIRDEAVDINTYIFEMLQASRDTSVVPFASAFPDPRLFPLPQLNRSLAQVSKTATAMSVIENLPPGNAELRYAIARRYAQ
QGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVKEGIDLMALEQALQEYPV
KACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCLVPGFRI
GWVAGGSHARQIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQTLLRHLPAEVKIHHNDSGYF
LWLELPEQLDAGELSAKALEHLISIAPGKMFSTSGAWTRFFRFNTAWHWGEREEQAVKQLGSLIREMLRAKSLV
>Mature_474_residues
MKKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAPHPVCRSVATAAH
VIRDEAVDINTYIFEMLQASRDTSVVPFASAFPDPRLFPLPQLNRSLAQVSKTATAMSVIENLPPGNAELRYAIARRYAQ
QGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVKEGIDLMALEQALQEYPV
KACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCLVPGFRI
GWVAGGSHARQIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQTLLRHLPAEVKIHHNDSGYF
LWLELPEQLDAGELSAKALEHLISIAPGKMFSTSGAWTRFFRFNTAWHWGEREEQAVKQLGSLIREMLRAKSLV

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=318, Percent_Identity=26.7295597484277, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI33469970, Length=318, Percent_Identity=26.7295597484277, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4507369, Length=215, Percent_Identity=26.046511627907, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1787710, Length=468, Percent_Identity=87.1794871794872, Blast_Score=836, Evalue=0.0,
Organism=Escherichia coli, GI1790797, Length=467, Percent_Identity=35.117773019272, Blast_Score=295, Evalue=5e-81,
Organism=Escherichia coli, GI1788722, Length=346, Percent_Identity=25.7225433526012, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321236, Length=363, Percent_Identity=22.8650137741047, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21356535, Length=353, Percent_Identity=23.5127478753541, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI18859735, Length=183, Percent_Identity=27.8688524590164, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53272; Mature: 53272

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARP
CCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHCCCEEECC
QSGYYVAPHPVCRSVATAAHVIRDEAVDINTYIFEMLQASRDTSVVPFASAFPDPRLFPL
CCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEHHCCCCCCCCCC
PQLNRSLAQVSKTATAMSVIENLPPGNAELRYAIARRYAQQGITVSPDEIVITAGALEAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCHHHH
NLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVKEGIDLMALEQALQEYPV
CCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHCCC
KACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDR
EEEEEEECCCCCCEEEEECCCCHHEEEEEECCCEEEEECHHHHHHHCCCCCCCCCCCCCC
DDTVLHCSSFSKCLVPGFRIGWVAGGSHARQIQRLQLMSTLSTSSPMQLALVDYLSTRRY
CCCEEEECCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DAHLRRLRRQLAERKQQAWQTLLRHLPAEVKIHHNDSGYFLWLELPEQLDAGELSAKALE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHH
HLISIAPGKMFSTSGAWTRFFRFNTAWHWGEREEQAVKQLGSLIREMLRAKSLV
HHHHHCCCCEEECCCCCEEEEEECCEECCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARP
CCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHCCCEEECC
QSGYYVAPHPVCRSVATAAHVIRDEAVDINTYIFEMLQASRDTSVVPFASAFPDPRLFPL
CCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEHHCCCCCCCCCC
PQLNRSLAQVSKTATAMSVIENLPPGNAELRYAIARRYAQQGITVSPDEIVITAGALEAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCHHHH
NLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVKEGIDLMALEQALQEYPV
CCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHCCC
KACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDR
EEEEEEECCCCCCEEEEECCCCHHEEEEEECCCEEEEECHHHHHHHCCCCCCCCCCCCCC
DDTVLHCSSFSKCLVPGFRIGWVAGGSHARQIQRLQLMSTLSTSSPMQLALVDYLSTRRY
CCCEEEECCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DAHLRRLRRQLAERKQQAWQTLLRHLPAEVKIHHNDSGYFLWLELPEQLDAGELSAKALE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHH
HLISIAPGKMFSTSGAWTRFFRFNTAWHWGEREEQAVKQLGSLIREMLRAKSLV
HHHHHCCCCEEECCCCCEEEEEECCEECCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]