Click here to switch to the map view.

The map label for this gene is uxaC

Identifier: 194734239

GI number: 194734239

Start: 3204352

End: 3205764

Strand: Direct

Name: uxaC

Synonym: SeSA_A3319

Alternate gene names: 194734239

Gene position: 3204352-3205764 (Clockwise)

Preceding gene: 194734152

Following gene: 194734333

Centisome position: 68.05

GC content: 53.72

Gene sequence:

>1413_bases
ATGGCTACGTTTATGACTGAAGATTTTCTACTTAAAAACGACATTGCCCGCACGCTGTACCATAAATACGCCGCGCCCAT
GCCGATTTATGACTTCCACTGCCATTTAAGTCCGCAGGAAATCGCCGACGATCGCCGTTTCGATAACCTCGGTCAGATCT
GGCTGGAAGGCGACCACTATAAATGGCGAGCGCTACGAAGCGCAGGCGTGGATGAGTCGCTGATCACCGGCAAAGAGACC
AGCGATTATGAAAAATATATGGCCTGGGCCAATACCGTACCAAAAACGCTGGGCAATCCGCTGTATCACTGGACGCACCT
TGAACTACGCCGTCCATTTGGCATTACAGGTACGCTGTTCGGACCGGATACCGCGGAAAGTATCTGGACGCAGTGTAATG
AGAAACTGGCGACGCCGGCCTTTTCCGCGCGCGGTATTATGCAGCAGATGAATGTGCGGATGGTCGGAACCACCGACGAC
CCGATAGATTCTCTGGAATATCACCGCCAGATAGCCGCCGACGACAGCATTGATATTGAAGTCGCGCCAAGCTGGCGCCC
CGACAAAGTTTTCAAAATCGAACTGGACGGCTTTGTCGATTACCTGAGGAAACTGGAAGCGGCGGCAGATGTCAGCATTA
CCCGTTTCGACGATTTACGTCAGGCGCTCACTCGCCGTCTCGACCATTTCGCCGCCTGCGGCTGTCGCGCGTCCGATCAT
GGCATTGAAACGCTGCGATTTGCGCCGGTGCCCGACGACGCGCAGCTTGACGCCATTCTGGGCAAACGTCTGGCTGGCGA
AACGTTGAGCGAACTTGAGATCGCCCAGTTTACCACGGCGGTGCTGGTCTGGCTGGGCCGTCAGTACGCCGCGCGCGGCT
GGGTGATGCAGCTACATATTGGCGCGATCCGTAATAATAATACCCGTATGTTCCGCCTGCTGGGGCCGGATACCGGCTTT
GACTCCATTGGCGATAATAACATTAGCTGGGCGCTCTCCCGTTTGCTCGACAGTATGGATGTGACCAATGAACTGCCCAA
GACTATCCTCTATTGCCTGAACCCACGTGATAACGAAGTCCTGGCGACCATGATCGGTAACTTCCAGGGGCCGGGAATTG
CCGGAAAAGTGCAGTTTGGTTCCGGCTGGTGGTTTAACGATCAGAAAGACGGGATGCTGCGCCAATTGGAGCAACTGTCG
CAAATGGGCCTGTTAAGTCAGTTTGTCGGGATGCTGACCGACTCCCGCAGTTTCCTTTCTTATACGCGACATGAATATTT
CCGTCGTATTCTCTGTAACCTGCTGGGACAGTGGGCGCAGGACGGAGAGATTCCTGATGATGAAGCGATGCTAAGCCGTA
TGGTTCAGGATATCTGCTTCAATAATGCCCAACGTTATTTCACGATTAAATAA

Upstream 100 bases:

>100_bases
ACCACGAATTTGTGCAAGCCGTTACCGACGCTTACCAACAGCTATTGCAGAACGGCGCGAAAGCCACGGTAGAAGCGCTG
GCTAAGTAAGGAGATAAATC

Downstream 100 bases:

>100_bases
TCGCTATTAATCTGTGAGCACAGGTTTCAGGTATTCCGAGGGGCAGGAAGGCGGTAAGAGAGTGAGAAATTTAGCAGTAA
CGCACTTTTCCAGCCAAAGT

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKET
SDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDD
PIDSLEYHRQIAADDSIDIEVAPSWRPDKVFKIELDGFVDYLRKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDH
GIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGF
DSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLS
QMGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK

Sequences:

>Translated_470_residues
MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKET
SDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDD
PIDSLEYHRQIAADDSIDIEVAPSWRPDKVFKIELDGFVDYLRKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDH
GIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGF
DSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLS
QMGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK
>Mature_469_residues
ATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKETS
DYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDDP
IDSLEYHRQIAADDSIDIEVAPSWRPDKVFKIELDGFVDYLRKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDHG
IETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGFD
SIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLSQ
MGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family

Homologues:

Organism=Escherichia coli, GI2367192, Length=470, Percent_Identity=67.0212765957447, Blast_Score=664, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXAC_SALA4 (B5F623)

Other databases:

- EMBL:   CP001138
- RefSeq:   YP_002148057.1
- ProteinModelPortal:   B5F623
- SMR:   B5F623
- PRIDE:   B5F623
- GeneID:   6794873
- GenomeReviews:   CP001138_GR
- KEGG:   sea:SeAg_B3309
- HOGENOM:   HBG297087
- OMA:   AWAKTVP
- ProtClustDB:   PRK02925
- HAMAP:   MF_00675
- InterPro:   IPR003766
- InterPro:   IPR023177
- Gene3D:   G3DSA:1.10.2020.10

Pfam domain/function: PF02614 UxaC

EC number: =5.3.1.12

Molecular weight: Translated: 53610; Mature: 53479

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHY
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCEEECCCCH
KWRALRSAGVDESLITGKETSDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLF
HHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEC
GPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDDPIDSLEYHRQIAADDSIDIE
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCEEE
VAPSWRPDKVFKIELDGFVDYLRKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDH
ECCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHI
CCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
GAIRNNNTRMFRLLGPDTGFDSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEV
EEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHH
LATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLSQMGLLSQFVGMLTDSRSFLS
HHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure 
ATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHY
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCEEECCCCH
KWRALRSAGVDESLITGKETSDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLF
HHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEC
GPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDDPIDSLEYHRQIAADDSIDIE
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCEEE
VAPSWRPDKVFKIELDGFVDYLRKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDH
ECCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHI
CCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
GAIRNNNTRMFRLLGPDTGFDSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEV
EEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHH
LATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLSQMGLLSQFVGMLTDSRSFLS
HHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA