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The map label for this gene is arrD [H]

Identifier: 194734222

GI number: 194734222

Start: 618243

End: 618740

Strand: Direct

Name: arrD [H]

Synonym: SeSA_A0629

Alternate gene names: 194734222

Gene position: 618243-618740 (Clockwise)

Preceding gene: 194737543

Following gene: 194738299

Centisome position: 13.13

GC content: 49.6

Gene sequence:

>498_bases
ATGAACAGCACCCTTCGAAAAAGCGTACTGGCAGCCGTTGGTGGTGGGGCTATCGCAATAGCTTCTGCACTGATTACTGG
GCCAACTGGTAATGATGGTCTGGAAGGTGTCAGCTACATACCATACAAAGATATTGTTGGTGTATGGACTGTATGTCACG
GACACACCGGAAAAGACATCATGCTCGGTAAAACGTATACCGAAGCAGAATGCAAAGCCCTCCTGAATAAAGACCTTGCC
ACGGTCGCCAGACAAATTAACCCGTACATTAAAGTCGATATACCGGAAACAACGCGCGGCGCTCTTTACTCGTTCGTCTA
CAACGTGGGTGCTGGCAATTTCAGAACATCGACGCTTCTTCGCAAAATAAACCAGGGCGATATCAAAGGCGCATGTGATC
AGATACGGCGCTGGACATACGCTGGCGGTAAGCAATGGAAAGGGCTGATGACTCGCCGTGAGATTGAGCGTGAAGTCTGT
TTGTGGGGGCAGCAATGA

Upstream 100 bases:

>100_bases
AGATACTGCAGGACATTTTGAATAAAACCGACTCCAGAAATCCATCAGCTACAGCCACGGTTATCGCCGAACTCGGTCAG
AAAGCACCAAAGGAAATCTG

Downstream 100 bases:

>100_bases
GCATGATTTGCTTTTTCATGGCAGCGTTGCTCGCATTCAATGGCAACGATGCGTGGCCGTGGTTTCTGGCCGTTGGGGTG
TTGATGTCATGAGTCGGTTA

Product: phage lysozyme

Products: NA

Alternate protein names: Endolysin; Lysis protein; Muramidase [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MNSTLRKSVLAAVGGGAIAIASALITGPTGNDGLEGVSYIPYKDIVGVWTVCHGHTGKDIMLGKTYTEAECKALLNKDLA
TVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLLRKINQGDIKGACDQIRRWTYAGGKQWKGLMTRREIEREVC
LWGQQ

Sequences:

>Translated_165_residues
MNSTLRKSVLAAVGGGAIAIASALITGPTGNDGLEGVSYIPYKDIVGVWTVCHGHTGKDIMLGKTYTEAECKALLNKDLA
TVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLLRKINQGDIKGACDQIRRWTYAGGKQWKGLMTRREIEREVC
LWGQQ
>Mature_165_residues
MNSTLRKSVLAAVGGGAIAIASALITGPTGNDGLEGVSYIPYKDIVGVWTVCHGHTGKDIMLGKTYTEAECKALLNKDLA
TVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLLRKINQGDIKGACDQIRRWTYAGGKQWKGLMTRREIEREVC
LWGQQ

Specific function: Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity [H]

COG id: COG3772

COG function: function code R; Phage-related lysozyme (muraminidase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 24 family [H]

Homologues:

Organism=Escherichia coli, GI1786768, Length=165, Percent_Identity=93.9393939393939, Blast_Score=302, Evalue=7e-84,
Organism=Escherichia coli, GI1787836, Length=184, Percent_Identity=32.6086956521739, Blast_Score=77, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002196 [H]

Pfam domain/function: PF00959 Phage_lysozyme [H]

EC number: =3.2.1.17 [H]

Molecular weight: Translated: 18024; Mature: 18024

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTLRKSVLAAVGGGAIAIASALITGPTGNDGLEGVSYIPYKDIVGVWTVCHGHTGKDI
CCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEE
MLGKTYTEAECKALLNKDLATVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLL
EECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHH
RKINQGDIKGACDQIRRWTYAGGKQWKGLMTRREIEREVCLWGQQ
HHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNSTLRKSVLAAVGGGAIAIASALITGPTGNDGLEGVSYIPYKDIVGVWTVCHGHTGKDI
CCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEE
MLGKTYTEAECKALLNKDLATVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLL
EECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHH
RKINQGDIKGACDQIRRWTYAGGKQWKGLMTRREIEREVCLWGQQ
HHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]