| Definition | Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome. |
|---|---|
| Accession | NC_011094 |
| Length | 4,709,075 |
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The map label for this gene is ligA [H]
Identifier: 194734182
GI number: 194734182
Start: 2541837
End: 2543852
Strand: Reverse
Name: ligA [H]
Synonym: SeSA_A2662
Alternate gene names: 194734182
Gene position: 2543852-2541837 (Counterclockwise)
Preceding gene: 194738121
Following gene: 194734557
Centisome position: 54.02
GC content: 56.89
Gene sequence:
>2016_bases ATGGAACCAATCGAACAACAACTGACAGAACTGCGAACCACGCTTCGCCATCATGAATATCTGTATCATGTGATGGATGC GCCGGAGATTCCCGACGCCGAATATGACCGCCTGATGCGGGAACTGCGAGAGCTGGAGGCGCAACGTCCGGACCTTATCA CGCCGGATTCGCCCACGCAGCGCGTTGGCGCGGCGCCGCTGACGGCATTCAACCAGATTCGCCATGAAGTACCGATGCTG TCGCTCGATAACGTATTTGATGAAGAAAGCTTCCTGGCGTTTAACAAGCGAGTGCAGGATCGTCTAAAAAGCACGGAAAA TGTCATCTGGTGCTGCGAGCTAAAACTGGATGGCCTGGCGGTCAGCATTCTGTATGAAAACGGCGTGCTGGTGAGCGCTG CGACGCGTGGCGACGGCACCACCGGTGAAGATATCACTTCAAACGTGCGCACGATTCGTGCCATTCCTTTAAAGCTGCAT GGCGATAACATTCCGGCGCGTCTTGAAGTTCGCGGAGAGGTATTTTTACCGCAGGCCGGGTTCGAAAAGATCAATGAAGA CGCGCGCCGTACTGGCGGCAAAGTGTTTGCTAACCCGCGTAACGCGGCGGCGGGCTCGCTGCGTCAGCTCGATCCGCGTA TTACGGCGAAGCGACCACTAACATTTTTCTGCTACGGCGTCGGTATTCTGGAAGGCGGCGAGTTGCCGGATACGCATCTG GGACGTTTGCTGCAATTTAAAGCGTGGGGGCTACCGGTCAGCGATCGCGTGACGCTGTGCGATTCTCCCCAGGCGGTACT GGATTTTTATCACAACGTCGAAAAAGATCGCCCCACGCTCGGTTTTGATATCGACGGCGTGGTGATTAAGGTCAACTCGC TGGCTTTGCAGGAACAGCTGGGCTTTGTGGCCCGCGCGCCGCGCTGGGCGGTGGCGTTTAAATTCCCTGCTCAGGAGCAG ATGACTTTTGTGCGCGATGTTGAGTTTCAGGTCGGGCGCACCGGGGCGATTACGCCGGTGGCGCGTCTGGAACCAGTTCA GGTGGCTGGTGTGCTGGTCAGCAATGCCACGTTGCATAATGCCGATGAAATTGAACGGCTTGGCTTGCGTATTGGCGATA AGGTGGTTATCCGTCGGGCAGGCGATGTGATCCCTCAGGTGGTCAACGTGGTTCTGTCCGAACGCCCTGAAGAGACGCGT CCGATTGTGTTTCCAACGCACTGTCCGGTGTGCGGATCGGACGTAGAGCGCGTTGAAGGCGAAGCCGTTACCCGTTGTAC CGGCGGGCTGATTTGCGGCGCGCAGCGTAAAGAGTCGCTGAAACATTTTGTGTCGCGCCGGGCGATGGATGTAGACGGGA TGGGCGATAAGATCATCGACCAACTGGTGGAAAGGGAGTATGTCCATACGCCAGCGGATCTGTTCCGTCTGACGGCGGGT AAACTGACCGGCCTGGACCGAATGGGGCCAAAGTCCGCGCAAAATGTTGTAAACGCGCTGGAAAAAGCCAAAGCGACGAC CTTTGCGCGTTTTCTCTATGCGCTGGGCATCCGTGAAGTGGGTGAGGCGACGGCGGCGGGGCTGGCGGCTTATTTCGGCA CGTTGGAGGCGCTGCAGGCCGCCACCATTGACGAGTTGCAGAAAGTGCCTGACGTGGGGATTGTTGTCGCTACGCACGTC TTTAACTTTTTTGCCGAAGAGAGTAATCGTGACGTGATTGGGCAGCTACTGGCGGAAGGGGTTCACTGGCCCGCGCCGGT AGTCATTAATGTGCAAGAGATCGATAGCCCGTTTGCCGGTAAAACCGTGGTACTAACCGGTAGCCTGAGCCAGATGTCCC GCGATGACGCTAAAGCGCGTTTAGTGGCGCTGGGCGCGAAAGTGGCAGGCAGCGTATCGAAGAAAACCGATCTGGTGATT GCCGGTGAAGCGGCGGGTTCCAAACTGACCAAAGCGCAGGAACTGGGTATTACCGTGATTGATGAAGCGGAAATGATCCG CTTACTGGATGCCTGA
Upstream 100 bases:
>100_bases TCCGCGAGGTGATGGACGCTAACGCCTGAGGTTAACGCAGGTGTGACATTTTTAACGTAACCCCCGCCTGTCGGGGGTTT TTTATCATTGATGGTGTGAT
Downstream 100 bases:
>100_bases GATGGAAAAAGAGCAGCTGGTTGAAATCGCCAACACCGTGATGCCGTTCGGCAAATATCAGGGACGTCGATTGATCGACC TTCCGGAAGAGTATTTGCTG
Product: NAD-dependent DNA ligase LigA
Products: NA
Alternate protein names: Polydeoxyribonucleotide synthase [NAD+] [H]
Number of amino acids: Translated: 671; Mature: 671
Protein sequence:
>671_residues MEPIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAQRPDLITPDSPTQRVGAAPLTAFNQIRHEVPML SLDNVFDEESFLAFNKRVQDRLKSTENVIWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH GDNIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHL GRLLQFKAWGLPVSDRVTLCDSPQAVLDFYHNVEKDRPTLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQ MTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETR PIVFPTHCPVCGSDVERVEGEAVTRCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEREYVHTPADLFRLTAG KLTGLDRMGPKSAQNVVNALEKAKATTFARFLYALGIREVGEATAAGLAAYFGTLEALQAATIDELQKVPDVGIVVATHV FNFFAEESNRDVIGQLLAEGVHWPAPVVINVQEIDSPFAGKTVVLTGSLSQMSRDDAKARLVALGAKVAGSVSKKTDLVI AGEAAGSKLTKAQELGITVIDEAEMIRLLDA
Sequences:
>Translated_671_residues MEPIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAQRPDLITPDSPTQRVGAAPLTAFNQIRHEVPML SLDNVFDEESFLAFNKRVQDRLKSTENVIWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH GDNIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHL GRLLQFKAWGLPVSDRVTLCDSPQAVLDFYHNVEKDRPTLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQ MTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETR PIVFPTHCPVCGSDVERVEGEAVTRCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEREYVHTPADLFRLTAG KLTGLDRMGPKSAQNVVNALEKAKATTFARFLYALGIREVGEATAAGLAAYFGTLEALQAATIDELQKVPDVGIVVATHV FNFFAEESNRDVIGQLLAEGVHWPAPVVINVQEIDSPFAGKTVVLTGSLSQMSRDDAKARLVALGAKVAGSVSKKTDLVI AGEAAGSKLTKAQELGITVIDEAEMIRLLDA >Mature_671_residues MEPIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAQRPDLITPDSPTQRVGAAPLTAFNQIRHEVPML SLDNVFDEESFLAFNKRVQDRLKSTENVIWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH GDNIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHL GRLLQFKAWGLPVSDRVTLCDSPQAVLDFYHNVEKDRPTLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQ MTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETR PIVFPTHCPVCGSDVERVEGEAVTRCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEREYVHTPADLFRLTAG KLTGLDRMGPKSAQNVVNALEKAKATTFARFLYALGIREVGEATAAGLAAYFGTLEALQAATIDELQKVPDVGIVVATHV FNFFAEESNRDVIGQLLAEGVHWPAPVVINVQEIDSPFAGKTVVLTGSLSQMSRDDAKARLVALGAKVAGSVSKKTDLVI AGEAAGSKLTKAQELGITVIDEAEMIRLLDA
Specific function: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of dam
COG id: COG0272
COG function: function code L; NAD-dependent DNA ligase (contains BRCT domain type II)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 BRCT domain [H]
Homologues:
Organism=Escherichia coli, GI1788750, Length=669, Percent_Identity=93.1240657698057, Blast_Score=1281, Evalue=0.0, Organism=Escherichia coli, GI87082305, Length=587, Percent_Identity=22.9982964224872, Blast_Score=99, Evalue=7e-22,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001357 - InterPro: IPR018239 - InterPro: IPR004150 - InterPro: IPR001679 - InterPro: IPR013839 - InterPro: IPR013840 - InterPro: IPR003583 - InterPro: IPR012340 - InterPro: IPR016027 - InterPro: IPR010994 - InterPro: IPR004149 [H]
Pfam domain/function: PF00533 BRCT; PF01653 DNA_ligase_aden; PF03120 DNA_ligase_OB; PF03119 DNA_ligase_ZBD [H]
EC number: =6.5.1.2 [H]
Molecular weight: Translated: 73510; Mature: 73510
Theoretical pI: Translated: 5.38; Mature: 5.38
Prosite motif: PS50172 BRCT ; PS01055 DNA_LIGASE_N1 ; PS01056 DNA_LIGASE_N2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEPIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAQRPDLITPDSPTQ CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHH RVGAAPLTAFNQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSTENVIWCCELKLDGLA HCCCCHHHHHHHHHHHCCCEEHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCEE VSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGDNIPARLEVRGEVFLPQAG EEEEEECCEEEEEECCCCCCCCHHHHHCCEEEEEEEEEEECCCCCEEEEECCEEECCCCC FEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHL HHHHHHHHHHCCCEEEECCCCCCCCCHHHCCCCCCCCCCEEEEEEEEEEECCCCCCHHHH GRLLQFKAWGLPVSDRVTLCDSPQAVLDFYHNVEKDRPTLGFDIDGVVIKVNSLALQEQL HHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHH GFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHN HHHHCCCCEEEEEECCCHHHHHHHHHCHHCCCCCCCCCCHHHCCCHHEEEEEEECCCCCC ADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETRPIVFPTHCPVCGSDVERVEG HHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHCC EAVTRCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEREYVHTPADLFRLTAG CHHHHHCCCEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH KLTGLDRMGPKSAQNVVNALEKAKATTFARFLYALGIREVGEATAAGLAAYFGTLEALQA HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH ATIDELQKVPDVGIVVATHVFNFFAEESNRDVIGQLLAEGVHWPAPVVINVQEIDSPFAG HHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEHHHCCCCCCC KTVVLTGSLSQMSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLTKAQELGITVI CEEEEECCHHHHHHHHHHHHHHEECHHHHCCCCCCCCEEEEECCCCCHHHHHHHCCEEEE DEAEMIRLLDA CHHHHHHHHCC >Mature Secondary Structure MEPIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAQRPDLITPDSPTQ CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHH RVGAAPLTAFNQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSTENVIWCCELKLDGLA HCCCCHHHHHHHHHHHCCCEEHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCEE VSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGDNIPARLEVRGEVFLPQAG EEEEEECCEEEEEECCCCCCCCHHHHHCCEEEEEEEEEEECCCCCEEEEECCEEECCCCC FEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHL HHHHHHHHHHCCCEEEECCCCCCCCCHHHCCCCCCCCCCEEEEEEEEEEECCCCCCHHHH GRLLQFKAWGLPVSDRVTLCDSPQAVLDFYHNVEKDRPTLGFDIDGVVIKVNSLALQEQL HHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHH GFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHN HHHHCCCCEEEEEECCCHHHHHHHHHCHHCCCCCCCCCCHHHCCCHHEEEEEEECCCCCC ADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETRPIVFPTHCPVCGSDVERVEG HHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHCC EAVTRCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEREYVHTPADLFRLTAG CHHHHHCCCEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH KLTGLDRMGPKSAQNVVNALEKAKATTFARFLYALGIREVGEATAAGLAAYFGTLEALQA HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH ATIDELQKVPDVGIVVATHVFNFFAEESNRDVIGQLLAEGVHWPAPVVINVQEIDSPFAG HHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEHHHCCCCCCC KTVVLTGSLSQMSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLTKAQELGITVI CEEEEECCHHHHHHHHHHHHHHEECHHHHCCCCCCCCEEEEECCCCCHHHHHHHCCEEEE DEAEMIRLLDA CHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA