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The map label for this gene is sotB [H]

Identifier: 194734140

GI number: 194734140

Start: 1566363

End: 1567553

Strand: Reverse

Name: sotB [H]

Synonym: SeSA_A1627

Alternate gene names: 194734140

Gene position: 1567553-1566363 (Counterclockwise)

Preceding gene: 194738004

Following gene: 194736236

Centisome position: 33.29

GC content: 53.06

Gene sequence:

>1191_bases
ATGACAATCAATCCAGTTTCCCGCAAGGTCGCGTGGCTACGGGTAGTTACGCTTGCTATTGCCGCTTTTATTTTCAATAC
CACAGAATTTGTGCCGGTTGGTTTGCTATCAGACATTGCTGAAAGCTTTCATATGCAAACCGCGCAGGTCGGCATCATGC
TAACCATTTACGCCTGGGTAGTTGCCGTCATGTCGCTGCCTTTTATGCTTCTTACCAGTCAAATGGAGCGCCGTAAGCTA
CTCATTTGTCTGTTTGTTTTGTTTATTGCCAGCCATGTGCTCTCCTTTCTGGCATGGAACTTTACCGTGCTGGTCATTAG
CCGTATTGGCATCGCTTTCGCCCACGCTATTTTCTGGTCGATAACCGCCTCGCTGGCGATCCGCCTGGCCCCTGCCGGGA
AACGCGCGCAGGCATTAAGTCTGATAGCGACCGGCACCGCGTTGGCCATGGTGCTTGGGCTGCCGATAGGTCGCGTTGTT
GGTCAGTATTTTGGCTGGCGCACCACCTTTTTTGCCATCGGCATGGGCGCATTAATTACGCTGCTATGTCTGATTAAGCT
TCTACCGAAATTGCCGAGCGAGCATTCCGGCTCACTAAAAAGTTTACCTTTGCTATTCCGACGCCCGGCGCTGATGAGCC
TCTATGTACTGACCGTCGTTGTGGTGACTGCGCATTACACCGCTTATAGCTATATTGAACCGTTCGTTCAGAATGTCGCC
GGGCTCAGTGCGAATTTTGCTACCGTCCTGTTACTGATCCTCGGCGGCGCCGGGATCATCGGCAGCCTTGTGTTTGGTAA
ACTGGGTAATCGCCATGCCTCGTCGCTCGTCAGTATCGCTATTGCCCTGCTGGTTATCTGTCTGCTTCTGCTGCTGCCTG
CGGCGAATAGCGAAGCGCATCTGGCCATACTGAGCATTTTCTGGGGCATTGCGATTATGGTGATAGGGCTCGGTATGCAG
GTGAAAGTACTGGCGCTGGCCCCGGACGCGACCGATGTCGCAATGGCGCTATTTTCAGGCATCTTTAATATTGGTATTGG
CGCTGGCGCGCTGGTAGGCAATCAGGTGAGTTTGCACTGGTCAATGTCGGCCATCGGCTATATTGGCGCTATACCCGCCT
GTGCCGCGCTGGTATGGGCTGTGCTCATATTCCGCAAATGGCCAGTGACGCTGGAAGAACAACCGCATTAA

Upstream 100 bases:

>100_bases
CGAAGTAAATGAGAAGCAGGTCACAAAATGATTGTCTTTTCGCCAGTAAACGTTTTAAGATCGCGGTCTCACCTTCTCGC
AACTAACCCGAAATATTTTT

Downstream 100 bases:

>100_bases
GACATTCGTCTGCCGGGAACAGGTTTCCGGCAGACGAAAATGCGCCTTAGTGGTACGTTTTAATAATTTCCAACACGCCG
TTGATAATAAATTGCACGCC

Product: sugar efflux transporter

Products: arabinose [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTINPVSRKVAWLRVVTLAIAAFIFNTTEFVPVGLLSDIAESFHMQTAQVGIMLTIYAWVVAVMSLPFMLLTSQMERRKL
LICLFVLFIASHVLSFLAWNFTVLVISRIGIAFAHAIFWSITASLAIRLAPAGKRAQALSLIATGTALAMVLGLPIGRVV
GQYFGWRTTFFAIGMGALITLLCLIKLLPKLPSEHSGSLKSLPLLFRRPALMSLYVLTVVVVTAHYTAYSYIEPFVQNVA
GLSANFATVLLLILGGAGIIGSLVFGKLGNRHASSLVSIAIALLVICLLLLLPAANSEAHLAILSIFWGIAIMVIGLGMQ
VKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSAIGYIGAIPACAALVWAVLIFRKWPVTLEEQPH

Sequences:

>Translated_396_residues
MTINPVSRKVAWLRVVTLAIAAFIFNTTEFVPVGLLSDIAESFHMQTAQVGIMLTIYAWVVAVMSLPFMLLTSQMERRKL
LICLFVLFIASHVLSFLAWNFTVLVISRIGIAFAHAIFWSITASLAIRLAPAGKRAQALSLIATGTALAMVLGLPIGRVV
GQYFGWRTTFFAIGMGALITLLCLIKLLPKLPSEHSGSLKSLPLLFRRPALMSLYVLTVVVVTAHYTAYSYIEPFVQNVA
GLSANFATVLLLILGGAGIIGSLVFGKLGNRHASSLVSIAIALLVICLLLLLPAANSEAHLAILSIFWGIAIMVIGLGMQ
VKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSAIGYIGAIPACAALVWAVLIFRKWPVTLEEQPH
>Mature_395_residues
TINPVSRKVAWLRVVTLAIAAFIFNTTEFVPVGLLSDIAESFHMQTAQVGIMLTIYAWVVAVMSLPFMLLTSQMERRKLL
ICLFVLFIASHVLSFLAWNFTVLVISRIGIAFAHAIFWSITASLAIRLAPAGKRAQALSLIATGTALAMVLGLPIGRVVG
QYFGWRTTFFAIGMGALITLLCLIKLLPKLPSEHSGSLKSLPLLFRRPALMSLYVLTVVVVTAHYTAYSYIEPFVQNVAG
LSANFATVLLLILGGAGIIGSLVFGKLGNRHASSLVSIAIALLVICLLLLLPAANSEAHLAILSIFWGIAIMVIGLGMQV
KVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSAIGYIGAIPACAALVWAVLIFRKWPVTLEEQPH

Specific function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family [H]

Homologues:

Organism=Escherichia coli, GI1787808, Length=396, Percent_Identity=87.8787878787879, Blast_Score=633, Evalue=0.0,
Organism=Escherichia coli, GI1787947, Length=375, Percent_Identity=31.2, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI145693198, Length=344, Percent_Identity=27.0348837209302, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786595, Length=343, Percent_Identity=22.1574344023324, Blast_Score=98, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42421; Mature: 42290

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TINPVSRKVAWLRVVTLAIAAFIFNTTEFVPVGLLSDIAESFHMQTAQVGIMLTIYAWV
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAVMSLPFMLLTSQMERRKLLICLFVLFIASHVLSFLAWNFTVLVISRIGIAFAHAIFWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITASLAIRLAPAGKRAQALSLIATGTALAMVLGLPIGRVVGQYFGWRTTFFAIGMGALIT
HHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLCLIKLLPKLPSEHSGSLKSLPLLFRRPALMSLYVLTVVVVTAHYTAYSYIEPFVQNVA
HHHHHHHHHCCCCCCCCCCHHCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLSANFATVLLLILGGAGIIGSLVFGKLGNRHASSLVSIAIALLVICLLLLLPAANSEAH
CCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LAILSIFWGIAIMVIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHW
HHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEE
SMSAIGYIGAIPACAALVWAVLIFRKWPVTLEEQPH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: arabinose [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: arabinose [Cytoplasm] + Proton [Periplasm] = arabinose [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA