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The map label for this gene is ylaB [H]

Identifier: 194734105

GI number: 194734105

Start: 532705

End: 534255

Strand: Reverse

Name: ylaB [H]

Synonym: SeSA_A0528

Alternate gene names: 194734105

Gene position: 534255-532705 (Counterclockwise)

Preceding gene: 194734753

Following gene: 194735636

Centisome position: 11.35

GC content: 51.84

Gene sequence:

>1551_bases
GTGACAACACGACATCTGGTCAGCCTGGTAACGGGAGTGCTTATCCTGTCTGTCCTTTTCCCGATAGGATTGAGTCTGTG
GCTGGCGCACCGTCAAGTTGAAAAAAGGTTTAACGAAGAGCTGGATATCTTCTCGTCCCGGGTGGCGCTACGTACAGAAA
GGGTCAGTGACCAGGCAAAAGCCGCGTTAACGCATATTGCCTCCTTTAAAGGCGAGCCCTGCAGCAGCGCCCATTTACTC
GCCATGCGCCGCGTGTCTTATAGCTTTCGGTATGTCCAGGAAGTTCTGTATCTTAAAAATTCGATTCCCGTTTGCTCCTC
ACTTGAAAAAGAGAGCCATATTCCCGCTTTCCCTCCGCCCATGAAAATCACTCGCGACGGTTATCGCGCCTGGTTTACGG
CGCAAAACGATCTGGGTATAAAACGCTATATGGCGGCACTCGGGAGCGACAGCTATATCGTGATGATCGACCCGGCGTCC
TTTATCGATGTGATTCCGTTTGGCGCATGGCCGATTGACGTCGCTATTATTGGCCGGGAACGCAATACTGTGGTTGCCAG
CAGCGGTAACCTTGACCTCGCTATTCTTCCGCTCATTCACCATGAGACGCCCCTGCGGCTGGAAAACCGAGGCATTCAGT
ATGCTATTCACCCCTTTCCGGAAATGGGCATTACTATCGTAAGCTGGGCACCGACCGCTCCGCTGGAAAGGAGCTGGTAT
CGACAGGCATTTATCTGGCTACCGGCGGGCATCGTAACGGGTCTGCTGGCTGCGGCCTTTATTCTGCGTATTTTGCGTCG
GCTACAGTCGCCCCGCCACCGTCTCCAGGATGCGATAGACAATCGCGAAATTAACGTACACTATCAGCCTATTGTCTCCC
TGAGCAGCGGAAAAATTGTCGGTGCCGAAGCTTTAGCTCGCTGGCAACAGGCGGACGGCACCTTCCTTTCGCCGGAAATT
TTTATCGCGCTGGCTGAACAAACCGGGCTCACAGAGCCGCTAACCCGGCTAATCATCGACACCGTTTTTGAAGACATGGG
GAGTTGGTTAAAGTCCCATCCCGAACAACATATTTCAATCAATCTTGAGGCATCCGATCTGGCGTCGGAAACGTTGCCGA
CGCTGTTAAGCACGCTGCTGAACCGTAGCCAAATTTCTCCGTCGCAAATCGCGCTTGAGTTAACGGAACGCGAGTTTGCC
GATCCGAAAACCAGCGCGCCCATTGTCGCCAGATACCGTAACGCGGGACATTCCATTTATATTGATGACTTTGGCACCGG
CTATTCCAGCCTCAGCTACTTACAAAATCTGGATGTGGATGTCCTTAAAATTGATAAATCTTTTGTCGATGCGCTGGAAT
ATAAAAACGTCACGCCGCATATTATTGAAATGGCGAAAACGCTCAAACTTAAGATGGTCGCAGAAGGCATCGAAACGACC
AGGCAAGAACAGTGGCTACGCCAGCATGGCGTACATTATGGTCAGGGCTGGTTATACAGTAAGCCCCTACCCGCTACGGC
ATTTATTCTTTGGGCGGAACAGCGGCTATAA

Upstream 100 bases:

>100_bases
GCCCCTATATCTGTAAAATCGATAAAATAGCTTTATCATTCGAGGGCGCGATTTACGATCGGATATACTTTCTCTACGCT
GTGTTTATAAGGACATCACT

Downstream 100 bases:

>100_bases
CGTCGCACAGCAGAAAAGAACAGTGTGGAGAGGCACAAATGGGTGGGGGCCCTGCCAGCTACATCCCGGCACACGCGTCA
TCTGCCTTGGCTGCTTCCTT

Product: cyclic diguanylate phosphodiesterase (EAL) domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MTTRHLVSLVTGVLILSVLFPIGLSLWLAHRQVEKRFNEELDIFSSRVALRTERVSDQAKAALTHIASFKGEPCSSAHLL
AMRRVSYSFRYVQEVLYLKNSIPVCSSLEKESHIPAFPPPMKITRDGYRAWFTAQNDLGIKRYMAALGSDSYIVMIDPAS
FIDVIPFGAWPIDVAIIGRERNTVVASSGNLDLAILPLIHHETPLRLENRGIQYAIHPFPEMGITIVSWAPTAPLERSWY
RQAFIWLPAGIVTGLLAAAFILRILRRLQSPRHRLQDAIDNREINVHYQPIVSLSSGKIVGAEALARWQQADGTFLSPEI
FIALAEQTGLTEPLTRLIIDTVFEDMGSWLKSHPEQHISINLEASDLASETLPTLLSTLLNRSQISPSQIALELTEREFA
DPKTSAPIVARYRNAGHSIYIDDFGTGYSSLSYLQNLDVDVLKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETT
RQEQWLRQHGVHYGQGWLYSKPLPATAFILWAEQRL

Sequences:

>Translated_516_residues
MTTRHLVSLVTGVLILSVLFPIGLSLWLAHRQVEKRFNEELDIFSSRVALRTERVSDQAKAALTHIASFKGEPCSSAHLL
AMRRVSYSFRYVQEVLYLKNSIPVCSSLEKESHIPAFPPPMKITRDGYRAWFTAQNDLGIKRYMAALGSDSYIVMIDPAS
FIDVIPFGAWPIDVAIIGRERNTVVASSGNLDLAILPLIHHETPLRLENRGIQYAIHPFPEMGITIVSWAPTAPLERSWY
RQAFIWLPAGIVTGLLAAAFILRILRRLQSPRHRLQDAIDNREINVHYQPIVSLSSGKIVGAEALARWQQADGTFLSPEI
FIALAEQTGLTEPLTRLIIDTVFEDMGSWLKSHPEQHISINLEASDLASETLPTLLSTLLNRSQISPSQIALELTEREFA
DPKTSAPIVARYRNAGHSIYIDDFGTGYSSLSYLQNLDVDVLKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETT
RQEQWLRQHGVHYGQGWLYSKPLPATAFILWAEQRL
>Mature_515_residues
TTRHLVSLVTGVLILSVLFPIGLSLWLAHRQVEKRFNEELDIFSSRVALRTERVSDQAKAALTHIASFKGEPCSSAHLLA
MRRVSYSFRYVQEVLYLKNSIPVCSSLEKESHIPAFPPPMKITRDGYRAWFTAQNDLGIKRYMAALGSDSYIVMIDPASF
IDVIPFGAWPIDVAIIGRERNTVVASSGNLDLAILPLIHHETPLRLENRGIQYAIHPFPEMGITIVSWAPTAPLERSWYR
QAFIWLPAGIVTGLLAAAFILRILRRLQSPRHRLQDAIDNREINVHYQPIVSLSSGKIVGAEALARWQQADGTFLSPEIF
IALAEQTGLTEPLTRLIIDTVFEDMGSWLKSHPEQHISINLEASDLASETLPTLLSTLLNRSQISPSQIALELTEREFAD
PKTSAPIVARYRNAGHSIYIDDFGTGYSSLSYLQNLDVDVLKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETTR
QEQWLRQHGVHYGQGWLYSKPLPATAFILWAEQRL

Specific function: Unknown

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI87081743, Length=516, Percent_Identity=67.4418604651163, Blast_Score=738, Evalue=0.0,
Organism=Escherichia coli, GI1790496, Length=519, Percent_Identity=32.9479768786127, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI87081845, Length=259, Percent_Identity=38.996138996139, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI226510982, Length=237, Percent_Identity=37.1308016877637, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787541, Length=247, Percent_Identity=32.3886639676113, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788502, Length=271, Percent_Identity=32.4723247232472, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1786507, Length=241, Percent_Identity=33.6099585062241, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI87081980, Length=236, Percent_Identity=36.0169491525424, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081921, Length=247, Percent_Identity=35.6275303643725, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1788849, Length=254, Percent_Identity=29.1338582677165, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI87082096, Length=239, Percent_Identity=30.9623430962343, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787055, Length=244, Percent_Identity=29.0983606557377, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787410, Length=249, Percent_Identity=26.9076305220884, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58055; Mature: 57923

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRHLVSLVTGVLILSVLFPIGLSLWLAHRQVEKRFNEELDIFSSRVALRTERVSDQAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALTHIASFKGEPCSSAHLLAMRRVSYSFRYVQEVLYLKNSIPVCSSLEKESHIPAFPPP
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHCCCCCCCCC
MKITRDGYRAWFTAQNDLGIKRYMAALGSDSYIVMIDPASFIDVIPFGAWPIDVAIIGRE
CCEECCCCEEEEEECCCCCHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCEEEEEEEECC
RNTVVASSGNLDLAILPLIHHETPLRLENRGIQYAIHPFPEMGITIVSWAPTAPLERSWY
CCEEEEECCCCCEEEEEEEECCCCCEECCCCCEEEECCCCCCCEEEEEECCCCCCHHHHH
RQAFIWLPAGIVTGLLAAAFILRILRRLQSPRHRLQDAIDNREINVHYQPIVSLSSGKIV
HHHHHEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEEEEEEEEECCCCEE
GAEALARWQQADGTFLSPEIFIALAEQTGLTEPLTRLIIDTVFEDMGSWLKSHPEQHISI
CHHHHHHHHHCCCCEECCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
NLEASDLASETLPTLLSTLLNRSQISPSQIALELTEREFADPKTSAPIVARYRNAGHSIY
EEEHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEHHHHCCCCCCCCCHHHHHHCCCCEEE
IDDFGTGYSSLSYLQNLDVDVLKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETT
EECCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RQEQWLRQHGVHYGQGWLYSKPLPATAFILWAEQRL
HHHHHHHHCCCCCCCCEEECCCCCCEEEEEEECCCC
>Mature Secondary Structure 
TTRHLVSLVTGVLILSVLFPIGLSLWLAHRQVEKRFNEELDIFSSRVALRTERVSDQAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALTHIASFKGEPCSSAHLLAMRRVSYSFRYVQEVLYLKNSIPVCSSLEKESHIPAFPPP
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHCCCCCCCCC
MKITRDGYRAWFTAQNDLGIKRYMAALGSDSYIVMIDPASFIDVIPFGAWPIDVAIIGRE
CCEECCCCEEEEEECCCCCHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCEEEEEEEECC
RNTVVASSGNLDLAILPLIHHETPLRLENRGIQYAIHPFPEMGITIVSWAPTAPLERSWY
CCEEEEECCCCCEEEEEEEECCCCCEECCCCCEEEECCCCCCCEEEEEECCCCCCHHHHH
RQAFIWLPAGIVTGLLAAAFILRILRRLQSPRHRLQDAIDNREINVHYQPIVSLSSGKIV
HHHHHEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEEEEEEEEECCCCEE
GAEALARWQQADGTFLSPEIFIALAEQTGLTEPLTRLIIDTVFEDMGSWLKSHPEQHISI
CHHHHHHHHHCCCCEECCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
NLEASDLASETLPTLLSTLLNRSQISPSQIALELTEREFADPKTSAPIVARYRNAGHSIY
EEEHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEHHHHCCCCCCCCCHHHHHHCCCCEEE
IDDFGTGYSSLSYLQNLDVDVLKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETT
EECCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RQEQWLRQHGVHYGQGWLYSKPLPATAFILWAEQRL
HHHHHHHHCCCCCCCCEEECCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]