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The map label for this gene is pgtP [H]

Identifier: 194734073

GI number: 194734073

Start: 2514836

End: 2516227

Strand: Direct

Name: pgtP [H]

Synonym: SeSA_A2629

Alternate gene names: 194734073

Gene position: 2514836-2516227 (Clockwise)

Preceding gene: 194737910

Following gene: 194737160

Centisome position: 53.4

GC content: 49.71

Gene sequence:

>1392_bases
ATGTTAACAATATTAAAAACAGGGCAATCGGCGCATAAAGTCCCACCGGAAAAAGTCCAGGCTACGTATGGTCGATATCG
TATACAGGCATTGTTAAGCGTATTTCTGGGATATCTCGCTTACTATATAGTCAGAAACAACTTCACATTATCGACGCCTT
ATTTAAAAGAGCAATTGGATCTCAGCGCTACGCAAATCGGCCTGCTGAGTAGCTGTATGCTTATTGCTTACGGAATCAGT
AAAGGCGTAATGAGCAGTCTGGCGGATAAAGCCAGTCCAAAAGTCTTCATGGCGTGCGGTCTGGTACTCTGCGCGATTGT
TAACGTTGGGCTGGGATTCAGTAGCGCATTCTGGATATTTGCCGCTCTGGTGGTCTTCAATGGCCTTTTTCAGGGCATGG
GCGTCGGCCCCTCGTTTATTACTATTGCAAACTGGTTCCCTCGTCGGGAGCGCGGACGCGTAGGCGCCTTCTGGAATATC
TCGCATAACGTTGGCGGCGGGATCGTCGCGCCTATCGTCGGTGCGGCTTTTGCGATATTGGGCAGCGAACACTGGCAAAG
CGCCAGTTATATCGTTCCGGCCTGCGTCGCCGTCATTTTTGCCTTAATTGTTCTGGTATTGGGAAAAGGTTCGCCGCGCG
AAGAAGGTCTTCCCTCCCTGGAACAGATGATGCCGGAAGAAAAAGTCATACTGAAAACGAAGAATACGGCAAAAGCGCCG
GAAAATATGAGCGCATGGCAAATCTTCTGTACTTATGTGCTGCGCAATAAAAATGCCTGGTATATTTCGCTGGTCGATGT
CTTCGTCTATATGGTGCGGTTTGGCATGATTAGCTGGTTGCCTATCTATCTGTTGACAGTAAAACACTTTTCAAAAGAAC
AGATGAGCGTCGCGTTTCTCTTTTTCGAGTGGGCGGCGATTCCTTCCACGCTACTGGCAGGCTGGCTGTCAGATAAACTG
TTTAAGGGCCGCAGAATGCCGTTAGCCATGATTTGCATGGCGCTGATTTTTGTCTGTCTGATCGGATACTGGAAAAGTGA
ATCTTTGCTGATGGTAACGATTTTCGCCGCCATTGTAGGTTGTCTGATTTACGTCCCGCAATTCCTCGCGTCCGTACAGA
CAATGGAGATAGTCCCCAGCTTTGCCGTAGGTTCCGCCGTCGGATTACGTGGGTTCATGAGCTATATTTTCGGCGCCTCG
TTGGGCACCAGCCTGTTTGGCGTCATGGTGGATAAACTGGGCTGGTACGGCGGATTTTATCTTCTGATGGGCGGTATCGT
ATGCTGCATTCTATTCTGTTACCTCTCCCATCGCGGCGCGCTGGAACTGGAACGTCAGCGCCAGAATGCGTTACATAATC
AGGACTCGCTGCAGCTTGCGGACGCGCAATAA

Upstream 100 bases:

>100_bases
ATTTTGACACATTTCTTCGACTTGAATTTTATTGTCACTCCTTTCACTCTACCGACAAAACCTCCTGATGTTCATCTCAC
TATAAAATACAGGTGACTCC

Downstream 100 bases:

>100_bases
ACGATTAGCCTTCCCGGGGAACAGAAGCGCCGACATCGTATATACCCAAAATAATTCGAGTTGCTTAAAGGCGGCAAGGG
AGTGAGTCCCCAGGAGCATA

Product: phosphoglycerate transport: transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MLTILKTGQSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGIS
KGVMSSLADKASPKVFMACGLVLCAIVNVGLGFSSAFWIFAALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNI
SHNVGGGIVAPIVGAAFAILGSEHWQSASYIVPACVAVIFALIVLVLGKGSPREEGLPSLEQMMPEEKVILKTKNTAKAP
ENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKL
FKGRRMPLAMICMALIFVCLIGYWKSESLLMVTIFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGAS
LGTSLFGVMVDKLGWYGGFYLLMGGIVCCILFCYLSHRGALELERQRQNALHNQDSLQLADAQ

Sequences:

>Translated_463_residues
MLTILKTGQSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGIS
KGVMSSLADKASPKVFMACGLVLCAIVNVGLGFSSAFWIFAALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNI
SHNVGGGIVAPIVGAAFAILGSEHWQSASYIVPACVAVIFALIVLVLGKGSPREEGLPSLEQMMPEEKVILKTKNTAKAP
ENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKL
FKGRRMPLAMICMALIFVCLIGYWKSESLLMVTIFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGAS
LGTSLFGVMVDKLGWYGGFYLLMGGIVCCILFCYLSHRGALELERQRQNALHNQDSLQLADAQ
>Mature_463_residues
MLTILKTGQSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGIS
KGVMSSLADKASPKVFMACGLVLCAIVNVGLGFSSAFWIFAALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNI
SHNVGGGIVAPIVGAAFAILGSEHWQSASYIVPACVAVIFALIVLVLGKGSPREEGLPSLEQMMPEEKVILKTKNTAKAP
ENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKL
FKGRRMPLAMICMALIFVCLIGYWKSESLLMVTIFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGAS
LGTSLFGVMVDKLGWYGGFYLLMGGIVCCILFCYLSHRGALELERQRQNALHNQDSLQLADAQ

Specific function: The phosphoglycerate transporter protein is a part of the PGT transport system. It is the membrane bound transporter for phosphoglycerate into salmonella [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=412, Percent_Identity=26.4563106796117, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4503847, Length=412, Percent_Identity=26.4563106796117, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI256219483, Length=412, Percent_Identity=26.4563106796117, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI256219543, Length=434, Percent_Identity=25.5760368663594, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI38093649, Length=406, Percent_Identity=24.384236453202, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI223717983, Length=406, Percent_Identity=24.384236453202, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI256219564, Length=343, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1788573, Length=462, Percent_Identity=36.3636363636364, Blast_Score=297, Evalue=9e-82,
Organism=Escherichia coli, GI2367259, Length=457, Percent_Identity=32.8227571115974, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87082310, Length=448, Percent_Identity=30.5803571428571, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI2367379, Length=328, Percent_Identity=25.3048780487805, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI2367193, Length=448, Percent_Identity=22.3214285714286, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082320, Length=398, Percent_Identity=22.3618090452261, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564202, Length=403, Percent_Identity=22.3325062034739, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564204, Length=403, Percent_Identity=22.3325062034739, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17542316, Length=445, Percent_Identity=20.8988764044944, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI133901856, Length=443, Percent_Identity=22.5733634311512, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI133901854, Length=443, Percent_Identity=22.5733634311512, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24656861, Length=486, Percent_Identity=21.6049382716049, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24656866, Length=486, Percent_Identity=21.6049382716049, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI45550478, Length=486, Percent_Identity=21.6049382716049, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51014; Mature: 51014

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTILKTGQSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLD
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHC
LSATQIGLLSSCMLIAYGISKGVMSSLADKASPKVFMACGLVLCAIVNVGLGFSSAFWIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
AALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNISHNVGGGIVAPIVGAAFAIL
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
GSEHWQSASYIVPACVAVIFALIVLVLGKGSPREEGLPSLEQMMPEEKVILKTKNTAKAP
CCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCC
ENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFL
CCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
FFEWAAIPSTLLAGWLSDKLFKGRRMPLAMICMALIFVCLIGYWKSESLLMVTIFAAIVG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
CLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGASLGTSLFGVMVDKLGWYGGFY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMGGIVCCILFCYLSHRGALELERQRQNALHNQDSLQLADAQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEECCCC
>Mature Secondary Structure
MLTILKTGQSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLD
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHC
LSATQIGLLSSCMLIAYGISKGVMSSLADKASPKVFMACGLVLCAIVNVGLGFSSAFWIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
AALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNISHNVGGGIVAPIVGAAFAIL
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
GSEHWQSASYIVPACVAVIFALIVLVLGKGSPREEGLPSLEQMMPEEKVILKTKNTAKAP
CCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCC
ENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFL
CCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
FFEWAAIPSTLLAGWLSDKLFKGRRMPLAMICMALIFVCLIGYWKSESLLMVTIFAAIVG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
CLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGASLGTSLFGVMVDKLGWYGGFY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMGGIVCCILFCYLSHRGALELERQRQNALHNQDSLQLADAQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 3042749 [H]