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The map label for this gene is purP [H]

Identifier: 194734042

GI number: 194734042

Start: 3933744

End: 3935081

Strand: Reverse

Name: purP [H]

Synonym: SeSA_A4060

Alternate gene names: 194734042

Gene position: 3935081-3933744 (Counterclockwise)

Preceding gene: 194736919

Following gene: 194736495

Centisome position: 83.56

GC content: 56.28

Gene sequence:

>1338_bases
ATGAGTCAACAACACACCACCCAGGCTTCTGGTCAGGGTATGCTGGAACGCGTGTTTAAACTGCGCGAACATGGCACGAC
GGCACGAACCGAAGTGATCGCCGGTTTTACCACTTTCCTGACGATGGTTTATATCGTTTTTGTTAACCCGCAAATTCTGG
GCGTAGCTGGCATGGACACCAGCGCCGTCTTTGTGACCACCTGTCTGATTGCAGCCTTTGGCAGCATTCTGATGGGCCTG
TTCGCTAACCTGCCGGTGGCGCTGGCGCCCGCGATGGGGCTGAATGCGTTCTTTGCCTTCGTGGTTGTTCAGGCAATGGG
ACTGCCGTGGCAGGTAGGCATGGGCGCCATTTTCTGGGGCGCTGTTGGTCTTTTATTGCTGACTATCTTCCGCGTGCGTT
ACTGGATGATCGCCAACATTCCGGTCAGCCTGCGCGTGGGCATCACCAGCGGCATCGGCCTGTTTATTGGCATGATGGGG
CTGAAAAACGCCGGCGTGATTGTCGCAAATCCGGAAACGCTGGTCAGCATCGGCAACCTGACCTCGCACAGCGTGCTGCT
GGGGGTTCTCGGATTCTTTATTATTGCGATTCTCGCTTCGCGCAACATTCATGCGGCGGTGCTGGTGTCCATCATCGTCA
CGACGCTGCTTGGCTGGATGATGGGCGATGTACACTACAACGGCATTGTCTCCGCGCCGCCAAGCGTCACCAGCGTGGTA
GGGCATGTCGATTTGGCAGGCTCGTTCAATCTTGGCCTGGCGGGGGTTATTTTCTCCTTCATGCTGGTAAACCTGTTTGA
CTCCTCCGGTACGCTGATTGGCGTGACCGATAAAGCCGGCCTGGCGGATGAGAAAGGCAAATTCCCGCGCATGAAGCAGG
CACTGTTTGTTGATAGTATCTCTTCCGTCACTGGCGCATTTGTCGGAACGTCTTCTGTGACCGCTTATATTGAATCGTCT
TCCGGCGTTTCGGTGGGCGGTCGCACCGGTTTGACGGCGGTGGTGGTCGGTATTTTGTTCCTGCTGGTTATCTTCCTGTC
GCCGCTGGCGGGCATGGTGCCGCCTTACGCGGCGGCGGGCGCGCTGATTTACGTCGGCGTGCTGATGACCTCCAGCCTGG
CGCGGGTAAACTGGCAGGATTTAACCGAATCGGTCCCGGCGTTTATTACGGCGGTAATGATGCCGTTTAGCTTCTCGATC
ACCGAAGGTATCGCGCTGGGCTTTATCTCTTACTGCGTGATGAAAATCGGGACAGGCCGCCTACGCGACCTTAGCCCGTG
CGTAGTGATTGTCGCGCTGTTATTCGTGCTGAAGATTGTGTTTATTGACGCACACTGA

Upstream 100 bases:

>100_bases
TAACAAATTGAGTGAAAAAAATTACCACACAACTGCGCCAGGTGTCGCATTTTGGTATAGGATAACGGCGAATTTTCCCT
CCTTTCTCCGGAAATTGATA

Downstream 100 bases:

>100_bases
TGAAATGAACCCTCGCCCCATCGGGGGAGGGTTTTTAAATAACTTACGCTTTAACGCGCTGAATAAACTCGCCAAATGCG
GTCAGCTGACCGGTCAAATG

Product: inner membrane protein YicO

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSILMGL
FANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWGAVGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
LKNAGVIVANPETLVSIGNLTSHSVLLGVLGFFIIAILASRNIHAAVLVSIIVTTLLGWMMGDVHYNGIVSAPPSVTSVV
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADEKGKFPRMKQALFVDSISSVTGAFVGTSSVTAYIESS
SGVSVGGRTGLTAVVVGILFLLVIFLSPLAGMVPPYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSI
TEGIALGFISYCVMKIGTGRLRDLSPCVVIVALLFVLKIVFIDAH

Sequences:

>Translated_445_residues
MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSILMGL
FANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWGAVGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
LKNAGVIVANPETLVSIGNLTSHSVLLGVLGFFIIAILASRNIHAAVLVSIIVTTLLGWMMGDVHYNGIVSAPPSVTSVV
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADEKGKFPRMKQALFVDSISSVTGAFVGTSSVTAYIESS
SGVSVGGRTGLTAVVVGILFLLVIFLSPLAGMVPPYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSI
TEGIALGFISYCVMKIGTGRLRDLSPCVVIVALLFVLKIVFIDAH
>Mature_444_residues
SQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSILMGLF
ANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWGAVGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMGL
KNAGVIVANPETLVSIGNLTSHSVLLGVLGFFIIAILASRNIHAAVLVSIIVTTLLGWMMGDVHYNGIVSAPPSVTSVVG
HVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADEKGKFPRMKQALFVDSISSVTGAFVGTSSVTAYIESSS
GVSVGGRTGLTAVVVGILFLLVIFLSPLAGMVPPYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSIT
EGIALGFISYCVMKIGTGRLRDLSPCVVIVALLFVLKIVFIDAH

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=445, Percent_Identity=96.4044943820225, Blast_Score=835, Evalue=0.0,
Organism=Escherichia coli, GI87082309, Length=444, Percent_Identity=74.0990990990991, Blast_Score=666, Evalue=0.0,
Organism=Escherichia coli, GI1790499, Length=439, Percent_Identity=36.6742596810934, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI48994909, Length=436, Percent_Identity=37.3853211009174, Blast_Score=256, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46735; Mature: 46604

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDT
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
SAVFVTTCLIAAFGSILMGLFANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AVGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMGLKNAGVIVANPETLVSIGNL
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCHHHEEECCC
TSHSVLLGVLGFFIIAILASRNIHAAVLVSIIVTTLLGWMMGDVHYNGIVSAPPSVTSVV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHH
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADEKGKFPRMKQALFVDSI
HHHEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHH
SSVTGAFVGTSSVTAYIESSSGVSVGGRTGLTAVVVGILFLLVIFLSPLAGMVPPYAAAG
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSITEGIALGFISYCVMKIGTGR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
LRDLSPCVVIVALLFVLKIVFIDAH
CCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDT
CCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
SAVFVTTCLIAAFGSILMGLFANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AVGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMGLKNAGVIVANPETLVSIGNL
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCHHHEEECCC
TSHSVLLGVLGFFIIAILASRNIHAAVLVSIIVTTLLGWMMGDVHYNGIVSAPPSVTSVV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHH
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADEKGKFPRMKQALFVDSI
HHHEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHH
SSVTGAFVGTSSVTAYIESSSGVSVGGRTGLTAVVVGILFLLVIFLSPLAGMVPPYAAAG
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSITEGIALGFISYCVMKIGTGR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
LRDLSPCVVIVALLFVLKIVFIDAH
CCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]