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The map label for this gene is oxaA

Identifier: 194335113

GI number: 194335113

Start: 2509732

End: 2511486

Strand: Reverse

Name: oxaA

Synonym: Paes_2335

Alternate gene names: 194335113

Gene position: 2511486-2509732 (Counterclockwise)

Preceding gene: 194335114

Following gene: 194335112

Centisome position: 99.94

GC content: 48.66

Gene sequence:

>1755_bases
ATGGATAGAAATTCAGTGATCGGACTTGTCTTGATCTCGTTGATCATGATCGTGTGGATGCAGTTCATGGCCCCTGAGAA
AAAGCCCCTTCAGGATATAGATAAGCCGGCAGTCTCTCTTCAGGAAGAGGTCTCTCCGGTGAGCGATATTCCTGCTGCCG
CTGCCACGCCTGAATCATATGGTGAATTTTCTGCCATGTCTGACGGGGAAGAGAAGCTCCTGACCGTTGATAACGAGTAT
TTCACGGCGGTGCTTTCCAGCCGGGGTGCTACACTGAAGTCCATGATGTTGAAAAAACATCTTGATTCTTCTCGTGAGCA
GTTCAATCTTATTCGTAAGAATGACAGTGGTGCACTCTCTTTGTTTTTTCTGACGCAGGCAGGCAAACAGATCGATACCC
GTGATCTCTATTTTTCTACAGCGGTTACTGAGAGTCAGGTCACGGTCGGTGCCGATAACCAGTTTAGCGTTACCTACCGC
CTGGATGTTGCTCCCGAAAAAAATATTGTTATCACCTATACGTTTTCAGGTGACAGTTATGCCATCGGCTACGATATCAG
CATGAACGGCTTTGCCTCTGAGATTGCAGGCAATGAGTTTCAGCTCCAGTGGGATGGAGGCCTTGTTCATTCCGAGAAAA
ACGATGATGACGAACTGCACAACTCCTGGGCGGCTGCATATATGGGCGGCAGTCTCCTGAAGCTTGACGCTTCAGACCAG
TCTAAAACCTACCGTGAGGAGCAGTCAGGTGTTGCCGGATGGGTTGCTGCAAGAACGAAATATTTCGTCGCTGCCATGAT
CCCGTCGTCAGAGACCGAGGGAGTGTACCTTGCAGGAAAGCGTCTTGCAGGTGAGCCATTTGAAAATTATACGACCGCGT
TGAAGTTCAGGGTGCCTTCTGATGAGTCCTCCTTTAAGGAGTCGCTCCGTCTCTATGTCGGTCCGATTGATTATAACGTC
TTGAACGCTCTCGGCGTCAACCTTGAAAAGATCATGGATTTTGGTTGGGACTGGCTGACGCGTCCATTCGCCGAATATAT
TATTCTGCCGATTTTCGATCTTCTCAACAAGTTTATCGGCAACTATGGTCTGATTATCATTATTTTCGCATTTCTCATCA
AGCTGGTGACCTATCCGCTGACCATGGCTTCAACGAAGTCGATGAAGAAGATGTCAGCTCTTCAGCCAATGATGAAGGAG
ATCCAGGAGAAGTATAAAGATAATCCCGCCAAGCTGCAGAGCGAGCTTGGAAGGATCTACAAAGAGGCCGGGGTTAATCC
GCTTGGCGGATGTCTTCCGGTCGTGCTTCAGATGCCCCTGCTTTTTGCGATGTTCTATGTTTTCCGTTCCTCCATTCAGC
TGCGTCAGCACGGATTTCTCTGGGCAAATGATCTTTCCGTGCCGGACTCTATCCTTGATTTTGGCTTCAGTATCCCGCTC
TACGGTGACCATATTGCACTGTTCCCGATCCTGATGGCCGTCGCAGTCTTCCTGCAGCAGAAGATTACCCCTACAGCACA
GACCAACGATCAGATGAAGGCCATGATCTATATTTTCCCGGTCATGATGCTGTTGTTTTTCAATAACATGCCGGCAGGAC
TCGGATTGTACTATCTGATGTTCAACGTCTTCAGTATAGCGCAGACCTGGTATATCAACAAGACTGCATCTACCGATGAT
CTTCCTGCGCTTTCGCCGGTTGTCGCAGCTCCGCCAAAAGCTCCGAAAAAGAAAAAGAACGCCAGAAAGCGTTAA

Upstream 100 bases:

>100_bases
CTGACCGTCTGGCGGGTTCTCCGATGCAATCCTTTTTCCAGAGGGGGGTATGATCCCGTCCCTTTGCCCGGCAATACATC
AAATTCTAAAAAAAGAGATA

Downstream 100 bases:

>100_bases
GAAAGGTACCATATGGAATGGTTGCAGCAGGTCGATACCTGGCTGTTTCAGCTCCTGAACCTGCATCTGGTTCATCCGGC
AGCTGATGATCTCATGGTGT

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MDRNSVIGLVLISLIMIVWMQFMAPEKKPLQDIDKPAVSLQEEVSPVSDIPAAAATPESYGEFSAMSDGEEKLLTVDNEY
FTAVLSSRGATLKSMMLKKHLDSSREQFNLIRKNDSGALSLFFLTQAGKQIDTRDLYFSTAVTESQVTVGADNQFSVTYR
LDVAPEKNIVITYTFSGDSYAIGYDISMNGFASEIAGNEFQLQWDGGLVHSEKNDDDELHNSWAAAYMGGSLLKLDASDQ
SKTYREEQSGVAGWVAARTKYFVAAMIPSSETEGVYLAGKRLAGEPFENYTTALKFRVPSDESSFKESLRLYVGPIDYNV
LNALGVNLEKIMDFGWDWLTRPFAEYIILPIFDLLNKFIGNYGLIIIIFAFLIKLVTYPLTMASTKSMKKMSALQPMMKE
IQEKYKDNPAKLQSELGRIYKEAGVNPLGGCLPVVLQMPLLFAMFYVFRSSIQLRQHGFLWANDLSVPDSILDFGFSIPL
YGDHIALFPILMAVAVFLQQKITPTAQTNDQMKAMIYIFPVMMLLFFNNMPAGLGLYYLMFNVFSIAQTWYINKTASTDD
LPALSPVVAAPPKAPKKKKNARKR

Sequences:

>Translated_584_residues
MDRNSVIGLVLISLIMIVWMQFMAPEKKPLQDIDKPAVSLQEEVSPVSDIPAAAATPESYGEFSAMSDGEEKLLTVDNEY
FTAVLSSRGATLKSMMLKKHLDSSREQFNLIRKNDSGALSLFFLTQAGKQIDTRDLYFSTAVTESQVTVGADNQFSVTYR
LDVAPEKNIVITYTFSGDSYAIGYDISMNGFASEIAGNEFQLQWDGGLVHSEKNDDDELHNSWAAAYMGGSLLKLDASDQ
SKTYREEQSGVAGWVAARTKYFVAAMIPSSETEGVYLAGKRLAGEPFENYTTALKFRVPSDESSFKESLRLYVGPIDYNV
LNALGVNLEKIMDFGWDWLTRPFAEYIILPIFDLLNKFIGNYGLIIIIFAFLIKLVTYPLTMASTKSMKKMSALQPMMKE
IQEKYKDNPAKLQSELGRIYKEAGVNPLGGCLPVVLQMPLLFAMFYVFRSSIQLRQHGFLWANDLSVPDSILDFGFSIPL
YGDHIALFPILMAVAVFLQQKITPTAQTNDQMKAMIYIFPVMMLLFFNNMPAGLGLYYLMFNVFSIAQTWYINKTASTDD
LPALSPVVAAPPKAPKKKKNARKR
>Mature_584_residues
MDRNSVIGLVLISLIMIVWMQFMAPEKKPLQDIDKPAVSLQEEVSPVSDIPAAAATPESYGEFSAMSDGEEKLLTVDNEY
FTAVLSSRGATLKSMMLKKHLDSSREQFNLIRKNDSGALSLFFLTQAGKQIDTRDLYFSTAVTESQVTVGADNQFSVTYR
LDVAPEKNIVITYTFSGDSYAIGYDISMNGFASEIAGNEFQLQWDGGLVHSEKNDDDELHNSWAAAYMGGSLLKLDASDQ
SKTYREEQSGVAGWVAARTKYFVAAMIPSSETEGVYLAGKRLAGEPFENYTTALKFRVPSDESSFKESLRLYVGPIDYNV
LNALGVNLEKIMDFGWDWLTRPFAEYIILPIFDLLNKFIGNYGLIIIIFAFLIKLVTYPLTMASTKSMKKMSALQPMMKE
IQEKYKDNPAKLQSELGRIYKEAGVNPLGGCLPVVLQMPLLFAMFYVFRSSIQLRQHGFLWANDLSVPDSILDFGFSIPL
YGDHIALFPILMAVAVFLQQKITPTAQTNDQMKAMIYIFPVMMLLFFNNMPAGLGLYYLMFNVFSIAQTWYINKTASTDD
LPALSPVVAAPPKAPKKKKNARKR

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=304, Percent_Identity=33.8815789473684, Blast_Score=179, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_PROA2 (B4S6X1)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002016973.1
- GeneID:   6459398
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_2335
- HOGENOM:   HBG405598
- OMA:   YVFRSSI
- ProtClustDB:   CLSK637099
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 65286; Mature: 65286

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1ef1621c)-; HASH(0x1f99887c)-; HASH(0x1f245250)-; HASH(0x1f9b7c90)-; HASH(0x1f998918)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRNSVIGLVLISLIMIVWMQFMAPEKKPLQDIDKPAVSLQEEVSPVSDIPAAAATPESY
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHHHHHHHCCCHHCCCCCCCCCHHH
GEFSAMSDGEEKLLTVDNEYFTAVLSSRGATLKSMMLKKHLDSSREQFNLIRKNDSGALS
CCCCCCCCCCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHEECCCCCEE
LFFLTQAGKQIDTRDLYFSTAVTESQVTVGADNQFSVTYRLDVAPEKNIVITYTFSGDSY
EEEEECCCCCCCCHHEEEEEEECCCEEEECCCCEEEEEEEEECCCCCCEEEEEEECCCCE
AIGYDISMNGFASEIAGNEFQLQWDGGLVHSEKNDDDELHNSWAAAYMGGSLLKLDASDQ
EEEEEEECCCHHHHHCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCC
SKTYREEQSGVAGWVAARTKYFVAAMIPSSETEGVYLAGKRLAGEPFENYTTALKFRVPS
HHHHHHHHCCCHHHHHHHHHEEEEEECCCCCCCCEEEECCCCCCCCCCCCEEEEEEECCC
DESSFKESLRLYVGPIDYNVLNALGVNLEKIMDFGWDWLTRPFAEYIILPIFDLLNKFIG
CHHHHHHHHEEEECCCCHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
NYGLIIIIFAFLIKLVTYPLTMASTKSMKKMSALQPMMKEIQEKYKDNPAKLQSELGRIY
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KEAGVNPLGGCLPVVLQMPLLFAMFYVFRSSIQLRQHGFLWANDLSVPDSILDFGFSIPL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHCCCCCCC
YGDHIALFPILMAVAVFLQQKITPTAQTNDQMKAMIYIFPVMMLLFFNNMPAGLGLYYLM
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FNVFSIAQTWYINKTASTDDLPALSPVVAAPPKAPKKKKNARKR
HHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCH
>Mature Secondary Structure
MDRNSVIGLVLISLIMIVWMQFMAPEKKPLQDIDKPAVSLQEEVSPVSDIPAAAATPESY
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHHHHHHHCCCHHCCCCCCCCCHHH
GEFSAMSDGEEKLLTVDNEYFTAVLSSRGATLKSMMLKKHLDSSREQFNLIRKNDSGALS
CCCCCCCCCCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHEECCCCCEE
LFFLTQAGKQIDTRDLYFSTAVTESQVTVGADNQFSVTYRLDVAPEKNIVITYTFSGDSY
EEEEECCCCCCCCHHEEEEEEECCCEEEECCCCEEEEEEEEECCCCCCEEEEEEECCCCE
AIGYDISMNGFASEIAGNEFQLQWDGGLVHSEKNDDDELHNSWAAAYMGGSLLKLDASDQ
EEEEEEECCCHHHHHCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCC
SKTYREEQSGVAGWVAARTKYFVAAMIPSSETEGVYLAGKRLAGEPFENYTTALKFRVPS
HHHHHHHHCCCHHHHHHHHHEEEEEECCCCCCCCEEEECCCCCCCCCCCCEEEEEEECCC
DESSFKESLRLYVGPIDYNVLNALGVNLEKIMDFGWDWLTRPFAEYIILPIFDLLNKFIG
CHHHHHHHHEEEECCCCHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
NYGLIIIIFAFLIKLVTYPLTMASTKSMKKMSALQPMMKEIQEKYKDNPAKLQSELGRIY
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KEAGVNPLGGCLPVVLQMPLLFAMFYVFRSSIQLRQHGFLWANDLSVPDSILDFGFSIPL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHCCCCCCC
YGDHIALFPILMAVAVFLQQKITPTAQTNDQMKAMIYIFPVMMLLFFNNMPAGLGLYYLM
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FNVFSIAQTWYINKTASTDDLPALSPVVAAPPKAPKKKKNARKR
HHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA