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The map label for this gene is murB1 [H]

Identifier: 194335105

GI number: 194335105

Start: 2502245

End: 2503207

Strand: Reverse

Name: murB1 [H]

Synonym: Paes_2327

Alternate gene names: 194335105

Gene position: 2503207-2502245 (Counterclockwise)

Preceding gene: 194335107

Following gene: 194335104

Centisome position: 99.61

GC content: 55.56

Gene sequence:

>963_bases
ATGGATTGCATAAGCGAAAATGACATGGATATGCTCCGTGACATCTGTTCTGGAGATGTGTTGCAGGGCGTTGATCTTTC
TGATATAAGCCATTGGCGGATCGGGGGCCGCGCGGCGCTTGTATTGCGTCCGTCATCGACAACCGAAGTTGCTGCATTGC
GCCGCTGGTTTTACCAGCGTGGGATGGCGCATCTGGTCATAGGTAAGACGACCAATGTGCTTTTTGCCGACGAGGGATTG
CACGTGCCCTGTATTCAAATCGGAGCGGTAATGTCGAAGCTCAGCATCGAGCACGGTGAGGTGTATGCCGATGCGGGTGT
CTGGGTGCCCGGCCTGTCGCGCACATTGATGCTGAACGGTTTGACCGGCGGTGAGCACCTGTGCGGCATTCCCGGCACAC
TTGGCGGATTGATCTGCATGAACGGGGGGAGCAACAGCCGCTCGATCGGCGGCAATGTGATCAGTGTGGAAAGTGTCGAC
AGCCGTGGATCAATTGTCGAGCGCGACGCCAAAGAGTGCGGATTTGGTTATCGCAGCTCCATCTACCAGACGAATGATGA
GATCGTCACTGCTGTACGCATGCGATTCCTGCCGGGTGTCTGTTCGGCAATCCGGGTTGAAATGCTGAAGGACCTGGCGA
ATCGCAGGAGAAAATTTCCTCTCAAGGAGCCGAGTTGCGGATCTGTTTTTAAAAGCAGTCCAGGCATATACGCCGACTTC
GGACCTCCCGGAGCCGTTATCGAAAGACTGGGATTCAAGGGAATGCGTGTCGGCGGGGCGATGGTATCGCCCAAACATGC
AAATTTTATCGTCAACACCGGCCGGGCGAAAGCGGCGGACGTTCTGGAAATCATGAAAAGCATTCGTGACGCGGTATACG
CCCAAACAGGATACCTGCTGGAGGCCGAAGCCCGTTACGTGACTCCGGGAGGAAAGGTCCTGCCTGCAAGTAGCGTTCTC
TGA

Upstream 100 bases:

>100_bases
TCTCTAACGGCGGGCGGGAACTCAAATCACTACTCTTTCTTTACTATCTTTCTTCCGGTAGCCATTATGCGCTATACGAT
AACTGAACATTCTGTGCGGG

Downstream 100 bases:

>100_bases
GAGGATGTCGTGGATCCTTCTTATATGCCATTGATCGTATTTCAGCGGGGATTGCGAATACCCTGCTGATCTGGAGTCTG
GATCGCCTCTGCTGACCCAG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase 1 [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MDCISENDMDMLRDICSGDVLQGVDLSDISHWRIGGRAALVLRPSSTTEVAALRRWFYQRGMAHLVIGKTTNVLFADEGL
HVPCIQIGAVMSKLSIEHGEVYADAGVWVPGLSRTLMLNGLTGGEHLCGIPGTLGGLICMNGGSNSRSIGGNVISVESVD
SRGSIVERDAKECGFGYRSSIYQTNDEIVTAVRMRFLPGVCSAIRVEMLKDLANRRRKFPLKEPSCGSVFKSSPGIYADF
GPPGAVIERLGFKGMRVGGAMVSPKHANFIVNTGRAKAADVLEIMKSIRDAVYAQTGYLLEAEARYVTPGGKVLPASSVL

Sequences:

>Translated_320_residues
MDCISENDMDMLRDICSGDVLQGVDLSDISHWRIGGRAALVLRPSSTTEVAALRRWFYQRGMAHLVIGKTTNVLFADEGL
HVPCIQIGAVMSKLSIEHGEVYADAGVWVPGLSRTLMLNGLTGGEHLCGIPGTLGGLICMNGGSNSRSIGGNVISVESVD
SRGSIVERDAKECGFGYRSSIYQTNDEIVTAVRMRFLPGVCSAIRVEMLKDLANRRRKFPLKEPSCGSVFKSSPGIYADF
GPPGAVIERLGFKGMRVGGAMVSPKHANFIVNTGRAKAADVLEIMKSIRDAVYAQTGYLLEAEARYVTPGGKVLPASSVL
>Mature_320_residues
MDCISENDMDMLRDICSGDVLQGVDLSDISHWRIGGRAALVLRPSSTTEVAALRRWFYQRGMAHLVIGKTTNVLFADEGL
HVPCIQIGAVMSKLSIEHGEVYADAGVWVPGLSRTLMLNGLTGGEHLCGIPGTLGGLICMNGGSNSRSIGGNVISVESVD
SRGSIVERDAKECGFGYRSSIYQTNDEIVTAVRMRFLPGVCSAIRVEMLKDLANRRRKFPLKEPSCGSVFKSSPGIYADF
GPPGAVIERLGFKGMRVGGAMVSPKHANFIVNTGRAKAADVLEIMKSIRDAVYAQTGYLLEAEARYVTPGGKVLPASSVL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 34327; Mature: 34327

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDCISENDMDMLRDICSGDVLQGVDLSDISHWRIGGRAALVLRPSSTTEVAALRRWFYQR
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEECCEEEEEECCCCCHHHHHHHHHHHHC
GMAHLVIGKTTNVLFADEGLHVPCIQIGAVMSKLSIEHGEVYADAGVWVPGLSRTLMLNG
CCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEEEC
LTGGEHLCGIPGTLGGLICMNGGSNSRSIGGNVISVESVDSRGSIVERDAKECGFGYRSS
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHH
IYQTNDEIVTAVRMRFLPGVCSAIRVEMLKDLANRRRKFPLKEPSCGSVFKSSPGIYADF
HEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCEEECC
GPPGAVIERLGFKGMRVGGAMVSPKHANFIVNTGRAKAADVLEIMKSIRDAVYAQTGYLL
CCCHHHHHHHCCCCEEECCEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEE
EAEARYVTPGGKVLPASSVL
ECCCEEECCCCCCCCHHCCC
>Mature Secondary Structure
MDCISENDMDMLRDICSGDVLQGVDLSDISHWRIGGRAALVLRPSSTTEVAALRRWFYQR
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEECCEEEEEECCCCCHHHHHHHHHHHHC
GMAHLVIGKTTNVLFADEGLHVPCIQIGAVMSKLSIEHGEVYADAGVWVPGLSRTLMLNG
CCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEEEC
LTGGEHLCGIPGTLGGLICMNGGSNSRSIGGNVISVESVDSRGSIVERDAKECGFGYRSS
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHH
IYQTNDEIVTAVRMRFLPGVCSAIRVEMLKDLANRRRKFPLKEPSCGSVFKSSPGIYADF
HEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCEEECC
GPPGAVIERLGFKGMRVGGAMVSPKHANFIVNTGRAKAADVLEIMKSIRDAVYAQTGYLL
CCCHHHHHHHCCCCEEECCEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEE
EAEARYVTPGGKVLPASSVL
ECCCEEECCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]