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The map label for this gene is cat2 [H]

Identifier: 194335042

GI number: 194335042

Start: 2430778

End: 2432064

Strand: Reverse

Name: cat2 [H]

Synonym: Paes_2254

Alternate gene names: 194335042

Gene position: 2432064-2430778 (Counterclockwise)

Preceding gene: 194335043

Following gene: 194335040

Centisome position: 96.78

GC content: 52.37

Gene sequence:

>1287_bases
ATGAAATACCGGACAATGTCTGCCGATGAAGCGGTTTCGGCTGTTCAGTCTGGAGACAGGATTTTTCTTCATACGGCGGC
GGCGACGCCCAAGCGGCTTATCGACGCGCTTGTCAGGAGAGCCGGATCGTTGAGGGATGTTGAAATTGTCAGTCTGCATA
CGGAAGGGGAGGCTGACTATGTGAAGCCGGAGTATCGGGAGAGTTTCCGGCTCAACGCATTTTTTGTCGGCAGAAACGTA
CGGTGCGCCGTTCAGGAAGGTCTTGCTGACGCTATTCCGATTTTTCTCAGCGATGTCCCTGCGCTTTTTCACAATAATGT
TCTTCCTCTGGATGTCGCTTTTGTTCATGTTTCCCCTCCGGACCGCCACGGCTATTGTTCTCTCGGGGTATCGGTAGACG
CTGCTCTGGCGGCTGTACACAAGGCGAAATATGTCATTGCGCAGGTCAATCCCTTCATGCCGCGTACTCATGGCGAGGGG
CTTCTGCATCTCAGTCATATCGATGCGCTGGTGGATGTTGATGATCCGCTTCCTGAAATACCGAGGCATGAGCTGACCGA
TATTGAACGCAGAATCGGTGAAAATGTCGCTTCGATTGTTGAGGATGGCGCGACCCTCCAGATGGGGATCGGAGCGATTC
CTGACGCCACGCTTGCCGCGCTTTCAGGGCATCGCGATATCGGCGTGCATACTGAAATGTTTTCCGATGGTCTCGTCGAC
CTTGTTGAAAAAGGCGTGATTAACGGAAAGTACAAACGGACGCACAAGGAGATTATTGTGGCGAGCTTTCTTGTCGGTAC
GCGTAAACTCTATGATTTTGTCGATGACAATCCTCTTGTGGAGATGTTTCCATCCGACTATGTCAATGATACCAGGGAGA
TTCGTAAAAACCCCAAGGTTACAGCCATCAATAGTGCGATAGAAATAGATATGTCAGGTCAGGTTTGTGCTGATTCAATC
GGGCAGAAGCATTTTTCAGGTGTCGGTGGTCAGATGGATTTTATTCGAGGTGCGGCACTTTCTGAAGGAGGCAAGCCGAT
CATTGCGCTGCCATCGGTGACCAGAAAGGGTGCTTCGCGTATTGTTCCGATGCTTAAGCCTGGCGCGGGCGTTGTGACGA
CGAGAGCTCATGTTCAGTATGTCGTGACCGAGTATGGCATCGTCAACCTGCACGGGAGAAACATGCGGCAGCGGGCAGAG
GCGCTTGCAAGCATCGCTCACCCGGATTTCCGGGAAGGCATTCTTCGTGCTGCGTACGATCTGTACGGGGGAAAGGCGCG
CTGTTAA

Upstream 100 bases:

>100_bases
AGTACTGATCGTCAAACAGCGCATTGAGTGTTTGATGTTTGGTTTGATAGTTGATGTAATGAATTGTTAAGCGCGAAGCG
TGATATAAAGGAGTTTATTT

Downstream 100 bases:

>100_bases
GTGATTGACGCAAAAAAAATGCTCCGGAACTCCGGAGCATTTTTTTTGTGCTGTATCGTTTTGCCGGGAGGTTATGCCGG
TTTGACGGCTTCGACAAAGA

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MKYRTMSADEAVSAVQSGDRIFLHTAAATPKRLIDALVRRAGSLRDVEIVSLHTEGEADYVKPEYRESFRLNAFFVGRNV
RCAVQEGLADAIPIFLSDVPALFHNNVLPLDVAFVHVSPPDRHGYCSLGVSVDAALAAVHKAKYVIAQVNPFMPRTHGEG
LLHLSHIDALVDVDDPLPEIPRHELTDIERRIGENVASIVEDGATLQMGIGAIPDATLAALSGHRDIGVHTEMFSDGLVD
LVEKGVINGKYKRTHKEIIVASFLVGTRKLYDFVDDNPLVEMFPSDYVNDTREIRKNPKVTAINSAIEIDMSGQVCADSI
GQKHFSGVGGQMDFIRGAALSEGGKPIIALPSVTRKGASRIVPMLKPGAGVVTTRAHVQYVVTEYGIVNLHGRNMRQRAE
ALASIAHPDFREGILRAAYDLYGGKARC

Sequences:

>Translated_428_residues
MKYRTMSADEAVSAVQSGDRIFLHTAAATPKRLIDALVRRAGSLRDVEIVSLHTEGEADYVKPEYRESFRLNAFFVGRNV
RCAVQEGLADAIPIFLSDVPALFHNNVLPLDVAFVHVSPPDRHGYCSLGVSVDAALAAVHKAKYVIAQVNPFMPRTHGEG
LLHLSHIDALVDVDDPLPEIPRHELTDIERRIGENVASIVEDGATLQMGIGAIPDATLAALSGHRDIGVHTEMFSDGLVD
LVEKGVINGKYKRTHKEIIVASFLVGTRKLYDFVDDNPLVEMFPSDYVNDTREIRKNPKVTAINSAIEIDMSGQVCADSI
GQKHFSGVGGQMDFIRGAALSEGGKPIIALPSVTRKGASRIVPMLKPGAGVVTTRAHVQYVVTEYGIVNLHGRNMRQRAE
ALASIAHPDFREGILRAAYDLYGGKARC
>Mature_428_residues
MKYRTMSADEAVSAVQSGDRIFLHTAAATPKRLIDALVRRAGSLRDVEIVSLHTEGEADYVKPEYRESFRLNAFFVGRNV
RCAVQEGLADAIPIFLSDVPALFHNNVLPLDVAFVHVSPPDRHGYCSLGVSVDAALAAVHKAKYVIAQVNPFMPRTHGEG
LLHLSHIDALVDVDDPLPEIPRHELTDIERRIGENVASIVEDGATLQMGIGAIPDATLAALSGHRDIGVHTEMFSDGLVD
LVEKGVINGKYKRTHKEIIVASFLVGTRKLYDFVDDNPLVEMFPSDYVNDTREIRKNPKVTAINSAIEIDMSGQVCADSI
GQKHFSGVGGQMDFIRGAALSEGGKPIIALPSVTRKGASRIVPMLKPGAGVVTTRAHVQYVVTEYGIVNLHGRNMRQRAE
ALASIAHPDFREGILRAAYDLYGGKARC

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=484, Percent_Identity=24.5867768595041, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32563853, Length=424, Percent_Identity=50.4716981132076, Blast_Score=426, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17538151, Length=428, Percent_Identity=46.4953271028037, Blast_Score=382, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6319456, Length=221, Percent_Identity=28.9592760180996, Blast_Score=76, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21358615, Length=417, Percent_Identity=52.757793764988, Blast_Score=468, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 46599; Mature: 46599

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYRTMSADEAVSAVQSGDRIFLHTAAATPKRLIDALVRRAGSLRDVEIVSLHTEGEADY
CCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCC
VKPEYRESFRLNAFFVGRNVRCAVQEGLADAIPIFLSDVPALFHNNVLPLDVAFVHVSPP
CCCHHHHCEEEEEEEECCCCEEHHHHCCHHHHHHHHHCCHHHHCCCCCEEEEEEEEECCC
DRHGYCSLGVSVDAALAAVHKAKYVIAQVNPFMPRTHGEGLLHLSHIDALVDVDDPLPEI
CCCCEEEECCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEEEHHHHEEECCCCCCCC
PRHELTDIERRIGENVASIVEDGATLQMGIGAIPDATLAALSGHRDIGVHTEMFSDGLVD
CCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHH
LVEKGVINGKYKRTHKEIIVASFLVGTRKLYDFVDDNPLVEMFPSDYVNDTREIRKNPKV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHCHHHHHHCCCCE
TAINSAIEIDMSGQVCADSIGQKHFSGVGGQMDFIRGAALSEGGKPIIALPSVTRKGASR
EEECCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHCHHHCCCCCCEEECCCCHHHHHHH
IVPMLKPGAGVVTTRAHVQYVVTEYGIVNLHGRNMRQRAEALASIAHPDFREGILRAAYD
CCCCCCCCCCEEEEHHHHEEEEECCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
LYGGKARC
HCCCCCCC
>Mature Secondary Structure
MKYRTMSADEAVSAVQSGDRIFLHTAAATPKRLIDALVRRAGSLRDVEIVSLHTEGEADY
CCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCC
VKPEYRESFRLNAFFVGRNVRCAVQEGLADAIPIFLSDVPALFHNNVLPLDVAFVHVSPP
CCCHHHHCEEEEEEEECCCCEEHHHHCCHHHHHHHHHCCHHHHCCCCCEEEEEEEEECCC
DRHGYCSLGVSVDAALAAVHKAKYVIAQVNPFMPRTHGEGLLHLSHIDALVDVDDPLPEI
CCCCEEEECCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEEEHHHHEEECCCCCCCC
PRHELTDIERRIGENVASIVEDGATLQMGIGAIPDATLAALSGHRDIGVHTEMFSDGLVD
CCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHH
LVEKGVINGKYKRTHKEIIVASFLVGTRKLYDFVDDNPLVEMFPSDYVNDTREIRKNPKV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHCHHHHHHCCCCE
TAINSAIEIDMSGQVCADSIGQKHFSGVGGQMDFIRGAALSEGGKPIIALPSVTRKGASR
EEECCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHCHHHCCCCCCEEECCCCHHHHHHH
IVPMLKPGAGVVTTRAHVQYVVTEYGIVNLHGRNMRQRAEALASIAHPDFREGILRAAYD
CCCCCCCCCCEEEEHHHHEEEEECCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
LYGGKARC
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]