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The map label for this gene is nadD

Identifier: 194335028

GI number: 194335028

Start: 2420268

End: 2420879

Strand: Reverse

Name: nadD

Synonym: Paes_2239

Alternate gene names: 194335028

Gene position: 2420879-2420268 (Counterclockwise)

Preceding gene: 194335029

Following gene: 194335024

Centisome position: 96.34

GC content: 53.92

Gene sequence:

>612_bases
GTGCGACTTGCCCTCTTTGGCGGCTCTTTTGATCCGCCGCATAATGCTCATCTGGCGCTTTGCCTCTGCGCCAGAGAGTT
GCTTGATATCGATAAGCTGATTATTTCGGTTTCCAACAATCCCCTGAAAGAAAACAGGTCTGCCTCCAATGCTCATCGCC
TGGCAATGGCGGAGCTGCTCGTCTCGGAGATCAATGCTACCGGCAGGATTGCCGAGGTCTCTCGATGGGAACTCGAACGT
TCAGGGCCCTCCTATACCATCGACCTGCTGACCCGCATCGGGCAGCTCTATCCAGAAGAGCCGGTCACACTTCTGATCGG
AGAGGATAATTTCAGGGGCTTTCGGCAGTGGAAATCCTGGCAGGAGATTCTGGAGCGCTGTTATGTGGTTGTTTTTCGCA
GGCCATTGGAGCATGCCGCATTTGACGATGCCTACGCTCATTTGCCGGGCATTCCGGACAGGCATCAGGTTCGGTTTATT
GATTTTGATTTTCAGCTCTCCTCAACCGCAATCCGTTACGCTATAGCAACCGGGGAGCCCTACGCCCATCTGGTGCCACC
TTCGATAGCTGACTATATCGCTTCCCGACATCTCTACAGCGAACGCTCCTGA

Upstream 100 bases:

>100_bases
TGCATTAGAGGCCTATGACCGCCAGTTTCCTGAAAATATGGAGAATGTTGAGGATTACCGGAATAAGATCATGAAACATT
TCACAAACTCCTGATTGGCG

Downstream 100 bases:

>100_bases
AGAGGCGAGCGGGATTGTTTCCCGCTCTCTCAGATCGCCCTTTTCTACATTGCCGTAGGCGCGGTGACACCGAGGATCCT
GAAGCCGTTCTGCAGGACCT

Product: nicotinate (nicotinamide) nucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MRLALFGGSFDPPHNAHLALCLCARELLDIDKLIISVSNNPLKENRSASNAHRLAMAELLVSEINATGRIAEVSRWELER
SGPSYTIDLLTRIGQLYPEEPVTLLIGEDNFRGFRQWKSWQEILERCYVVVFRRPLEHAAFDDAYAHLPGIPDRHQVRFI
DFDFQLSSTAIRYAIATGEPYAHLVPPSIADYIASRHLYSERS

Sequences:

>Translated_203_residues
MRLALFGGSFDPPHNAHLALCLCARELLDIDKLIISVSNNPLKENRSASNAHRLAMAELLVSEINATGRIAEVSRWELER
SGPSYTIDLLTRIGQLYPEEPVTLLIGEDNFRGFRQWKSWQEILERCYVVVFRRPLEHAAFDDAYAHLPGIPDRHQVRFI
DFDFQLSSTAIRYAIATGEPYAHLVPPSIADYIASRHLYSERS
>Mature_203_residues
MRLALFGGSFDPPHNAHLALCLCARELLDIDKLIISVSNNPLKENRSASNAHRLAMAELLVSEINATGRIAEVSRWELER
SGPSYTIDLLTRIGQLYPEEPVTLLIGEDNFRGFRQWKSWQEILERCYVVVFRRPLEHAAFDDAYAHLPGIPDRHQVRFI
DFDFQLSSTAIRYAIATGEPYAHLVPPSIADYIASRHLYSERS

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=214, Percent_Identity=30.3738317757009, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_PROA2 (B4S6D9)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002016888.1
- ProteinModelPortal:   B4S6D9
- SMR:   B4S6D9
- GeneID:   6459651
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_2239
- HOGENOM:   HBG739448
- OMA:   IPPHKNT
- ProtClustDB:   CLSK637104
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR019450
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2; PF10362 DUF2432

EC number: =2.7.7.18

Molecular weight: Translated: 23120; Mature: 23120

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLALFGGSFDPPHNAHLALCLCARELLDIDKLIISVSNNPLKENRSASNAHRLAMAELL
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHH
VSEINATGRIAEVSRWELERSGPSYTIDLLTRIGQLYPEEPVTLLIGEDNFRGFRQWKSW
HHHHCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHH
QEILERCYVVVFRRPLEHAAFDDAYAHLPGIPDRHQVRFIDFDFQLSSTAIRYAIATGEP
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEEEECEECCCEEEEEEECCCC
YAHLVPPSIADYIASRHLYSERS
CEEECCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLALFGGSFDPPHNAHLALCLCARELLDIDKLIISVSNNPLKENRSASNAHRLAMAELL
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHH
VSEINATGRIAEVSRWELERSGPSYTIDLLTRIGQLYPEEPVTLLIGEDNFRGFRQWKSW
HHHHCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHH
QEILERCYVVVFRRPLEHAAFDDAYAHLPGIPDRHQVRFIDFDFQLSSTAIRYAIATGEP
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEEEECEECCCEEEEEEECCCC
YAHLVPPSIADYIASRHLYSERS
CEEECCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA