Click here to switch to the map view.

The map label for this gene is pyrD [H]

Identifier: 194335008

GI number: 194335008

Start: 2400657

End: 2401643

Strand: Reverse

Name: pyrD [H]

Synonym: Paes_2219

Alternate gene names: 194335008

Gene position: 2401643-2400657 (Counterclockwise)

Preceding gene: 194335009

Following gene: 194335007

Centisome position: 95.57

GC content: 49.54

Gene sequence:

>987_bases
ATGGCTGATCTATCAACAACATACATGGGTCTGAAGCTTCGCAATCCTGTTATTGCGGCAAGCTCGGGCATGACTGATTC
CGTAGAAAAGGTTACAGCGCTTGCTTCTGCAGGAGCGGGTGCTGTGGTTCTGAAATCGCTCTTTGAAGAACAGATTCGCA
ATGAATCGGAATATGCTATCGGGGCAAATGAACAGATGTACTATTACGCCGAGGCAGAAGACTATATTCGTGATTATACC
CGTGGAAATGATTTGCAGAAGTATCTCGACCTCGTTGCCGATTGCAAGGCCGCGGTCGATATCCCTGTCATTGCCAGTCT
GAACTGTGTTTCTTCTTCAGAGTGGACCAAATTTGCCAGCCAGATCCAGCGCGCGGGCGCAGACGCTCTGGAGCTCAATC
TTTTTATGCTTCCTTCCGATCCGCGTAAACAGAGCGTGCAGAATGAGGCGGTCTATTTCGATATTCTCAAGAGGATTCAG
GAAGATGTGAGTATTGCGGTATCGGCAAAGATCAGTTACTACTTTTCCGGTCTGGCAAACATGGCTACCCGGCTCGCTTC
GAGCGGTATCGGAGGTCTTGTTCTCTTTAACCGTTTTTTCTCGCCTGATATCGATATTGATACGTTTGAGATTACAAGCT
CAAATGTTTTCAGTTCTCCCGAGGATCTTTATCTCTCCCTTCGCTGGGTGGCCATGCTCTCTTCAATGGTGTCGTGCGAT
ATTGCCGCTTCTACCGGTATTCATGATAGTTCGGCCCTGATCAAGCAGCTTCTTGCCGGAGCAAAGGCCGGACAGATTGC
TTCCGTACTCTATCGCCAGGGGCCGGGGGTTATCGCTGCTATGCTTGAAGAGCTTGAAGGCTACATGCAGCGCCACGGTT
TTGCTGATCTGACGCAGGTCATAGGACGGATGAGCCTGCACAATGCAGGAAATCCCGCAGCATACGAGCGCGTTCAGTTT
ATGAAGTATTTCAGTGATATCCGGTGA

Upstream 100 bases:

>100_bases
CACAGAGTTTCGTATTTTCTCTCTATGACGTCCGGATGGAAGCATCCGGCGTTCATTTTTTTTCAATTTTTGTCCACATT
CGGTTTTCTGGAGTGATTTT

Downstream 100 bases:

>100_bases
TATGAAGAGCGTTTCCGCCATGTCGCCTTCTCTTTTCGATCTCAGTTATCCTCTGAGGGCTGACATGGCGGTCTATCCCG
GTACTCCTCCGGTTGTCCTC

Product: dihydroorotate dehydrogenase 2

Products: NA

Alternate protein names: DHOdehase; DHOD; DHODase; Dihydroorotate oxidase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MADLSTTYMGLKLRNPVIAASSGMTDSVEKVTALASAGAGAVVLKSLFEEQIRNESEYAIGANEQMYYYAEAEDYIRDYT
RGNDLQKYLDLVADCKAAVDIPVIASLNCVSSSEWTKFASQIQRAGADALELNLFMLPSDPRKQSVQNEAVYFDILKRIQ
EDVSIAVSAKISYYFSGLANMATRLASSGIGGLVLFNRFFSPDIDIDTFEITSSNVFSSPEDLYLSLRWVAMLSSMVSCD
IAASTGIHDSSALIKQLLAGAKAGQIASVLYRQGPGVIAAMLEELEGYMQRHGFADLTQVIGRMSLHNAGNPAAYERVQF
MKYFSDIR

Sequences:

>Translated_328_residues
MADLSTTYMGLKLRNPVIAASSGMTDSVEKVTALASAGAGAVVLKSLFEEQIRNESEYAIGANEQMYYYAEAEDYIRDYT
RGNDLQKYLDLVADCKAAVDIPVIASLNCVSSSEWTKFASQIQRAGADALELNLFMLPSDPRKQSVQNEAVYFDILKRIQ
EDVSIAVSAKISYYFSGLANMATRLASSGIGGLVLFNRFFSPDIDIDTFEITSSNVFSSPEDLYLSLRWVAMLSSMVSCD
IAASTGIHDSSALIKQLLAGAKAGQIASVLYRQGPGVIAAMLEELEGYMQRHGFADLTQVIGRMSLHNAGNPAAYERVQF
MKYFSDIR
>Mature_327_residues
ADLSTTYMGLKLRNPVIAASSGMTDSVEKVTALASAGAGAVVLKSLFEEQIRNESEYAIGANEQMYYYAEAEDYIRDYTR
GNDLQKYLDLVADCKAAVDIPVIASLNCVSSSEWTKFASQIQRAGADALELNLFMLPSDPRKQSVQNEAVYFDILKRIQE
DVSIAVSAKISYYFSGLANMATRLASSGIGGLVLFNRFFSPDIDIDTFEITSSNVFSSPEDLYLSLRWVAMLSSMVSCDI
AASTGIHDSSALIKQLLAGAKAGQIASVLYRQGPGVIAAMLEELEGYMQRHGFADLTQVIGRMSLHNAGNPAAYERVQFM
KYFSDIR

Specific function: Unknown

COG id: COG0167

COG function: function code F; Dihydroorotate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005720
- InterPro:   IPR012135
- InterPro:   IPR001295 [H]

Pfam domain/function: PF01180 DHO_dh [H]

EC number: =1.3.3.1 [H]

Molecular weight: Translated: 35880; Mature: 35749

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLSTTYMGLKLRNPVIAASSGMTDSVEKVTALASAGAGAVVLKSLFEEQIRNESEYAI
CCCCCCHHCCEEECCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEE
GANEQMYYYAEAEDYIRDYTRGNDLQKYLDLVADCKAAVDIPVIASLNCVSSSEWTKFAS
CCCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHEECCCCCCHHHHHHHH
QIQRAGADALELNLFMLPSDPRKQSVQNEAVYFDILKRIQEDVSIAVSAKISYYFSGLAN
HHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHH
MATRLASSGIGGLVLFNRFFSPDIDIDTFEITSSNVFSSPEDLYLSLRWVAMLSSMVSCD
HHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IAASTGIHDSSALIKQLLAGAKAGQIASVLYRQGPGVIAAMLEELEGYMQRHGFADLTQV
HHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHH
IGRMSLHNAGNPAAYERVQFMKYFSDIR
HHHHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADLSTTYMGLKLRNPVIAASSGMTDSVEKVTALASAGAGAVVLKSLFEEQIRNESEYAI
CCCCCHHCCEEECCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEE
GANEQMYYYAEAEDYIRDYTRGNDLQKYLDLVADCKAAVDIPVIASLNCVSSSEWTKFAS
CCCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHEECCCCCCHHHHHHHH
QIQRAGADALELNLFMLPSDPRKQSVQNEAVYFDILKRIQEDVSIAVSAKISYYFSGLAN
HHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHH
MATRLASSGIGGLVLFNRFFSPDIDIDTFEITSSNVFSSPEDLYLSLRWVAMLSSMVSCD
HHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IAASTGIHDSSALIKQLLAGAKAGQIASVLYRQGPGVIAAMLEELEGYMQRHGFADLTQV
HHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHH
IGRMSLHNAGNPAAYERVQFMKYFSDIR
HHHHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11121031 [H]