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The map label for this gene is kynB [H]

Identifier: 194335007

GI number: 194335007

Start: 2399996

End: 2400655

Strand: Reverse

Name: kynB [H]

Synonym: Paes_2218

Alternate gene names: 194335007

Gene position: 2400655-2399996 (Counterclockwise)

Preceding gene: 194335008

Following gene: 194335005

Centisome position: 95.53

GC content: 53.03

Gene sequence:

>660_bases
ATGAAGAGCGTTTCCGCCATGTCGCCTTCTCTTTTCGATCTCAGTTATCCTCTGAGGGCTGACATGGCGGTCTATCCCGG
TACTCCTCCGGTTGTCCTCAAGCCGCTCTGCACGATTGAGCTGGATGGTTTTGCTGAAAACCGTTTGGAGATATCGTCGC
ATACCGGAACTCATATCGATGCCCCGGCCCACATGCTCTCAGGAGGAAGAACCCTCGACAGTTATCCTCTTTCCTCCTTT
GAGGGAAGAGCGCTTGTCATTGATTGCTCTTCGTTGCCGGCCTCCCGGATAACCCTTTCCGATCTGCATCCTTTTGCGAC
AGGTATCAAGGGGGTCGATTTTGTGCTGCTGTCGACAGGATGGGCCCGGTTCTGGGGTCATGAACGCTATTTTCATGATT
ACCCCGTGCTTCACGAAGATGCAGCACGTTGGCTGTCGGGGTTTACTCTCAGGGGCATCGGTGTCGATGCCATATCGGTC
GATGCGTCTGATGCCGAAAACTTTCCGATTCATCACATCCTGCTCGAAGCAGGCCTCCTTCTTATCGAAAATCTTGTGTC
TCTTTCGTCACTGGCAGGACGCTCCTTCCGTTTTACCTGTTTGCCTTTACCCATCGAATCGGCAGAAGCCGCTCCTGTGA
GAGCGGTAGCATATCTCTGA

Upstream 100 bases:

>100_bases
CTGACGCAGGTCATAGGACGGATGAGCCTGCACAATGCAGGAAATCCCGCAGCATACGAGCGCGTTCAGTTTATGAAGTA
TTTCAGTGATATCCGGTGAT

Downstream 100 bases:

>100_bases
ATGCAGAAAGCCTCCCTGATCGGGAGGCTTTCTGCATTTTATATATTCAGCGTTTAGTTCGATGCGACCATTGCCGGGCT
CTGAAGCTGAACGATAACGT

Product: cyclase family protein

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKSVSAMSPSLFDLSYPLRADMAVYPGTPPVVLKPLCTIELDGFAENRLEISSHTGTHIDAPAHMLSGGRTLDSYPLSSF
EGRALVIDCSSLPASRITLSDLHPFATGIKGVDFVLLSTGWARFWGHERYFHDYPVLHEDAARWLSGFTLRGIGVDAISV
DASDAENFPIHHILLEAGLLLIENLVSLSSLAGRSFRFTCLPLPIESAEAAPVRAVAYL

Sequences:

>Translated_219_residues
MKSVSAMSPSLFDLSYPLRADMAVYPGTPPVVLKPLCTIELDGFAENRLEISSHTGTHIDAPAHMLSGGRTLDSYPLSSF
EGRALVIDCSSLPASRITLSDLHPFATGIKGVDFVLLSTGWARFWGHERYFHDYPVLHEDAARWLSGFTLRGIGVDAISV
DASDAENFPIHHILLEAGLLLIENLVSLSSLAGRSFRFTCLPLPIESAEAAPVRAVAYL
>Mature_219_residues
MKSVSAMSPSLFDLSYPLRADMAVYPGTPPVVLKPLCTIELDGFAENRLEISSHTGTHIDAPAHMLSGGRTLDSYPLSSF
EGRALVIDCSSLPASRITLSDLHPFATGIKGVDFVLLSTGWARFWGHERYFHDYPVLHEDAARWLSGFTLRGIGVDAISV
DASDAENFPIHHILLEAGLLLIENLVSLSSLAGRSFRFTCLPLPIESAEAAPVRAVAYL

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 23779; Mature: 23779

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVSAMSPSLFDLSYPLRADMAVYPGTPPVVLKPLCTIELDGFAENRLEISSHTGTHID
CCCCCCCCCCEEECCCCCCCCEEEECCCCCEEECCEEEEEECCCCCCEEEEECCCCCCCC
APAHMLSGGRTLDSYPLSSFEGRALVIDCSSLPASRITLSDLHPFATGIKGVDFVLLSTG
CCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEHHHCCHHHHCCCCCEEEEECCC
WARFWGHERYFHDYPVLHEDAARWLSGFTLRGIGVDAISVDASDAENFPIHHILLEAGLL
HHHHCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHH
LIENLVSLSSLAGRSFRFTCLPLPIESAEAAPVRAVAYL
HHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECC
>Mature Secondary Structure
MKSVSAMSPSLFDLSYPLRADMAVYPGTPPVVLKPLCTIELDGFAENRLEISSHTGTHID
CCCCCCCCCCEEECCCCCCCCEEEECCCCCEEECCEEEEEECCCCCCEEEEECCCCCCCC
APAHMLSGGRTLDSYPLSSFEGRALVIDCSSLPASRITLSDLHPFATGIKGVDFVLLSTG
CCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEHHHCCHHHHCCCCCEEEEECCC
WARFWGHERYFHDYPVLHEDAARWLSGFTLRGIGVDAISVDASDAENFPIHHILLEAGLL
HHHHCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHH
LIENLVSLSSLAGRSFRFTCLPLPIESAEAAPVRAVAYL
HHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA