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The map label for this gene is prtE [H]

Identifier: 194334993

GI number: 194334993

Start: 2377035

End: 2378213

Strand: Reverse

Name: prtE [H]

Synonym: Paes_2204

Alternate gene names: 194334993

Gene position: 2378213-2377035 (Counterclockwise)

Preceding gene: 194334994

Following gene: 194334992

Centisome position: 94.64

GC content: 57.51

Gene sequence:

>1179_bases
ATGAGTACAGAGCCTTCAGATTTCTTACCGGAAAACAGTAGCGACAAGAAGCAGAGCACATCCTCCGCGACGTTCTGGAA
AACATCAGGCTCGATGCGCATCGGCATTATGGTGCTGCTCGCAGGTTTCGGCGCTTTTCTTCTCTGGGCGGCGCTGGCTC
CGCTTGATGAAGGCGTGCCGTGTACCGGAGCGGTCAGTATCTCCACCCGAAGCAAGGTGGTCCAGCATCTGAAGGGGGGA
ATTGTCCATTCGGTCAACGTGCGCGAAGGGCAGATGGTTGGAAAAGATGATCTTCTTATGACACTGTCCGATCAGGAGAC
CCTTGCCCGCTACAGGGAGGTTTATCAGCACTATCTCGGCTTGCGGGCGGCCGAAAGCAGACTTCTGGCTGAAGAGCGGG
GAGCATCATCAATCACCTTTCATCCCGATCTGCTGCGTTCGCCCGATACCGCGCTGGCCGCTGAGATGATGGCAACGCAG
CGGGAGCTTTTTACTGCCCGACAGCAAGCCATGCGTTCGGTGTGTGAGCGGCTGAAAGGGGTGCGTGCTATGGTTTCTGA
AGGCTATGCACCGCGATACCAGCAACTGGAGCTTGAGGGGCACCTTGCGGAGCTGCAGTCTCAGCGGGCATCCGAGATGG
CCGCTGTGCAGGTTGCTGTCGATGCCTGGCAGGAAAAAACCGCCGCCCTGCATGATGAACTGGAGCGAACCGGTATCCGC
TCTCCTGCTTCCGGACAGGTCGTTGGTCTGCAGGTACAGACGGTCGGAGCGGTGATCTCTCCCGGTGAAAAGATCATGGA
TATCGTTCCGCTTGATGAAAAGCTGCTGGTTGAGGTCCGAGTAGCGCCTCACCTGATTGACAGGGTGCACTCTGGTCTTC
CGGCGGATATGCGTTTTGCTTCGTTTGCGCACTCTCCTATGCTCATGGTTGGTGGTGTGGTCGAGTCGGTCTCCCATGAC
CTGATTACTGACCCGAAGATGAATCCTGTGATGCCGGGGGCGACCTACTATCTCGCCCGGGTAGCGTTGACTCCCGAAGG
CATTGCGTCACTCGGCAGCAGGAAACTGCAGGCAGGCATGCCGGTGCAGACGGTGATCCGTACCGGTGAACGCACGCTGC
TGACCTATCTGCTGCATCCGCTGGTCAAACGGATAACCGCATCTTTGAAGGAGGAGTAG

Upstream 100 bases:

>100_bases
TGCATGAGGGACATATTTCCCTCGACGGACCTCGTGACGACGTGATGAAAACAATGATAGCAAGAAAAACGGCATCAAAG
CCGGCAGAGAAAACCAGATT

Downstream 100 bases:

>100_bases
GAAGATGACCAAACCATTGATGTTACTGATGCTTTCTGTCCTCTGCGGGCTCGGGAGCGCATCGGCTGAATCGCTTGATC
TTCGGGGTGCATGGGAGCAG

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSTEPSDFLPENSSDKKQSTSSATFWKTSGSMRIGIMVLLAGFGAFLLWAALAPLDEGVPCTGAVSISTRSKVVQHLKGG
IVHSVNVREGQMVGKDDLLMTLSDQETLARYREVYQHYLGLRAAESRLLAEERGASSITFHPDLLRSPDTALAAEMMATQ
RELFTARQQAMRSVCERLKGVRAMVSEGYAPRYQQLELEGHLAELQSQRASEMAAVQVAVDAWQEKTAALHDELERTGIR
SPASGQVVGLQVQTVGAVISPGEKIMDIVPLDEKLLVEVRVAPHLIDRVHSGLPADMRFASFAHSPMLMVGGVVESVSHD
LITDPKMNPVMPGATYYLARVALTPEGIASLGSRKLQAGMPVQTVIRTGERTLLTYLLHPLVKRITASLKEE

Sequences:

>Translated_392_residues
MSTEPSDFLPENSSDKKQSTSSATFWKTSGSMRIGIMVLLAGFGAFLLWAALAPLDEGVPCTGAVSISTRSKVVQHLKGG
IVHSVNVREGQMVGKDDLLMTLSDQETLARYREVYQHYLGLRAAESRLLAEERGASSITFHPDLLRSPDTALAAEMMATQ
RELFTARQQAMRSVCERLKGVRAMVSEGYAPRYQQLELEGHLAELQSQRASEMAAVQVAVDAWQEKTAALHDELERTGIR
SPASGQVVGLQVQTVGAVISPGEKIMDIVPLDEKLLVEVRVAPHLIDRVHSGLPADMRFASFAHSPMLMVGGVVESVSHD
LITDPKMNPVMPGATYYLARVALTPEGIASLGSRKLQAGMPVQTVIRTGERTLLTYLLHPLVKRITASLKEE
>Mature_391_residues
STEPSDFLPENSSDKKQSTSSATFWKTSGSMRIGIMVLLAGFGAFLLWAALAPLDEGVPCTGAVSISTRSKVVQHLKGGI
VHSVNVREGQMVGKDDLLMTLSDQETLARYREVYQHYLGLRAAESRLLAEERGASSITFHPDLLRSPDTALAAEMMATQR
ELFTARQQAMRSVCERLKGVRAMVSEGYAPRYQQLELEGHLAELQSQRASEMAAVQVAVDAWQEKTAALHDELERTGIRS
PASGQVVGLQVQTVGAVISPGEKIMDIVPLDEKLLVEVRVAPHLIDRVHSGLPADMRFASFAHSPMLMVGGVVESVSHDL
ITDPKMNPVMPGATYYLARVALTPEGIASLGSRKLQAGMPVQTVIRTGERTLLTYLLHPLVKRITASLKEE

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42725; Mature: 42594

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEPSDFLPENSSDKKQSTSSATFWKTSGSMRIGIMVLLAGFGAFLLWAALAPLDEGVP
CCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
CTGAVSISTRSKVVQHLKGGIVHSVNVREGQMVGKDDLLMTLSDQETLARYREVYQHYLG
CCCEEECHHHHHHHHHHCCCCEEEEECCCCCEECCCCEEEEECCHHHHHHHHHHHHHHHH
LRAAESRLLAEERGASSITFHPDLLRSPDTALAAEMMATQRELFTARQQAMRSVCERLKG
HHHHHHHHHHHHCCCCEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRAMVSEGYAPRYQQLELEGHLAELQSQRASEMAAVQVAVDAWQEKTAALHDELERTGIR
HHHHHHCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPASGQVVGLQVQTVGAVISPGEKIMDIVPLDEKLLVEVRVAPHLIDRVHSGLPADMRFA
CCCCCCEEEEEEEEHHHHCCCCHHHHEECCCCHHHEEEHHHHHHHHHHHHCCCCCCHHHH
SFAHSPMLMVGGVVESVSHDLITDPKMNPVMPGATYYLARVALTPEGIASLGSRKLQAGM
HHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCHHHHCCC
PVQTVIRTGERTLLTYLLHPLVKRITASLKEE
CHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STEPSDFLPENSSDKKQSTSSATFWKTSGSMRIGIMVLLAGFGAFLLWAALAPLDEGVP
CCCCCCCCCCCCCCHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
CTGAVSISTRSKVVQHLKGGIVHSVNVREGQMVGKDDLLMTLSDQETLARYREVYQHYLG
CCCEEECHHHHHHHHHHCCCCEEEEECCCCCEECCCCEEEEECCHHHHHHHHHHHHHHHH
LRAAESRLLAEERGASSITFHPDLLRSPDTALAAEMMATQRELFTARQQAMRSVCERLKG
HHHHHHHHHHHHCCCCEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRAMVSEGYAPRYQQLELEGHLAELQSQRASEMAAVQVAVDAWQEKTAALHDELERTGIR
HHHHHHCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPASGQVVGLQVQTVGAVISPGEKIMDIVPLDEKLLVEVRVAPHLIDRVHSGLPADMRFA
CCCCCCEEEEEEEEHHHHCCCCHHHHEECCCCHHHEEEHHHHHHHHHHHHCCCCCCHHHH
SFAHSPMLMVGGVVESVSHDLITDPKMNPVMPGATYYLARVALTPEGIASLGSRKLQAGM
HHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCHHHHCCC
PVQTVIRTGERTLLTYLLHPLVKRITASLKEE
CHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]