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The map label for this gene is nqrA [H]

Identifier: 194334929

GI number: 194334929

Start: 2313364

End: 2314710

Strand: Reverse

Name: nqrA [H]

Synonym: Paes_2138

Alternate gene names: 194334929

Gene position: 2314710-2313364 (Counterclockwise)

Preceding gene: 194334934

Following gene: 194334928

Centisome position: 92.11

GC content: 51.52

Gene sequence:

>1347_bases
ATGAGTGTGATCAGAATCAGGAAAGGTCATGACCTCAATATCCTGGGTGTTCCGGAAAAAAAACTTCAACATCTGCAACG
GCCGGTTCGGCTTGAGCTTTGTCCCCTTGATTTCAGAGGAATCAAACCAAAACTGCTTGTCCGCGAAGGGGAGCGCGTTA
ATGCGGGAGGTGCGGTATACCGCGATAAAGGTCGTCCCGACATCCTGTTTACATCACCGGCATCCGGAACGATCTCCTCA
ATAGCCTATGGCGAGCGTCGTACGATAACCGGCATAACCATCGATCTTGACAAGAGCGATATCTTTGAGGATTTTCGAGT
CTCCGATGCAGACCATTCCGACCCCTCCTCCATCCGTTCTCTGCTGCTTAAGTCAGGCCTCTGGCCTGTGATCCGACAGA
GACCTTTTTCGGGCATTGCCGATCCTGATGTCTCGCCCAAGGCGGTTTTTGTTCCTGCAATGCCGACCGCGCCGTTTGCT
CCGGATATCTTCATGCAGCTTGACGGAAAAGATCGTGCTTTTCAATCCGGGCTGACTCTGCTTGCTCGTCTGACTGGCAG
CCCGGTTCATCTGGTTATCGATGAAAAGAATTCTTCTCCTCTTTTTACCGGCGCTGAAGATGTTATCCTGCACCGTTTCA
GCGGTCCGCATCCGGCCGGTAATGTCGGGATCCATATTCACCACATAGCGCCAATCCGGCATCGAGATGATCATGTCTGG
TATGTTCTGCCCCAGGACGTTGCGCGTATCGGAGCGTTCTTTCTGACAGGGAGGCTTCCGGTTACAAAAGTGATGACTGT
AGGGGGAGAGGCGGTAGAGCAACGCCAGTATCTCGGTTTTATGCAGGGGTCTCTCATCGGCGATATTCTTGAGGGTAACC
CTGTCAGCGAGCCTGCGCGCATCATTTCCGGAGATGTGCTTACCGGAACCCGCAGGGATCTGCAGAAGCCTATCGGGTTC
TATGATGAAGTCGTCTCGGTGATTCCTGAAAAAACCGGTCGTGATTTCATTGGCTGGCTGAGTCCGGGGATGAGAAAGTA
TTCAGTGACCAATCTCTTTCTTTCCCGCTTGTTTCCGTCCGGGTCGTTCAGTCTCGATACCGGCCTCAACGGCAGTGAGC
GGGTGATGATACCCTTCGGCAATATCGAGTCGGTGCTCCCGATTGATATCATTCCGACGTGGCTGATTAAAATGATTATC
GCAAGAGATATCGACGAAATGGAAAAACTTGGCATTTACGAGTGCGACCCGGAAGATTTTGCCTTGTGCTCGTTTGTCGA
TGCCTCAAAAATGGAAATCGTGGACATTATCCGCGACGGTCTGGACTATATTGAAAAGAACGGATAA

Upstream 100 bases:

>100_bases
TTTTGTCTATAGTTGTTGTTCTGCTGTGTTCATGATGGTGTAATGTGTATTTTTGACCAATCTTTCAGTTCTTCAGAACC
GATTCGGAGAAGTGTGGCGT

Downstream 100 bases:

>100_bases
TCTATGAGCGTATTGCGTAGCCTTCTTGACAGGGTAGAACCACATTTCAGTAAAGGCGGCCGTTTTTCACGATTTGGCGC
TCTCTATGAAATAGTCGATA

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MSVIRIRKGHDLNILGVPEKKLQHLQRPVRLELCPLDFRGIKPKLLVREGERVNAGGAVYRDKGRPDILFTSPASGTISS
IAYGERRTITGITIDLDKSDIFEDFRVSDADHSDPSSIRSLLLKSGLWPVIRQRPFSGIADPDVSPKAVFVPAMPTAPFA
PDIFMQLDGKDRAFQSGLTLLARLTGSPVHLVIDEKNSSPLFTGAEDVILHRFSGPHPAGNVGIHIHHIAPIRHRDDHVW
YVLPQDVARIGAFFLTGRLPVTKVMTVGGEAVEQRQYLGFMQGSLIGDILEGNPVSEPARIISGDVLTGTRRDLQKPIGF
YDEVVSVIPEKTGRDFIGWLSPGMRKYSVTNLFLSRLFPSGSFSLDTGLNGSERVMIPFGNIESVLPIDIIPTWLIKMII
ARDIDEMEKLGIYECDPEDFALCSFVDASKMEIVDIIRDGLDYIEKNG

Sequences:

>Translated_448_residues
MSVIRIRKGHDLNILGVPEKKLQHLQRPVRLELCPLDFRGIKPKLLVREGERVNAGGAVYRDKGRPDILFTSPASGTISS
IAYGERRTITGITIDLDKSDIFEDFRVSDADHSDPSSIRSLLLKSGLWPVIRQRPFSGIADPDVSPKAVFVPAMPTAPFA
PDIFMQLDGKDRAFQSGLTLLARLTGSPVHLVIDEKNSSPLFTGAEDVILHRFSGPHPAGNVGIHIHHIAPIRHRDDHVW
YVLPQDVARIGAFFLTGRLPVTKVMTVGGEAVEQRQYLGFMQGSLIGDILEGNPVSEPARIISGDVLTGTRRDLQKPIGF
YDEVVSVIPEKTGRDFIGWLSPGMRKYSVTNLFLSRLFPSGSFSLDTGLNGSERVMIPFGNIESVLPIDIIPTWLIKMII
ARDIDEMEKLGIYECDPEDFALCSFVDASKMEIVDIIRDGLDYIEKNG
>Mature_447_residues
SVIRIRKGHDLNILGVPEKKLQHLQRPVRLELCPLDFRGIKPKLLVREGERVNAGGAVYRDKGRPDILFTSPASGTISSI
AYGERRTITGITIDLDKSDIFEDFRVSDADHSDPSSIRSLLLKSGLWPVIRQRPFSGIADPDVSPKAVFVPAMPTAPFAP
DIFMQLDGKDRAFQSGLTLLARLTGSPVHLVIDEKNSSPLFTGAEDVILHRFSGPHPAGNVGIHIHHIAPIRHRDDHVWY
VLPQDVARIGAFFLTGRLPVTKVMTVGGEAVEQRQYLGFMQGSLIGDILEGNPVSEPARIISGDVLTGTRRDLQKPIGFY
DEVVSVIPEKTGRDFIGWLSPGMRKYSVTNLFLSRLFPSGSFSLDTGLNGSERVMIPFGNIESVLPIDIIPTWLIKMIIA
RDIDEMEKLGIYECDPEDFALCSFVDASKMEIVDIIRDGLDYIEKNG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 49600; Mature: 49469

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIRIRKGHDLNILGVPEKKLQHLQRPVRLELCPLDFRGIKPKLLVREGERVNAGGAVY
CCEEEEECCCCEEEEECCHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCEECCCCCEE
RDKGRPDILFTSPASGTISSIAYGERRTITGITIDLDKSDIFEDFRVSDADHSDPSSIRS
ECCCCCCEEEECCCCCCHHHHCCCCCEEEEEEEEECCHHHHHHHHCCCCCCCCCHHHHHH
LLLKSGLWPVIRQRPFSGIADPDVSPKAVFVPAMPTAPFAPDIFMQLDGKDRAFQSGLTL
HHHHCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHH
LARLTGSPVHLVIDEKNSSPLFTGAEDVILHRFSGPHPAGNVGIHIHHIAPIRHRDDHVW
HHHHCCCCEEEEEECCCCCCCCCCHHHHHEEECCCCCCCCCCCEEEEEECCCEECCCCEE
YVLPQDVARIGAFFLTGRLPVTKVMTVGGEAVEQRQYLGFMQGSLIGDILEGNPVSEPAR
EECCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
IISGDVLTGTRRDLQKPIGFYDEVVSVIPEKTGRDFIGWLSPGMRKYSVTNLFLSRLFPS
HHCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCC
GSFSLDTGLNGSERVMIPFGNIESVLPIDIIPTWLIKMIIARDIDEMEKLGIYECDPEDF
CCEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHHHHCCCEECCCCCC
ALCSFVDASKMEIVDIIRDGLDYIEKNG
EEEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVIRIRKGHDLNILGVPEKKLQHLQRPVRLELCPLDFRGIKPKLLVREGERVNAGGAVY
CEEEEECCCCEEEEECCHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCEECCCCCEE
RDKGRPDILFTSPASGTISSIAYGERRTITGITIDLDKSDIFEDFRVSDADHSDPSSIRS
ECCCCCCEEEECCCCCCHHHHCCCCCEEEEEEEEECCHHHHHHHHCCCCCCCCCHHHHHH
LLLKSGLWPVIRQRPFSGIADPDVSPKAVFVPAMPTAPFAPDIFMQLDGKDRAFQSGLTL
HHHHCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHH
LARLTGSPVHLVIDEKNSSPLFTGAEDVILHRFSGPHPAGNVGIHIHHIAPIRHRDDHVW
HHHHCCCCEEEEEECCCCCCCCCCHHHHHEEECCCCCCCCCCCEEEEEECCCEECCCCEE
YVLPQDVARIGAFFLTGRLPVTKVMTVGGEAVEQRQYLGFMQGSLIGDILEGNPVSEPAR
EECCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
IISGDVLTGTRRDLQKPIGFYDEVVSVIPEKTGRDFIGWLSPGMRKYSVTNLFLSRLFPS
HHCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCC
GSFSLDTGLNGSERVMIPFGNIESVLPIDIIPTWLIKMIIARDIDEMEKLGIYECDPEDF
CCEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHHHHCCCEECCCCCC
ALCSFVDASKMEIVDIIRDGLDYIEKNG
EEEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA