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The map label for this gene is fkpB [C]

Identifier: 194334730

GI number: 194334730

Start: 2113950

End: 2114378

Strand: Reverse

Name: fkpB [C]

Synonym: Paes_1931

Alternate gene names: 194334730

Gene position: 2114378-2113950 (Counterclockwise)

Preceding gene: 194334732

Following gene: 194334729

Centisome position: 84.14

GC content: 52.91

Gene sequence:

>429_bases
ATGGCTGAAGCCAAACAGGGAGATAAGGTAAAAGTTCATTATACAGGGAAGCTCAACGACGGGAGCGTGTTTGATTCATC
GGTTGAACGCGATCCTCTGGAGTTTACTATCGGCGAAGGTGCTGTGATACCGGGGTTTGAACAGGCGGTAGTGGGTCTTC
AGCCCGGTGATTCGACTGAGACAACCATTGAAGCGGCAAATGCATACGGCAACCATAGCCATGAGCTCATAACAGAGGTT
CCTCGCGAACGTATGCCCCGGGACCTCCAGGTCACTATCGGCCAGCAGCTTCAGGTCAGCATGGCCAACGGCCAGACGGC
CGTTGTGATGGTGACTGATATGACCGATACGGCGGTGACCATCGACGCCAATCATCCTCTTGCAGGTCAGGACCTGACCT
TTTCGATTGAGTTAGTTGAAATTGCCTGA

Upstream 100 bases:

>100_bases
ATGATTGATTGTTATCCAGAGCATTGCAGGTCGATGTTCAGGTGATGGTTGATTGAAAACGACAGATTTTTGTTGAAACA
GAAAAAGAGGAGGACATCTC

Downstream 100 bases:

>100_bases
TTGTTTCGCCTCCCTTTACTCCCTTTTCAGGGAGCGAAGGGAGGTTCTCTCACCTTTTTATTCTGCGCCCGGTTATGTTG
AAAAACCTGTCTGGAGTATT

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MAEAKQGDKVKVHYTGKLNDGSVFDSSVERDPLEFTIGEGAVIPGFEQAVVGLQPGDSTETTIEAANAYGNHSHELITEV
PRERMPRDLQVTIGQQLQVSMANGQTAVVMVTDMTDTAVTIDANHPLAGQDLTFSIELVEIA

Sequences:

>Translated_142_residues
MAEAKQGDKVKVHYTGKLNDGSVFDSSVERDPLEFTIGEGAVIPGFEQAVVGLQPGDSTETTIEAANAYGNHSHELITEV
PRERMPRDLQVTIGQQLQVSMANGQTAVVMVTDMTDTAVTIDANHPLAGQDLTFSIELVEIA
>Mature_141_residues
AEAKQGDKVKVHYTGKLNDGSVFDSSVERDPLEFTIGEGAVIPGFEQAVVGLQPGDSTETTIEAANAYGNHSHELITEVP
RERMPRDLQVTIGQQLQVSMANGQTAVVMVTDMTDTAVTIDANHPLAGQDLTFSIELVEIA

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786211, Length=143, Percent_Identity=32.8671328671329, Blast_Score=76, Evalue=8e-16,
Organism=Escherichia coli, GI1789748, Length=132, Percent_Identity=31.8181818181818, Blast_Score=72, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320727, Length=74, Percent_Identity=45.945945945946, Blast_Score=64, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24655568, Length=71, Percent_Identity=46.4788732394366, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15225; Mature: 15094

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAKQGDKVKVHYTGKLNDGSVFDSSVERDPLEFTIGEGAVIPGFEQAVVGLQPGDSTE
CCCCCCCCEEEEEEEEECCCCCEECCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCC
TTIEAANAYGNHSHELITEVPRERMPRDLQVTIGQQLQVSMANGQTAVVMVTDMTDTAVT
EEEEECCCCCCCCHHHHHHCHHHHCCCEEEEEECCEEEEEECCCCEEEEEEEECCCCEEE
IDANHPLAGQDLTFSIELVEIA
EECCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
AEAKQGDKVKVHYTGKLNDGSVFDSSVERDPLEFTIGEGAVIPGFEQAVVGLQPGDSTE
CCCCCCCEEEEEEEEECCCCCEECCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCC
TTIEAANAYGNHSHELITEVPRERMPRDLQVTIGQQLQVSMANGQTAVVMVTDMTDTAVT
EEEEECCCCCCCCHHHHHHCHHHHCCCEEEEEECCEEEEEECCCCEEEEEEEECCCCEEE
IDANHPLAGQDLTFSIELVEIA
EECCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]