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The map label for this gene is yhfN [H]

Identifier: 194334410

GI number: 194334410

Start: 1749450

End: 1750688

Strand: Reverse

Name: yhfN [H]

Synonym: Paes_1605

Alternate gene names: 194334410

Gene position: 1750688-1749450 (Counterclockwise)

Preceding gene: 194334411

Following gene: 194334409

Centisome position: 69.67

GC content: 46.81

Gene sequence:

>1239_bases
ATGAATGTTTTTGGTGTTATTATTTTCTCAACCCTTTTTTTTACTTTTCTGCTCAGAATTGTTGCCAATGTTGTCAACCT
TCGCTTCGCAGGAGCGGGACTTCCTGATGAGTTCAAGGGTGTTTTCGATGGGAAAGCCTATGAGAAGTCTCAGCGTTATC
TTCGTAAGAACACTGCTTTTTCGATGGTGAGCGGTGGTTTTGATCTGGCGGTTCTTCTGATTTTCTGGTTTTCAGGTGGT
TTTGGCGCTATCGATACCGTTGTAAGAGGTTTTGGTCAGTCCTCGATCGTAACCGGTCTTCTGTTTTTCGGAGTGCTGCT
GCTTTTTCAGAGCCTGATCTCTCTCCCTTTTACGCTCTACAGAATATTTGTGATCGAAGAGAAATTCGGTTTTAATAAAA
CGACTCCCTCGACGTTTATCGTCGATACCCTCAAATCGGTTGTTCTTGGTGTGACGCTTGGCGGTCCGGTGCTTGCCGCT
CTGCTCTGGTTTTTCGAGTACACGGGGGCTATGGCCTGGCTCTGGGCCTGGGCGGGAATAACTTTTTTCAGCCTCCTGCT
TCAGTATGCGGCACCTTCTCTCATCATGCCTCTTTTCAATCGTTTTACGCCGCTTGAGGACGGAGAACTCAAGTCTGCTA
TCATGCGCTACGCCAAAAGCGTCGGGTTTCCTCTTGAGGGGATTTATGTGATTGACGGCTCGAGGCGCTCCTCCAAAGCC
AACGCATTTTTTACCGGATTTGGCCGCCAGAAACGTATTGCTCTCTTCGATACGCTCATCGAACAGCACAGTGTCGAGGA
ACTTGTCGCTGTACTTGCTCATGAGATCGGACATTACAAAAAAAAGCACATTCTTATTTCCATGGTGCTTAATGCGCTCA
ATACAGGCGTCATATTTTTTCTCCTCTCGGTCTTTATGAACAACCGCCTGCTGTTTGACGCCTTTTATGTGCAGGAGACA
TCGGTCTATGCCAGTCTCGTCTTTTTTTTCCTCCTCTATAGTCCGATTGAGTTTTTATTGTCTATCGTTTTGCAGATGCT
TTCGAGAAAGCATGAATTCGAAGCAGATTACTATGCTGCAACCACCTATAGCAATGGAGGCGCTCTGGTTGATGCTTTGA
AAAAACTCTCGCGCAGCAGCCTGTCGAACCTTACGCCTCACCCTTTCTATGTGTTTCTCAATTATTCACATCCGCCCGTT
CTGGAGCGGATACGTCGCATCACGAACGTTACCTCATAA

Upstream 100 bases:

>100_bases
AAAAATAGCTGAAGGGAAGCAGAATCCTGAAGCGTGAAGAGATGATCTCTCTGTCTGTCTTAATGAACGGTATCTGTTGA
CCAGCAAATCCATTGATGGT

Downstream 100 bases:

>100_bases
CCTATCATAATGACGACATCCCGCTATTCTATGCCTGCGGAGTGGGCAGCGCATGATGCGACCTGGCTCTCATGGCCTCA
CAAGGAGGCTTCATGGCCTG

Product: Ste24 endopeptidase

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MNVFGVIIFSTLFFTFLLRIVANVVNLRFAGAGLPDEFKGVFDGKAYEKSQRYLRKNTAFSMVSGGFDLAVLLIFWFSGG
FGAIDTVVRGFGQSSIVTGLLFFGVLLLFQSLISLPFTLYRIFVIEEKFGFNKTTPSTFIVDTLKSVVLGVTLGGPVLAA
LLWFFEYTGAMAWLWAWAGITFFSLLLQYAAPSLIMPLFNRFTPLEDGELKSAIMRYAKSVGFPLEGIYVIDGSRRSSKA
NAFFTGFGRQKRIALFDTLIEQHSVEELVAVLAHEIGHYKKKHILISMVLNALNTGVIFFLLSVFMNNRLLFDAFYVQET
SVYASLVFFFLLYSPIEFLLSIVLQMLSRKHEFEADYYAATTYSNGGALVDALKKLSRSSLSNLTPHPFYVFLNYSHPPV
LERIRRITNVTS

Sequences:

>Translated_412_residues
MNVFGVIIFSTLFFTFLLRIVANVVNLRFAGAGLPDEFKGVFDGKAYEKSQRYLRKNTAFSMVSGGFDLAVLLIFWFSGG
FGAIDTVVRGFGQSSIVTGLLFFGVLLLFQSLISLPFTLYRIFVIEEKFGFNKTTPSTFIVDTLKSVVLGVTLGGPVLAA
LLWFFEYTGAMAWLWAWAGITFFSLLLQYAAPSLIMPLFNRFTPLEDGELKSAIMRYAKSVGFPLEGIYVIDGSRRSSKA
NAFFTGFGRQKRIALFDTLIEQHSVEELVAVLAHEIGHYKKKHILISMVLNALNTGVIFFLLSVFMNNRLLFDAFYVQET
SVYASLVFFFLLYSPIEFLLSIVLQMLSRKHEFEADYYAATTYSNGGALVDALKKLSRSSLSNLTPHPFYVFLNYSHPPV
LERIRRITNVTS
>Mature_412_residues
MNVFGVIIFSTLFFTFLLRIVANVVNLRFAGAGLPDEFKGVFDGKAYEKSQRYLRKNTAFSMVSGGFDLAVLLIFWFSGG
FGAIDTVVRGFGQSSIVTGLLFFGVLLLFQSLISLPFTLYRIFVIEEKFGFNKTTPSTFIVDTLKSVVLGVTLGGPVLAA
LLWFFEYTGAMAWLWAWAGITFFSLLLQYAAPSLIMPLFNRFTPLEDGELKSAIMRYAKSVGFPLEGIYVIDGSRRSSKA
NAFFTGFGRQKRIALFDTLIEQHSVEELVAVLAHEIGHYKKKHILISMVLNALNTGVIFFLLSVFMNNRLLFDAFYVQET
SVYASLVFFFLLYSPIEFLLSIVLQMLSRKHEFEADYYAATTYSNGGALVDALKKLSRSSLSNLTPHPFYVFLNYSHPPV
LERIRRITNVTS

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=429, Percent_Identity=33.7995337995338, Blast_Score=218, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI17505484, Length=401, Percent_Identity=30.6733167082294, Blast_Score=174, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6322577, Length=416, Percent_Identity=36.0576923076923, Blast_Score=219, Evalue=5e-58,
Organism=Drosophila melanogaster, GI19922414, Length=408, Percent_Identity=29.4117647058824, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24654305, Length=411, Percent_Identity=23.1143552311436, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78707252, Length=397, Percent_Identity=23.1738035264484, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI78707254, Length=397, Percent_Identity=23.1738035264484, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 46336; Mature: 46336

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure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EEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]