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The map label for this gene is coaX [H]

Identifier: 194334325

GI number: 194334325

Start: 1659255

End: 1660037

Strand: Reverse

Name: coaX [H]

Synonym: Paes_1518

Alternate gene names: 194334325

Gene position: 1660037-1659255 (Counterclockwise)

Preceding gene: 194334326

Following gene: 194334322

Centisome position: 66.06

GC content: 50.83

Gene sequence:

>783_bases
ATGAGAGAAGCTCTTCTGATTATAGAGATCGGTAATTCAAGTACCGATATTGCGGTTTTTCAACAGGACCGCTGCTTAGA
ATGCCTACGGGTTCCGACTATATCGCTTGCCTCGCTGAGAGATATTGAATCTTCTCTTAACGAACTTCTTCAGCGTCATC
AGACGATTCGTGTCGCCGGAGTATGCAGCGTAGTGCCGAGATTGACCGATCTTTTCGCAGTTGCGCTCAAAGAGCTTTTT
TCAATGCGTATTGTCGGGATCGACAGCACTCTTGATCTTCCGTTTCGTTTCGAGTACAGCCCTCGGGAATCATTTGGCCC
GGATCGTATCGCTCTGTTGGCGATCAGTGCGGGGATCTACCCTCAAAAAGCAGTTATTGCTGTCGATATCGGGACCGCTA
TGACCTTTGATGTGCTTGACTCTTCACATCGCTATCGAGGCGGGATGATTCTTCCGGGGATTGATCTCATGGCATTTTCA
CTGCATGATCGTACAGCAAGGCTTCCTCTTGTCCGGATCTCTGACAGTGCGTCTCTCCTGGGGAGGTCAACAGAATCCTG
TATCCGGAGCGGGATCTACTGGGGGTGCATTAAGCAGGTTGACGGGATTCTGGGGGAGATACGCGATTTTCTTCAGACAG
AGACCGGTGATACCGACGTGGAGGTACTCATGACCGGCGGCAATTGCCGAATGGTCGCTTCAGGGCTTTCTGTTGCGGTG
ACGGTCGATGAGCATGCTGTACTCAAAGGTGCGGGAATGCTTGTCGGAATGAATTCCGCATGA

Upstream 100 bases:

>100_bases
CGTGACAAGGAATTTTCCTGGTTTCGACGATATTCTCAACGGTGTGTCTGCGCTCTCCGGTGTTCAGGTTGAAGGTCCCT
GAATGGAAAGGACGTTGTTT

Downstream 100 bases:

>100_bases
TCGCTTCAGCCGCTCCTTGCAGGTGACGAACCTTTTCAGCAGAACGTTTTTGCTTTTTCTATAGCGCCCGTAATCAGCTC
ATCGTCAAGTGTCTCGCGGT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MREALLIIEIGNSSTDIAVFQQDRCLECLRVPTISLASLRDIESSLNELLQRHQTIRVAGVCSVVPRLTDLFAVALKELF
SMRIVGIDSTLDLPFRFEYSPRESFGPDRIALLAISAGIYPQKAVIAVDIGTAMTFDVLDSSHRYRGGMILPGIDLMAFS
LHDRTARLPLVRISDSASLLGRSTESCIRSGIYWGCIKQVDGILGEIRDFLQTETGDTDVEVLMTGGNCRMVASGLSVAV
TVDEHAVLKGAGMLVGMNSA

Sequences:

>Translated_260_residues
MREALLIIEIGNSSTDIAVFQQDRCLECLRVPTISLASLRDIESSLNELLQRHQTIRVAGVCSVVPRLTDLFAVALKELF
SMRIVGIDSTLDLPFRFEYSPRESFGPDRIALLAISAGIYPQKAVIAVDIGTAMTFDVLDSSHRYRGGMILPGIDLMAFS
LHDRTARLPLVRISDSASLLGRSTESCIRSGIYWGCIKQVDGILGEIRDFLQTETGDTDVEVLMTGGNCRMVASGLSVAV
TVDEHAVLKGAGMLVGMNSA
>Mature_260_residues
MREALLIIEIGNSSTDIAVFQQDRCLECLRVPTISLASLRDIESSLNELLQRHQTIRVAGVCSVVPRLTDLFAVALKELF
SMRIVGIDSTLDLPFRFEYSPRESFGPDRIALLAISAGIYPQKAVIAVDIGTAMTFDVLDSSHRYRGGMILPGIDLMAFS
LHDRTARLPLVRISDSASLLGRSTESCIRSGIYWGCIKQVDGILGEIRDFLQTETGDTDVEVLMTGGNCRMVASGLSVAV
TVDEHAVLKGAGMLVGMNSA

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 28251; Mature: 28251

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREALLIIEIGNSSTDIAVFQQDRCLECLRVPTISLASLRDIESSLNELLQRHQTIRVAG
CCCEEEEEEECCCCCEEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEHH
VCSVVPRLTDLFAVALKELFSMRIVGIDSTLDLPFRFEYSPRESFGPDRIALLAISAGIY
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEECCCCCCCCCCEEEEEEEECCCC
PQKAVIAVDIGTAMTFDVLDSSHRYRGGMILPGIDLMAFSLHDRTARLPLVRISDSASLL
CCCEEEEEECCCEEEEEHHCCCCCCCCCEEECCHHEEEEEECCCCCCCCEEEECCCHHHH
GRSTESCIRSGIYWGCIKQVDGILGEIRDFLQTETGDTDVEVLMTGGNCRMVASGLSVAV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCEEEE
TVDEHAVLKGAGMLVGMNSA
EECCCCEEECCCEEEEECCC
>Mature Secondary Structure
MREALLIIEIGNSSTDIAVFQQDRCLECLRVPTISLASLRDIESSLNELLQRHQTIRVAG
CCCEEEEEEECCCCCEEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEHH
VCSVVPRLTDLFAVALKELFSMRIVGIDSTLDLPFRFEYSPRESFGPDRIALLAISAGIY
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEECCCCCCCCCCEEEEEEEECCCC
PQKAVIAVDIGTAMTFDVLDSSHRYRGGMILPGIDLMAFSLHDRTARLPLVRISDSASLL
CCCEEEEEECCCEEEEEHHCCCCCCCCCEEECCHHEEEEEECCCCCCCCEEEECCCHHHH
GRSTESCIRSGIYWGCIKQVDGILGEIRDFLQTETGDTDVEVLMTGGNCRMVASGLSVAV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCEEEE
TVDEHAVLKGAGMLVGMNSA
EECCCCEEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]