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The map label for this gene is tktB [C]

Identifier: 194334181

GI number: 194334181

Start: 1494814

End: 1495725

Strand: Reverse

Name: tktB [C]

Synonym: Paes_1373

Alternate gene names: 194334181

Gene position: 1495725-1494814 (Counterclockwise)

Preceding gene: 194334182

Following gene: 194334180

Centisome position: 59.52

GC content: 51.54

Gene sequence:

>912_bases
ATGGCAAAAGATTTAAAACCTTATCCTTCGGGACGGAAAGGTGAGATTATTTCTCTCGACACTGTTGATGAACTCAAGGA
GATGGCCTGCCAGGTTCGTCGAGATGTGGTCCGGATGCTGACTCGGGCGGCTTCAGGTCATACCGGAGGTTCTCTCGGCA
TGGCTGATGTTTTTACGGCATTATACTTCAGAATCATGCGCCATGATCCTCACGGTTTCTGGGAAAACCCGGATCAGGAT
ATGCTTTTTCTCTCCAACGGCCATATCGTACCTGTCTGGTACAGCGTTCTTGCGCGTTCAGGTTATTTTCCGACAGAAGA
ACTGGATTCTCTGCGCCAGATAGATAGCTACCTGCAGGGACACCCGACATCTGACGCCCGGCTTCCCGGGATCAGAATAG
CGTCAGGATCTCTTGGACAGGGGCTTTCTGCGGCGGTCGGTGCGGCCCTGGGGGTTAAAATGGACAATCGTGATGCAGAT
GTTTTCTGCCTGATGGGGGACGGTGAGTGTCAGGAAGGGCAGATATGGGAGGCGGCTATGAGTGCAACCCATTATGGTCT
CGACAATCTTATCGGCATTGTCGATTACAATAAGCTCCAGATCGATGGAGAGGTGTGTGACGTTATGTGCGTTGAGCCTT
TCGGCGACAAGTGGAAGGCTTTCGGATGGGATGTCTATCATTGTGACGGTAACGATATCGATGCCCTGGTCTCGACTGTT
GAAGAGATCCGATCGAGAGAACAGGCTGTCGGTCCGGCTGTCATTCTTGCTTCTACCGTTATGGGGAAAGGTGTTCCGTT
TTTCGAAGGTGTCATGCCCGATAAGTCCAACTGGCACGGCAAACCGCCTTCTGCGGATCATTGCGAGAAAGCTTTGGCGA
TTCTTGGTGAAACCTCTTTCGGCGATTATTGA

Upstream 100 bases:

>100_bases
AACAGGAGGTCTAATTTGTTGCAATTTTTCCCTGATGCCTGTACCTTTAGGGTTTAATTGGACGCCTTACTACTTCAAGA
AGCATTTACAGCATATAATC

Downstream 100 bases:

>100_bases
TCGCCGCGTTATAAGGTGCAGATTCAAACCGGCATATATAAAGGCCAGAAGCTTCTTCGCGCATCGAATCGCGCAATCCG
TCCCTGCAGCAGCAGGGTGA

Product: transketolase domain-containing protein

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MAKDLKPYPSGRKGEIISLDTVDELKEMACQVRRDVVRMLTRAASGHTGGSLGMADVFTALYFRIMRHDPHGFWENPDQD
MLFLSNGHIVPVWYSVLARSGYFPTEELDSLRQIDSYLQGHPTSDARLPGIRIASGSLGQGLSAAVGAALGVKMDNRDAD
VFCLMGDGECQEGQIWEAAMSATHYGLDNLIGIVDYNKLQIDGEVCDVMCVEPFGDKWKAFGWDVYHCDGNDIDALVSTV
EEIRSREQAVGPAVILASTVMGKGVPFFEGVMPDKSNWHGKPPSADHCEKALAILGETSFGDY

Sequences:

>Translated_303_residues
MAKDLKPYPSGRKGEIISLDTVDELKEMACQVRRDVVRMLTRAASGHTGGSLGMADVFTALYFRIMRHDPHGFWENPDQD
MLFLSNGHIVPVWYSVLARSGYFPTEELDSLRQIDSYLQGHPTSDARLPGIRIASGSLGQGLSAAVGAALGVKMDNRDAD
VFCLMGDGECQEGQIWEAAMSATHYGLDNLIGIVDYNKLQIDGEVCDVMCVEPFGDKWKAFGWDVYHCDGNDIDALVSTV
EEIRSREQAVGPAVILASTVMGKGVPFFEGVMPDKSNWHGKPPSADHCEKALAILGETSFGDY
>Mature_302_residues
AKDLKPYPSGRKGEIISLDTVDELKEMACQVRRDVVRMLTRAASGHTGGSLGMADVFTALYFRIMRHDPHGFWENPDQDM
LFLSNGHIVPVWYSVLARSGYFPTEELDSLRQIDSYLQGHPTSDARLPGIRIASGSLGQGLSAAVGAALGVKMDNRDADV
FCLMGDGECQEGQIWEAAMSATHYGLDNLIGIVDYNKLQIDGEVCDVMCVEPFGDKWKAFGWDVYHCDGNDIDALVSTVE
EIRSREQAVGPAVILASTVMGKGVPFFEGVMPDKSNWHGKPPSADHCEKALAILGETSFGDY

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=289, Percent_Identity=36.3321799307958, Blast_Score=174, Evalue=7e-44,
Organism=Homo sapiens, GI205277463, Length=272, Percent_Identity=35.2941176470588, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4507521, Length=272, Percent_Identity=35.2941176470588, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI225637459, Length=266, Percent_Identity=31.203007518797, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI225637461, Length=266, Percent_Identity=30.8270676691729, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI225637463, Length=228, Percent_Identity=32.4561403508772, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1788808, Length=286, Percent_Identity=33.5664335664336, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI48994911, Length=272, Percent_Identity=33.0882352941176, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17539652, Length=261, Percent_Identity=37.9310344827586, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6325331, Length=288, Percent_Identity=32.9861111111111, Blast_Score=122, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6319593, Length=253, Percent_Identity=32.8063241106719, Blast_Score=109, Evalue=5e-25,
Organism=Drosophila melanogaster, GI45551847, Length=263, Percent_Identity=34.9809885931559, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI45550715, Length=263, Percent_Identity=34.9809885931559, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24666278, Length=265, Percent_Identity=36.6037735849057, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24645119, Length=225, Percent_Identity=36.4444444444444, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 33141; Mature: 33010

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDLKPYPSGRKGEIISLDTVDELKEMACQVRRDVVRMLTRAASGHTGGSLGMADVFTA
CCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LYFRIMRHDPHGFWENPDQDMLFLSNGHIVPVWYSVLARSGYFPTEELDSLRQIDSYLQG
HHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
HPTSDARLPGIRIASGSLGQGLSAAVGAALGVKMDNRDADVFCLMGDGECQEGQIWEAAM
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHCEEECCCCCCEEEEECCCCCCCCHHHHHHH
SATHYGLDNLIGIVDYNKLQIDGEVCDVMCVEPFGDKWKAFGWDVYHCDGNDIDALVSTV
HHHHCCHHHHEEEEECCEEEECCCEEEEEEECCCCCCHHHCCCEEEEECCCCHHHHHHHH
EEIRSREQAVGPAVILASTVMGKGVPFFEGVMPDKSNWHGKPPSADHCEKALAILGETSF
HHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
GDY
CCC
>Mature Secondary Structure 
AKDLKPYPSGRKGEIISLDTVDELKEMACQVRRDVVRMLTRAASGHTGGSLGMADVFTA
CCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LYFRIMRHDPHGFWENPDQDMLFLSNGHIVPVWYSVLARSGYFPTEELDSLRQIDSYLQG
HHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
HPTSDARLPGIRIASGSLGQGLSAAVGAALGVKMDNRDADVFCLMGDGECQEGQIWEAAM
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHCEEECCCCCCEEEEECCCCCCCCHHHHHHH
SATHYGLDNLIGIVDYNKLQIDGEVCDVMCVEPFGDKWKAFGWDVYHCDGNDIDALVSTV
HHHHCCHHHHEEEEECCEEEECCCEEEEEEECCCCCCHHHCCCEEEEECCCCHHHHHHHH
EEIRSREQAVGPAVILASTVMGKGVPFFEGVMPDKSNWHGKPPSADHCEKALAILGETSF
HHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
GDY
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]