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The map label for this gene is coaD

Identifier: 194334179

GI number: 194334179

Start: 1493747

End: 1494253

Strand: Reverse

Name: coaD

Synonym: Paes_1371

Alternate gene names: 194334179

Gene position: 1494253-1493747 (Counterclockwise)

Preceding gene: 194334180

Following gene: 194334178

Centisome position: 59.46

GC content: 47.34

Gene sequence:

>507_bases
ATGACACAGATCGCCATTTATCCCGGGACGTTTGACCCATTTACTAACGGTCATCTTGACGTCTTCGAGCGGGCATCGAA
CATTTTTGATTCAGTCGTTGTTGTCATTGCTGAGAACAGTCGTAAAAATACGCTGTTCAGCGTTGACGAACGCCGTGAGA
TGATCGAAAAAATTATCGGCAGGTATCCCGGTGCGCGAGTGGAGGTTCTTCATGACGGGCTTCTTGCCGATTATGCTCGG
CAGGTTGGGGCAAAGGCGATTGTCAGAGGTGTTCGGCAGGTCAAGGATTTTGAGTATGAGTTTCAGATGTCGCTCCTCAA
TCGCCAGTTGAATCCTGACGTGACGACCGTTTTTCTTATGCCGAATGTGAAGTATACCTATGTGGCTTCATCGATTATCC
GCGAAGTGGCCATGCTTGGCGGCGATGTTCATAATTTCGTTCATCCGAATGTGCTCGAAAAGCTTCACGAGAAGTACAAT
GTTTGTAAGGGGCAATCAAATACATAA

Upstream 100 bases:

>100_bases
AGCACAGTGCCGAGCATGATTTGACGGGGATTGAGCAGTATGCTTTTCATAAGGATTATGGAATGACAAGGGTAACTTTT
TTTATGCTGGAGGAACAGCC

Downstream 100 bases:

>100_bases
ACCAACTACGCTGTTATGAGCGCAACTATTTCTCCAGAAGAAAAATATCTGACCCGGCGGGTATTGAATATGCAGGAGTC
CCAGACGATGCGGATTACCG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MTQIAIYPGTFDPFTNGHLDVFERASNIFDSVVVVIAENSRKNTLFSVDERREMIEKIIGRYPGARVEVLHDGLLADYAR
QVGAKAIVRGVRQVKDFEYEFQMSLLNRQLNPDVTTVFLMPNVKYTYVASSIIREVAMLGGDVHNFVHPNVLEKLHEKYN
VCKGQSNT

Sequences:

>Translated_168_residues
MTQIAIYPGTFDPFTNGHLDVFERASNIFDSVVVVIAENSRKNTLFSVDERREMIEKIIGRYPGARVEVLHDGLLADYAR
QVGAKAIVRGVRQVKDFEYEFQMSLLNRQLNPDVTTVFLMPNVKYTYVASSIIREVAMLGGDVHNFVHPNVLEKLHEKYN
VCKGQSNT
>Mature_167_residues
TQIAIYPGTFDPFTNGHLDVFERASNIFDSVVVVIAENSRKNTLFSVDERREMIEKIIGRYPGARVEVLHDGLLADYARQ
VGAKAIVRGVRQVKDFEYEFQMSLLNRQLNPDVTTVFLMPNVKYTYVASSIIREVAMLGGDVHNFVHPNVLEKLHEKYNV
CKGQSNT

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=41.1392405063291, Blast_Score=139, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_PROA2 (B4S8K5)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002016039.1
- ProteinModelPortal:   B4S8K5
- GeneID:   6460758
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_1371
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 19094; Mature: 18963

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQIAIYPGTFDPFTNGHLDVFERASNIFDSVVVVIAENSRKNTLFSVDERREMIEKIIG
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCEEEHHHHHHHHHHHHH
RYPGARVEVLHDGLLADYARQVGAKAIVRGVRQVKDFEYEFQMSLLNRQLNPDVTTVFLM
HCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
PNVKYTYVASSIIREVAMLGGDVHNFVHPNVLEKLHEKYNVCKGQSNT
CCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQIAIYPGTFDPFTNGHLDVFERASNIFDSVVVVIAENSRKNTLFSVDERREMIEKIIG
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCEEEHHHHHHHHHHHHH
RYPGARVEVLHDGLLADYARQVGAKAIVRGVRQVKDFEYEFQMSLLNRQLNPDVTTVFLM
HCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
PNVKYTYVASSIIREVAMLGGDVHNFVHPNVLEKLHEKYNVCKGQSNT
CCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA