Click here to switch to the map view.

The map label for this gene is aatA [H]

Identifier: 194334178

GI number: 194334178

Start: 1492523

End: 1493659

Strand: Reverse

Name: aatA [H]

Synonym: Paes_1370

Alternate gene names: 194334178

Gene position: 1493659-1492523 (Counterclockwise)

Preceding gene: 194334179

Following gene: 194334177

Centisome position: 59.44

GC content: 50.4

Gene sequence:

>1137_bases
ATGCGGATTACCGGGCTTGCCAAGAAAATGAAAGCTGAAGGCAAGGATATTGTCAGTCTGTCAGCCGGAGAGCCGGATTT
TCCGACTCCTCTTTTTGTGTCACAGGCGGGAATAGAGGCTATTGATTCTGGTTTTACCCGTTATACGGCCAATTCCGGCA
TTGCAGAGCTCAAGTCGGCCGTGATCGCAAAACTCAAAAGAGACAACCAGCTCGATTATACGCCTGACGAGGTGATTGTG
AGCAACGGCGGAAAGCAGACGCTTATCAACGCTATTCTTGCGTTATGCCAGGAGGGGGACGAGGTGATCATTCCTGCGCC
TTACTGGGTGAGTTTTCCTGAAATGGTGAGACTTGCCGGCGCTTCTCCGGTTACGGTTCCTACGTCGATCGAGAATGGTT
ACAAGATGACACCGGAGGATCTTGAGAACGCAATTACGGATAAGACCAAGCTCTTTATTCTCAATTCACCTTCCAATCCT
TCCGGTGCGGTCTACAACGAGCAGGAAGTCACAGCGCTTATGCAGGTGCTCGAAGGACGCGGAATTTTTGTGATTTCAGA
CGAGATGTATGATAAGATCGTCTATGGAGATGTCAAACCTTATTCTCCAGCCCGAATTGAGGCAATGCGTGACTGGGTGC
TCGTCAGCAACGGTGTTTCGAAAACCTACGCGATGACCGGTTGGAGGATTGGATATCTGGCTGGTCCAAAGTGGATTATC
AAGGCTTGCGACAAAATTCAGTCACAGACGACCTCAAACCCTAATTCGATTGCCCAGAAAGCGGCTGCGGCGGCTTTGAA
CGGTGATCAGCAGGTGGTAGAGGATCGCAGGTTGGAGTTTGAAAAACGGCGCGATTACATGTACAAAGCGCTCAACGAGA
TTCCCGGTATAACGGCGAGCCTGCCTGAGGGAGCCTTTTATATTTTCCCTTCGGTCAAGGGGGTTCTGGGTAAAACCTTT
AATGGCCGGTATCTTGCCAATTCAAGCGATGTGGCGGAGTATCTGCTTCTCGACCACTATGTGGCTACGGTTCCAGGAGA
TGCGTTCGGTGCACCTGAGAACCTCAGACTCTCCTATGCGGCTTCGATTTCAGAGCTTGAAGAGGCTGTACGCAGAATTC
GTAAAGCCTTTGAGTAG

Upstream 100 bases:

>100_bases
ATCAAATACATAAACCAACTACGCTGTTATGAGCGCAACTATTTCTCCAGAAGAAAAATATCTGACCCGGCGGGTATTGA
ATATGCAGGAGTCCCAGACG

Downstream 100 bases:

>100_bases
CGGGTTATGCTGACTGTTCGCCGAAGCAGGCTCTACACCCGTTGGTTCAGCTGGTATGCACGGCGGCAGTTCAGGCGCCA
TTTTCATTCGCTCAGGGTTG

Product: aminotransferase class I and II protein

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MRITGLAKKMKAEGKDIVSLSAGEPDFPTPLFVSQAGIEAIDSGFTRYTANSGIAELKSAVIAKLKRDNQLDYTPDEVIV
SNGGKQTLINAILALCQEGDEVIIPAPYWVSFPEMVRLAGASPVTVPTSIENGYKMTPEDLENAITDKTKLFILNSPSNP
SGAVYNEQEVTALMQVLEGRGIFVISDEMYDKIVYGDVKPYSPARIEAMRDWVLVSNGVSKTYAMTGWRIGYLAGPKWII
KACDKIQSQTTSNPNSIAQKAAAAALNGDQQVVEDRRLEFEKRRDYMYKALNEIPGITASLPEGAFYIFPSVKGVLGKTF
NGRYLANSSDVAEYLLLDHYVATVPGDAFGAPENLRLSYAASISELEEAVRRIRKAFE

Sequences:

>Translated_378_residues
MRITGLAKKMKAEGKDIVSLSAGEPDFPTPLFVSQAGIEAIDSGFTRYTANSGIAELKSAVIAKLKRDNQLDYTPDEVIV
SNGGKQTLINAILALCQEGDEVIIPAPYWVSFPEMVRLAGASPVTVPTSIENGYKMTPEDLENAITDKTKLFILNSPSNP
SGAVYNEQEVTALMQVLEGRGIFVISDEMYDKIVYGDVKPYSPARIEAMRDWVLVSNGVSKTYAMTGWRIGYLAGPKWII
KACDKIQSQTTSNPNSIAQKAAAAALNGDQQVVEDRRLEFEKRRDYMYKALNEIPGITASLPEGAFYIFPSVKGVLGKTF
NGRYLANSSDVAEYLLLDHYVATVPGDAFGAPENLRLSYAASISELEEAVRRIRKAFE
>Mature_378_residues
MRITGLAKKMKAEGKDIVSLSAGEPDFPTPLFVSQAGIEAIDSGFTRYTANSGIAELKSAVIAKLKRDNQLDYTPDEVIV
SNGGKQTLINAILALCQEGDEVIIPAPYWVSFPEMVRLAGASPVTVPTSIENGYKMTPEDLENAITDKTKLFILNSPSNP
SGAVYNEQEVTALMQVLEGRGIFVISDEMYDKIVYGDVKPYSPARIEAMRDWVLVSNGVSKTYAMTGWRIGYLAGPKWII
KACDKIQSQTTSNPNSIAQKAAAAALNGDQQVVEDRRLEFEKRRDYMYKALNEIPGITASLPEGAFYIFPSVKGVLGKTF
NGRYLANSSDVAEYLLLDHYVATVPGDAFGAPENLRLSYAASISELEEAVRRIRKAFE

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=316, Percent_Identity=31.3291139240506, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI56713256, Length=316, Percent_Identity=31.3291139240506, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI95147551, Length=344, Percent_Identity=27.0348837209302, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI169881279, Length=344, Percent_Identity=27.0348837209302, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4507369, Length=391, Percent_Identity=24.8081841432225, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI169881281, Length=341, Percent_Identity=22.8739002932551, Blast_Score=108, Evalue=7e-24,
Organism=Escherichia coli, GI1786816, Length=383, Percent_Identity=28.1984334203655, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788722, Length=381, Percent_Identity=29.1338582677165, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788627, Length=386, Percent_Identity=26.4248704663212, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787710, Length=336, Percent_Identity=22.9166666666667, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790797, Length=259, Percent_Identity=24.7104247104247, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788332, Length=242, Percent_Identity=25.2066115702479, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=386, Percent_Identity=25.3886010362694, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=281, Percent_Identity=26.6903914590747, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=281, Percent_Identity=26.6903914590747, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=396, Percent_Identity=22.979797979798, Blast_Score=101, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6322401, Length=392, Percent_Identity=23.9795918367347, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320317, Length=338, Percent_Identity=23.0769230769231, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=349, Percent_Identity=21.2034383954155, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573069, Length=331, Percent_Identity=23.8670694864048, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24646114, Length=331, Percent_Identity=23.8670694864048, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI28573067, Length=331, Percent_Identity=23.8670694864048, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI28573065, Length=331, Percent_Identity=23.8670694864048, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI18859735, Length=408, Percent_Identity=23.7745098039216, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 41390; Mature: 41390

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITGLAKKMKAEGKDIVSLSAGEPDFPTPLFVSQAGIEAIDSGFTRYTANSGIAELKSA
CCCHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCHHHHHHH
VIAKLKRDNQLDYTPDEVIVSNGGKQTLINAILALCQEGDEVIIPAPYWVSFPEMVRLAG
HHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHCC
ASPVTVPTSIENGYKMTPEDLENAITDKTKLFILNSPSNPSGAVYNEQEVTALMQVLEGR
CCCCEECCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCEECHHHHHHHHHHHCCC
GIFVISDEMYDKIVYGDVKPYSPARIEAMRDWVLVSNGVSKTYAMTGWRIGYLAGPKWII
CEEEECHHHHHHHEECCCCCCCCHHHHHHHHEEEEECCCCCCEEECCEEEEEECCHHHHH
KACDKIQSQTTSNPNSIAQKAAAAALNGDQQVVEDRRLEFEKRRDYMYKALNEIPGITAS
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LPEGAFYIFPSVKGVLGKTFNGRYLANSSDVAEYLLLDHYVATVPGDAFGAPENLRLSYA
CCCCEEEECCCHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHH
ASISELEEAVRRIRKAFE
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRITGLAKKMKAEGKDIVSLSAGEPDFPTPLFVSQAGIEAIDSGFTRYTANSGIAELKSA
CCCHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCHHHHHHH
VIAKLKRDNQLDYTPDEVIVSNGGKQTLINAILALCQEGDEVIIPAPYWVSFPEMVRLAG
HHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHCC
ASPVTVPTSIENGYKMTPEDLENAITDKTKLFILNSPSNPSGAVYNEQEVTALMQVLEGR
CCCCEECCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCEECHHHHHHHHHHHCCC
GIFVISDEMYDKIVYGDVKPYSPARIEAMRDWVLVSNGVSKTYAMTGWRIGYLAGPKWII
CEEEECHHHHHHHEECCCCCCCCHHHHHHHHEEEEECCCCCCEEECCEEEEEECCHHHHH
KACDKIQSQTTSNPNSIAQKAAAAALNGDQQVVEDRRLEFEKRRDYMYKALNEIPGITAS
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LPEGAFYIFPSVKGVLGKTFNGRYLANSSDVAEYLLLDHYVATVPGDAFGAPENLRLSYA
CCCCEEEECCCHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHH
ASISELEEAVRRIRKAFE
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]