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The map label for this gene is pgi [H]

Identifier: 194334148

GI number: 194334148

Start: 1460546

End: 1462192

Strand: Reverse

Name: pgi [H]

Synonym: Paes_1339

Alternate gene names: 194334148

Gene position: 1462192-1460546 (Counterclockwise)

Preceding gene: 194334149

Following gene: 194334146

Centisome position: 58.19

GC content: 54.46

Gene sequence:

>1647_bases
ATGAGTTTACAGCAATCACCGGCCTGGCGCGCTTTGGCATCGCACAAACAGACACTGGATTGTGTTCTGATGCGAGACCT
GTTTGCCGATGACCCCGAACGGTTCAGCAGGTTTTCCATCCGCTCAGGTGATCTGCTTCTCGATTATTCCAAGAACAGGG
TGACGTCCGAAACCATGGCCCTTCTTGCCGATCTGGCCCGGGAGGCCGGCGTGGAAGCCTGCCGCGACGAGATGTTTGCA
GGCAGCAAAATCAACTTCACTGAAAAAAGGGCCGTGCTGCATACCGCTTTGCGACAGCCTTGGGGCTTTCAGCTTCTGCT
GGAAGGCGGTCAGGAGGTCGGAAAGGATATTGCAGCAGTGCTCGGGCAGATGAAAGGGTTTACCGAGCAGATTCTCAGCG
GAAAGTGGAAAGGATACAGCGGCAAGGCTATTACCGATGTGGTCAATATCGGGATTGGTGGTTCGGACCTGGGGCCGTAT
ATGGTTACCGAAGCGCTCAGACCGTTTGCGCATGGCGCCGTCAAGGTGCATTTCGTGTCAAACATCGACGGGACGCACAT
CAGCGAGACCCTGAAGCGGGTCGATGAGGAGACGACTTTGTTTATTATAGCATCAAAGACCTTCACGACGCAGGAAACAC
TGACCAACGCCCATACCGCCAGATCGTGGTTTCTTGAGCGAGCCGTTGACGAATCGTTTATTGCGCGTCATTTTGCAGCC
GTTTCAACCAATAAGGAGGCCGTTCAGGCATTTGGTATCGATACCGGCAACATGTTCGGTTTCTGGGACTGGGTCGGCGG
ACGTTACTCGCTCTGGTCGTCTATCGGCCTTTCAATTGCCTTGTATCTGGGCTTTGATCGCTTTCTCGAACTGCTGGCAG
GAGCGCACTCGATGGATGAACATTTTCGTTCCGCTCCGCTTGACGCAAACATTCCGGTCGTGCTTGCGCTGCTGGGCATC
TGGTACAACAACTTTTTCGATTTCCCTTCTCATGCAGTCATTCCCTATGATCAGTATCTGCATCGGCTGCCGGCCTACCT
TCAGCAGCTCGATATGGAGAGTAACGGCAAGCGGGTCGATCGCGACGGCAATGTGGTCGATTATGCGACCGGTCCGGTCA
TCTGGGGCGAGCCGGGCACGAATTCACAGCATGCGTTTTTTCAGCTGATGCATCAGGGGACGTCATGTGTGCCGGCTGAT
TTCATTTTGCCTCTGAAGACGCAGAACCCGGCAGGGGAGCATCACGATATTCTCGCCGCGAACTGTTTTGCCCAGACTGA
AGCGCTCATGAAAGGCAAAACCGCAGCAGAGGCGCGAGCGGAACTCGGTTCGGCAGGAATGAGCGAAGAGGAGATCGACG
CACTCGTGCCGCACAAGGTTTTTCCCGGCAACCGCCCGACCAATACCCTGATTTTCAATGAGATCAATCCGTTCAATCTC
GGCGCTCTTATTGCGATGTATGAACACAAAGTGTTCGTGCAGGGCGTGATCTGGAGAATCAACTCATTTGACCAGTGGGG
GGTCGAGCTTGGCAAGCAGCTGGCAAAAGCCATACTGCCTGAACTTGGTTCCGCTGATGACGTCGCAACCCACGACGCTT
CAACTAACGCGCTCATCAATCTCTACCGCCGTAGCAGGAATGGCTGA

Upstream 100 bases:

>100_bases
TGTCCGTCAGGAGTGTGATGATGAAGGCTGTCGCCTCCTTCTGCGGATGATGCCTTATTAATGGTTCTTATTATCAATAA
CATTTCAGACCAATGTTTTT

Downstream 100 bases:

>100_bases
AGCAGTTCCTCCTACGTTGAGGAGTTGAGATTGCCGTAGGGGTCGGCCCCCGTGCCGACCCTTCTCTTTACGAATAGCGA
ATAACGGATTTCAGTCCACG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MSLQQSPAWRALASHKQTLDCVLMRDLFADDPERFSRFSIRSGDLLLDYSKNRVTSETMALLADLAREAGVEACRDEMFA
GSKINFTEKRAVLHTALRQPWGFQLLLEGGQEVGKDIAAVLGQMKGFTEQILSGKWKGYSGKAITDVVNIGIGGSDLGPY
MVTEALRPFAHGAVKVHFVSNIDGTHISETLKRVDEETTLFIIASKTFTTQETLTNAHTARSWFLERAVDESFIARHFAA
VSTNKEAVQAFGIDTGNMFGFWDWVGGRYSLWSSIGLSIALYLGFDRFLELLAGAHSMDEHFRSAPLDANIPVVLALLGI
WYNNFFDFPSHAVIPYDQYLHRLPAYLQQLDMESNGKRVDRDGNVVDYATGPVIWGEPGTNSQHAFFQLMHQGTSCVPAD
FILPLKTQNPAGEHHDILAANCFAQTEALMKGKTAAEARAELGSAGMSEEEIDALVPHKVFPGNRPTNTLIFNEINPFNL
GALIAMYEHKVFVQGVIWRINSFDQWGVELGKQLAKAILPELGSADDVATHDASTNALINLYRRSRNG

Sequences:

>Translated_548_residues
MSLQQSPAWRALASHKQTLDCVLMRDLFADDPERFSRFSIRSGDLLLDYSKNRVTSETMALLADLAREAGVEACRDEMFA
GSKINFTEKRAVLHTALRQPWGFQLLLEGGQEVGKDIAAVLGQMKGFTEQILSGKWKGYSGKAITDVVNIGIGGSDLGPY
MVTEALRPFAHGAVKVHFVSNIDGTHISETLKRVDEETTLFIIASKTFTTQETLTNAHTARSWFLERAVDESFIARHFAA
VSTNKEAVQAFGIDTGNMFGFWDWVGGRYSLWSSIGLSIALYLGFDRFLELLAGAHSMDEHFRSAPLDANIPVVLALLGI
WYNNFFDFPSHAVIPYDQYLHRLPAYLQQLDMESNGKRVDRDGNVVDYATGPVIWGEPGTNSQHAFFQLMHQGTSCVPAD
FILPLKTQNPAGEHHDILAANCFAQTEALMKGKTAAEARAELGSAGMSEEEIDALVPHKVFPGNRPTNTLIFNEINPFNL
GALIAMYEHKVFVQGVIWRINSFDQWGVELGKQLAKAILPELGSADDVATHDASTNALINLYRRSRNG
>Mature_547_residues
SLQQSPAWRALASHKQTLDCVLMRDLFADDPERFSRFSIRSGDLLLDYSKNRVTSETMALLADLAREAGVEACRDEMFAG
SKINFTEKRAVLHTALRQPWGFQLLLEGGQEVGKDIAAVLGQMKGFTEQILSGKWKGYSGKAITDVVNIGIGGSDLGPYM
VTEALRPFAHGAVKVHFVSNIDGTHISETLKRVDEETTLFIIASKTFTTQETLTNAHTARSWFLERAVDESFIARHFAAV
STNKEAVQAFGIDTGNMFGFWDWVGGRYSLWSSIGLSIALYLGFDRFLELLAGAHSMDEHFRSAPLDANIPVVLALLGIW
YNNFFDFPSHAVIPYDQYLHRLPAYLQQLDMESNGKRVDRDGNVVDYATGPVIWGEPGTNSQHAFFQLMHQGTSCVPADF
ILPLKTQNPAGEHHDILAANCFAQTEALMKGKTAAEARAELGSAGMSEEEIDALVPHKVFPGNRPTNTLIFNEINPFNLG
ALIAMYEHKVFVQGVIWRINSFDQWGVELGKQLAKAILPELGSADDVATHDASTNALINLYRRSRNG

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=555, Percent_Identity=58.9189189189189, Blast_Score=686, Evalue=0.0,
Organism=Homo sapiens, GI296080693, Length=555, Percent_Identity=55.1351351351351, Blast_Score=625, Evalue=1e-179,
Organism=Escherichia coli, GI1790457, Length=543, Percent_Identity=61.5101289134438, Blast_Score=698, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71996708, Length=553, Percent_Identity=59.3128390596745, Blast_Score=671, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71996703, Length=553, Percent_Identity=59.3128390596745, Blast_Score=670, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319673, Length=547, Percent_Identity=55.9414990859232, Blast_Score=604, Evalue=1e-173,
Organism=Drosophila melanogaster, GI24651916, Length=549, Percent_Identity=59.7449908925319, Blast_Score=682, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651914, Length=549, Percent_Identity=59.7449908925319, Blast_Score=682, Evalue=0.0,
Organism=Drosophila melanogaster, GI17737445, Length=549, Percent_Identity=59.7449908925319, Blast_Score=682, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 60649; Mature: 60518

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2 ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQQSPAWRALASHKQTLDCVLMRDLFADDPERFSRFSIRSGDLLLDYSKNRVTSETMA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEECCCCCCHHHHHH
LLADLAREAGVEACRDEMFAGSKINFTEKRAVLHTALRQPWGFQLLLEGGQEVGKDIAAV
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHH
LGQMKGFTEQILSGKWKGYSGKAITDVVNIGIGGSDLGPYMVTEALRPFAHGAVKVHFVS
HHHHCCHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEC
NIDGTHISETLKRVDEETTLFIIASKTFTTQETLTNAHTARSWFLERAVDESFIARHFAA
CCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSTNKEAVQAFGIDTGNMFGFWDWVGGRYSLWSSIGLSIALYLGFDRFLELLAGAHSMDE
HCCCHHHHHHHCCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
HFRSAPLDANIPVVLALLGIWYNNFFDFPSHAVIPYDQYLHRLPAYLQQLDMESNGKRVD
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEC
RDGNVVDYATGPVIWGEPGTNSQHAFFQLMHQGTSCVPADFILPLKTQNPAGEHHDILAA
CCCCEEEEECCCEEECCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCHHHH
NCFAQTEALMKGKTAAEARAELGSAGMSEEEIDALVPHKVFPGNRPTNTLIFNEINPFNL
HHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCH
GALIAMYEHKVFVQGVIWRINSFDQWGVELGKQLAKAILPELGSADDVATHDASTNALIN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
LYRRSRNG
HHHHCCCC
>Mature Secondary Structure 
SLQQSPAWRALASHKQTLDCVLMRDLFADDPERFSRFSIRSGDLLLDYSKNRVTSETMA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEECCCCCCHHHHHH
LLADLAREAGVEACRDEMFAGSKINFTEKRAVLHTALRQPWGFQLLLEGGQEVGKDIAAV
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHH
LGQMKGFTEQILSGKWKGYSGKAITDVVNIGIGGSDLGPYMVTEALRPFAHGAVKVHFVS
HHHHCCHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEC
NIDGTHISETLKRVDEETTLFIIASKTFTTQETLTNAHTARSWFLERAVDESFIARHFAA
CCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSTNKEAVQAFGIDTGNMFGFWDWVGGRYSLWSSIGLSIALYLGFDRFLELLAGAHSMDE
HCCCHHHHHHHCCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
HFRSAPLDANIPVVLALLGIWYNNFFDFPSHAVIPYDQYLHRLPAYLQQLDMESNGKRVD
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEC
RDGNVVDYATGPVIWGEPGTNSQHAFFQLMHQGTSCVPADFILPLKTQNPAGEHHDILAA
CCCCEEEEECCCEEECCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCHHHH
NCFAQTEALMKGKTAAEARAELGSAGMSEEEIDALVPHKVFPGNRPTNTLIFNEINPFNL
HHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCH
GALIAMYEHKVFVQGVIWRINSFDQWGVELGKQLAKAILPELGSADDVATHDASTNALIN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
LYRRSRNG
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA