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The map label for this gene is yhdH [H]

Identifier: 194334077

GI number: 194334077

Start: 1367096

End: 1368106

Strand: Reverse

Name: yhdH [H]

Synonym: Paes_1264

Alternate gene names: 194334077

Gene position: 1368106-1367096 (Counterclockwise)

Preceding gene: 194334078

Following gene: 194334075

Centisome position: 54.44

GC content: 54.1

Gene sequence:

>1011_bases
ATGCAACTGACTGAAATCGAAAAGACTGAATTCAGAGCGTTTGTCGTCGAGGAAAGGGACGATCGATATAGCGGTGAGCT
GCAGCGGCGGCGTGTCGCCGATCTGCCTTCCGGTGATCTTCTTGTCAGGGTCTTCTACTCCTCGCTGAATTACAAAGACG
CGCTTTCGGCAAGCGGTAACAGAGGTGTCACGAAAGCGTATCCGCATACGCCAGGCATCGATGCTGTGGGCATGGTCGAA
AAGTCGGGGAGCAACGATTTTCTTGAGGGCGATCCTGTGATCGTTACTGGCTTTGACCTGGGAATGAATACCCCCGGAGG
ATTCGGGCAATATATCCGGGTGCCGTCCCGGTGGGCACTCAGGCTTCCGGATGGTCTTTCGATGCAGGAGGCTATGGCTT
TCGGCACCGCCGGACTGACAGCAGCTCTTTCAGTGCTTCGCCTGACGGAAACACTCAAACCCGAGGATGGCCGGATTGCT
GTATCCGGTGCTACCGGCGGTGTTGGCGCACTTGCCGTTGCAATGCTTTCGAAACTTGGCTATTGCGTCTCGGCTATTTC
GGGCAAGGAGCAGGAACGGGATTTTCTTTTGAACCTTGGTGCTGCAGAAGTGCTTCCCCGTAAGGATTTTCAGGATGAGG
AGCGTCGTCCATTGCACAAGGGCGTGTTTGCCGGAGCGGTGGATACTGTGGGAGGCACGATCCTTGTCAACCTCCTGAAG
TCGATGCAGCCGATGGGCGTGGTTACCTGTTGTGGCAACGTCGCATCACCTGAACTTCATCTTACGGTCTATCCGTTCAT
TCTGCGAGGTGTATCGCTGATTGGCATCGACTCTCAGAACTGCCCGATCGCTCTCAGGAAAAATGTCTGGTGTAAGCTTG
CCGGCGAATGGAAGCCGGACTGTCTTATGAATCTCAGCAAGGAGATATCCATGAGCGATCTTCCGGATTCGATCGAACGG
ATGCTACAGGGAAAACTCAAGGGAAGGACTGTGGTAAACCTGAATGCTTGA

Upstream 100 bases:

>100_bases
AGCCCGTATGTGGCCGAGCCTTCATATGCTGATCAAAGAGCTGAAAGGATAGTTCCCCGATGTTGTATGACATTTTTCTG
AAATCTACAACCATGATGGT

Downstream 100 bases:

>100_bases
TCAGGGCTGTTGTGTTCAACAAAGCCATGAGCCTTATCGTTGCTGGTTCGCCATGTTGGCCCTTCAGCTATGGGATGGTT
TTATGCGTGACAAGTATTGA

Product: YhdH/YhfP family quinone oxidoreductase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MQLTEIEKTEFRAFVVEERDDRYSGELQRRRVADLPSGDLLVRVFYSSLNYKDALSASGNRGVTKAYPHTPGIDAVGMVE
KSGSNDFLEGDPVIVTGFDLGMNTPGGFGQYIRVPSRWALRLPDGLSMQEAMAFGTAGLTAALSVLRLTETLKPEDGRIA
VSGATGGVGALAVAMLSKLGYCVSAISGKEQERDFLLNLGAAEVLPRKDFQDEERRPLHKGVFAGAVDTVGGTILVNLLK
SMQPMGVVTCCGNVASPELHLTVYPFILRGVSLIGIDSQNCPIALRKNVWCKLAGEWKPDCLMNLSKEISMSDLPDSIER
MLQGKLKGRTVVNLNA

Sequences:

>Translated_336_residues
MQLTEIEKTEFRAFVVEERDDRYSGELQRRRVADLPSGDLLVRVFYSSLNYKDALSASGNRGVTKAYPHTPGIDAVGMVE
KSGSNDFLEGDPVIVTGFDLGMNTPGGFGQYIRVPSRWALRLPDGLSMQEAMAFGTAGLTAALSVLRLTETLKPEDGRIA
VSGATGGVGALAVAMLSKLGYCVSAISGKEQERDFLLNLGAAEVLPRKDFQDEERRPLHKGVFAGAVDTVGGTILVNLLK
SMQPMGVVTCCGNVASPELHLTVYPFILRGVSLIGIDSQNCPIALRKNVWCKLAGEWKPDCLMNLSKEISMSDLPDSIER
MLQGKLKGRTVVNLNA
>Mature_336_residues
MQLTEIEKTEFRAFVVEERDDRYSGELQRRRVADLPSGDLLVRVFYSSLNYKDALSASGNRGVTKAYPHTPGIDAVGMVE
KSGSNDFLEGDPVIVTGFDLGMNTPGGFGQYIRVPSRWALRLPDGLSMQEAMAFGTAGLTAALSVLRLTETLKPEDGRIA
VSGATGGVGALAVAMLSKLGYCVSAISGKEQERDFLLNLGAAEVLPRKDFQDEERRPLHKGVFAGAVDTVGGTILVNLLK
SMQPMGVVTCCGNVASPELHLTVYPFILRGVSLIGIDSQNCPIALRKNVWCKLAGEWKPDCLMNLSKEISMSDLPDSIER
MLQGKLKGRTVVNLNA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789651, Length=326, Percent_Identity=41.7177914110429, Blast_Score=252, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36325; Mature: 36325

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTEIEKTEFRAFVVEERDDRYSGELQRRRVADLPSGDLLVRVFYSSLNYKDALSASGN
CCCCCCCHHHEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHCCCCC
RGVTKAYPHTPGIDAVGMVEKSGSNDFLEGDPVIVTGFDLGMNTPGGFGQYIRVPSRWAL
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCEEE
RLPDGLSMQEAMAFGTAGLTAALSVLRLTETLKPEDGRIAVSGATGGVGALAVAMLSKLG
ECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHH
YCVSAISGKEQERDFLLNLGAAEVLPRKDFQDEERRPLHKGVFAGAVDTVGGTILVNLLK
HHHHHHCCCCHHHHHHEECCHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SMQPMGVVTCCGNVASPELHLTVYPFILRGVSLIGIDSQNCPIALRKNVWCKLAGEWKPD
HCCCCEEEEECCCCCCCEEEEEEHHHHHCCCEEEEECCCCCCEEEECCEEEEECCCCCCH
CLMNLSKEISMSDLPDSIERMLQGKLKGRTVVNLNA
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MQLTEIEKTEFRAFVVEERDDRYSGELQRRRVADLPSGDLLVRVFYSSLNYKDALSASGN
CCCCCCCHHHEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHCCCCC
RGVTKAYPHTPGIDAVGMVEKSGSNDFLEGDPVIVTGFDLGMNTPGGFGQYIRVPSRWAL
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCEEE
RLPDGLSMQEAMAFGTAGLTAALSVLRLTETLKPEDGRIAVSGATGGVGALAVAMLSKLG
ECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHH
YCVSAISGKEQERDFLLNLGAAEVLPRKDFQDEERRPLHKGVFAGAVDTVGGTILVNLLK
HHHHHHCCCCHHHHHHEECCHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SMQPMGVVTCCGNVASPELHLTVYPFILRGVSLIGIDSQNCPIALRKNVWCKLAGEWKPD
HCCCCEEEEECCCCCCCEEEEEEHHHHHCCCEEEEECCCCCCEEEECCEEEEECCCCCCH
CLMNLSKEISMSDLPDSIERMLQGKLKGRTVVNLNA
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1370469; 9278503 [H]