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The map label for this gene is adh1 [H]

Identifier: 194334059

GI number: 194334059

Start: 1349924

End: 1351105

Strand: Reverse

Name: adh1 [H]

Synonym: Paes_1246

Alternate gene names: 194334059

Gene position: 1351105-1349924 (Counterclockwise)

Preceding gene: 194334060

Following gene: 194334058

Centisome position: 53.77

GC content: 50.76

Gene sequence:

>1182_bases
ATGGACAATTCTGCATTTACTCTTCTTCGTCAGCCCAATGTTATTTTTGGTCCGGGAAAGGTTCGGCTTCTCCCGGATCT
TATTGCCGGTTACGGCAGAAATGTACTGGTCGTTACCGGTGTCAGCACTCTCGAGCAATCAGGAGTTCTTGGAAAACTTT
TTGAGCAGCTACATTCCCGCTCTCTGCAGTATGGTCATCTGACGGTCTCACGGGAGCCTCATCCTGAACTCGTCGACCGT
GCTGTCAGCCGCTACAGGGAGAGCGGGATTGATGTTGTTGTTGCTATCGGAGGAGGGAGCGTTATTGATGCCGGCAAATC
GGTTTCTGCAATGCTGCTGAAATCAGATTCGATCGAACGATATATCGAAGGGCTGGATGGTTGTATTCAGCATGATGGTC
GTAAGGTGCCGTTTATCGCGCTTCCGACAACTTCGGGTACGGGAAGCGAAGCGACAAATAACGCTGTTATCAGTAAGGTT
GGAGTCGATGGGTACAAGCGTTCTCTTCGCCACCCTGAATTCGTTCCGGAGATTGCGCTTGTCGATCCGGAACTTATGCT
TGGCGCGCCTGCAGGTCTGACTGCCGCATCCGGCATGGATGCAGGAACACAACTTATAGAGGCTTTTGTTTCTCCGGGTT
CCTGCCGGTTTACCGATGTTGTCGCATGGAGCGGTCTTGAACATTTCAATCGTTCGTTTCTTCGGGCCTGCACTGATGGA
GCCGGAGATATTGAGGTCAGATCCGCTATGGCATATGCGGCGTTGATGTCGGGAATTGCTCTTGCAAACGCAGGGCTTGG
GATCGTTCACGGATTTGCATCTTCGGTTGGCGGATACTGCGATATAGCTCATGGTGTTCTTTGCGCGACTCTTCTCGCCT
CAGCCACAAAAGAAAATATTCTGCAATTACGCCAGACGGGGGATAACCCTGAAGCGCTCACTAAATATGCGGCAATTGGC
AGATTGTTCTCCGGTTGCGAAAATCTGTCGCAGGATGGAGCTTGTGATGCGCTGGTTGATACGTTGCTGAGTTGGCAGGA
GCAGCTTGATTTTCCTCGTCTTTCTTCTTATGGATTGAGATCCAGTGACCTTGAATCCATCGCCAGTCGGACACGAAGCA
AAAACAATGCAGTGGAGCTGCATCGCGATCAGTATATGAGCATATTGCGAGCACGCTTATAG

Upstream 100 bases:

>100_bases
CGGCAGCAAAAGTGGTTGCGCCCTTTGGCGCAGTTTCGCTCATTTCAGGCATTCTTGTCATGGTGCCCATTCTGGCCAAA
GGCGTAGACACTGAAAATTA

Downstream 100 bases:

>100_bases
GGAGTTTGAATAATTACTTGAAAAAGGCGTTTTTATTACGTTTTCTGATAGCCTTTTTTATTTTAAACCCCATACTGCTA
TGCGTTATTCCTTTTTTTGT

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: BDH [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MDNSAFTLLRQPNVIFGPGKVRLLPDLIAGYGRNVLVVTGVSTLEQSGVLGKLFEQLHSRSLQYGHLTVSREPHPELVDR
AVSRYRESGIDVVVAIGGGSVIDAGKSVSAMLLKSDSIERYIEGLDGCIQHDGRKVPFIALPTTSGTGSEATNNAVISKV
GVDGYKRSLRHPEFVPEIALVDPELMLGAPAGLTAASGMDAGTQLIEAFVSPGSCRFTDVVAWSGLEHFNRSFLRACTDG
AGDIEVRSAMAYAALMSGIALANAGLGIVHGFASSVGGYCDIAHGVLCATLLASATKENILQLRQTGDNPEALTKYAAIG
RLFSGCENLSQDGACDALVDTLLSWQEQLDFPRLSSYGLRSSDLESIASRTRSKNNAVELHRDQYMSILRARL

Sequences:

>Translated_393_residues
MDNSAFTLLRQPNVIFGPGKVRLLPDLIAGYGRNVLVVTGVSTLEQSGVLGKLFEQLHSRSLQYGHLTVSREPHPELVDR
AVSRYRESGIDVVVAIGGGSVIDAGKSVSAMLLKSDSIERYIEGLDGCIQHDGRKVPFIALPTTSGTGSEATNNAVISKV
GVDGYKRSLRHPEFVPEIALVDPELMLGAPAGLTAASGMDAGTQLIEAFVSPGSCRFTDVVAWSGLEHFNRSFLRACTDG
AGDIEVRSAMAYAALMSGIALANAGLGIVHGFASSVGGYCDIAHGVLCATLLASATKENILQLRQTGDNPEALTKYAAIG
RLFSGCENLSQDGACDALVDTLLSWQEQLDFPRLSSYGLRSSDLESIASRTRSKNNAVELHRDQYMSILRARL
>Mature_393_residues
MDNSAFTLLRQPNVIFGPGKVRLLPDLIAGYGRNVLVVTGVSTLEQSGVLGKLFEQLHSRSLQYGHLTVSREPHPELVDR
AVSRYRESGIDVVVAIGGGSVIDAGKSVSAMLLKSDSIERYIEGLDGCIQHDGRKVPFIALPTTSGTGSEATNNAVISKV
GVDGYKRSLRHPEFVPEIALVDPELMLGAPAGLTAASGMDAGTQLIEAFVSPGSCRFTDVVAWSGLEHFNRSFLRACTDG
AGDIEVRSAMAYAALMSGIALANAGLGIVHGFASSVGGYCDIAHGVLCATLLASATKENILQLRQTGDNPEALTKYAAIG
RLFSGCENLSQDGACDALVDTLLSWQEQLDFPRLSSYGLRSSDLESIASRTRSKNNAVELHRDQYMSILRARL

Specific function: This enzyme has activity using butanol and ethanol as substrates [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87082107, Length=316, Percent_Identity=33.8607594936709, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1789163, Length=360, Percent_Identity=29.7222222222222, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI48994951, Length=379, Percent_Identity=27.7044854881267, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787493, Length=326, Percent_Identity=30.0613496932515, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789386, Length=380, Percent_Identity=26.8421052631579, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17537053, Length=226, Percent_Identity=28.3185840707965, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321181, Length=389, Percent_Identity=29.8200514138817, Blast_Score=149, Evalue=9e-37,
Organism=Drosophila melanogaster, GI24657991, Length=291, Percent_Identity=28.5223367697594, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: NA

Molecular weight: Translated: 41856; Mature: 41856

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNSAFTLLRQPNVIFGPGKVRLLPDLIAGYGRNVLVVTGVSTLEQSGVLGKLFEQLHSR
CCCCEEEEEECCCEEECCCCEEECHHHHHHCCCCEEEEECHHHHHHCCHHHHHHHHHHHC
SLQYGHLTVSREPHPELVDRAVSRYRESGIDVVVAIGGGSVIDAGKSVSAMLLKSDSIER
CCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEECCCCCHHHHHHHHHHHHH
YIEGLDGCIQHDGRKVPFIALPTTSGTGSEATNNAVISKVGVDGYKRSLRHPEFVPEIAL
HHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCEE
VDPELMLGAPAGLTAASGMDAGTQLIEAFVSPGSCRFTDVVAWSGLEHFNRSFLRACTDG
ECCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHCCHHHHHHHHHHHHCCC
AGDIEVRSAMAYAALMSGIALANAGLGIVHGFASSVGGYCDIAHGVLCATLLASATKENI
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LQLRQTGDNPEALTKYAAIGRLFSGCENLSQDGACDALVDTLLSWQEQLDFPRLSSYGLR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCC
SSDLESIASRTRSKNNAVELHRDQYMSILRARL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDNSAFTLLRQPNVIFGPGKVRLLPDLIAGYGRNVLVVTGVSTLEQSGVLGKLFEQLHSR
CCCCEEEEEECCCEEECCCCEEECHHHHHHCCCCEEEEECHHHHHHCCHHHHHHHHHHHC
SLQYGHLTVSREPHPELVDRAVSRYRESGIDVVVAIGGGSVIDAGKSVSAMLLKSDSIER
CCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEECCCCCHHHHHHHHHHHHH
YIEGLDGCIQHDGRKVPFIALPTTSGTGSEATNNAVISKVGVDGYKRSLRHPEFVPEIAL
HHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCEE
VDPELMLGAPAGLTAASGMDAGTQLIEAFVSPGSCRFTDVVAWSGLEHFNRSFLRACTDG
ECCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHCCHHHHHHHHHHHHCCC
AGDIEVRSAMAYAALMSGIALANAGLGIVHGFASSVGGYCDIAHGVLCATLLASATKENI
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LQLRQTGDNPEALTKYAAIGRLFSGCENLSQDGACDALVDTLLSWQEQLDFPRLSSYGLR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCC
SSDLESIASRTRSKNNAVELHRDQYMSILRARL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2673928 [H]