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The map label for this gene is coaE [H]

Identifier: 194334009

GI number: 194334009

Start: 1300583

End: 1301209

Strand: Reverse

Name: coaE [H]

Synonym: Paes_1193

Alternate gene names: 194334009

Gene position: 1301209-1300583 (Counterclockwise)

Preceding gene: 194334010

Following gene: 194334005

Centisome position: 51.78

GC content: 53.11

Gene sequence:

>627_bases
ATGAATAACCGCCCTTTGCTTGTTGGCGTGACCGGCGGACTTGGCAGCGGCAAGAGCACTGTCTGCAGGATTCTTGCAGA
ATATGGCTGTGAGATTTTTGAGGCAGATAGCGTTGCCAGGCAGCTTCAGGTAACCGATCCGGTAATTATCGAGGGGATTC
GGCGTCTTTTCGGCAATGAGGTCTATCAGATGCGTGCCGATGGAGTCCTCTGGCTTGATCGTCCGGCGATTGCCCGCAGG
GTATTTGCCGATGCGAGCCTGCTTCAGAAGCTGAACCGGTTGATCCATCCTGCAGTTTACAGCGTTTTTCAGTCTGCTGT
CGATGATGCCCGTCGAAAAGGCATCAACGTTCTTGTCAAGGAAGCCGCTATATTGTTTGAGTCTGGGGGCGATACACTTC
TTGACTGTATCGTCGTCGTGACGGCCGACAGGGAATTGAGGATTCAGCGTGCCCTGCAAAGAGGCGGCGCTTCCCGGGAA
GATATTATCCGCCGTATCAATGCCCAGTGGCCTCAGGAAGAACTTGTCAGGCGTGCAGACTACGTTATCGACAACAGCGG
AACATTTGATCAGCTCAAAAGCCGAACGCGTCAGGTCTATGAATTGATCGTCAGGGATGCTCTCTGA

Upstream 100 bases:

>100_bases
ATCAGCTTACCCGTCGTTACCAGAATGATCCGCTTTTGTGGAAAAATGTGCTTCAGCAAGTCAGGCGCAATCTCGAACAG
AAGAGCAGTGGAGAGGGGCG

Downstream 100 bases:

>100_bases
TAGCGTTGGCGATCATGGGTAGTGAGACACTGTAGCGATAGGATGTGTCAGCGTGGGTGTCGGGAAATTCCTGATAGATG
TGTTTGATGCCGAGTTCTTT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MNNRPLLVGVTGGLGSGKSTVCRILAEYGCEIFEADSVARQLQVTDPVIIEGIRRLFGNEVYQMRADGVLWLDRPAIARR
VFADASLLQKLNRLIHPAVYSVFQSAVDDARRKGINVLVKEAAILFESGGDTLLDCIVVVTADRELRIQRALQRGGASRE
DIIRRINAQWPQEELVRRADYVIDNSGTFDQLKSRTRQVYELIVRDAL

Sequences:

>Translated_208_residues
MNNRPLLVGVTGGLGSGKSTVCRILAEYGCEIFEADSVARQLQVTDPVIIEGIRRLFGNEVYQMRADGVLWLDRPAIARR
VFADASLLQKLNRLIHPAVYSVFQSAVDDARRKGINVLVKEAAILFESGGDTLLDCIVVVTADRELRIQRALQRGGASRE
DIIRRINAQWPQEELVRRADYVIDNSGTFDQLKSRTRQVYELIVRDAL
>Mature_208_residues
MNNRPLLVGVTGGLGSGKSTVCRILAEYGCEIFEADSVARQLQVTDPVIIEGIRRLFGNEVYQMRADGVLWLDRPAIARR
VFADASLLQKLNRLIHPAVYSVFQSAVDDARRKGINVLVKEAAILFESGGDTLLDCIVVVTADRELRIQRALQRGGASRE
DIIRRINAQWPQEELVRRADYVIDNSGTFDQLKSRTRQVYELIVRDAL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=195, Percent_Identity=30.2564102564103, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI191252795, Length=195, Percent_Identity=30.2564102564103, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1786292, Length=194, Percent_Identity=30.9278350515464, Blast_Score=80, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17554944, Length=195, Percent_Identity=34.3589743589744, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320402, Length=211, Percent_Identity=32.2274881516588, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644728, Length=205, Percent_Identity=28.780487804878, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24658602, Length=208, Percent_Identity=24.0384615384615, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23324; Mature: 23324

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNRPLLVGVTGGLGSGKSTVCRILAEYGCEIFEADSVARQLQVTDPVIIEGIRRLFGNE
CCCCCEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHH
VYQMRADGVLWLDRPAIARRVFADASLLQKLNRLIHPAVYSVFQSAVDDARRKGINVLVK
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EAAILFESGGDTLLDCIVVVTADRELRIQRALQRGGASREDIIRRINAQWPQEELVRRAD
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHH
YVIDNSGTFDQLKSRTRQVYELIVRDAL
HHCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNRPLLVGVTGGLGSGKSTVCRILAEYGCEIFEADSVARQLQVTDPVIIEGIRRLFGNE
CCCCCEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHH
VYQMRADGVLWLDRPAIARRVFADASLLQKLNRLIHPAVYSVFQSAVDDARRKGINVLVK
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EAAILFESGGDTLLDCIVVVTADRELRIQRALQRGGASREDIIRRINAQWPQEELVRRAD
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHH
YVIDNSGTFDQLKSRTRQVYELIVRDAL
HHCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA