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The map label for this gene is 194333743

Identifier: 194333743

GI number: 194333743

Start: 1002124

End: 1003674

Strand: Reverse

Name: 194333743

Synonym: Paes_0913

Alternate gene names: NA

Gene position: 1003674-1002124 (Counterclockwise)

Preceding gene: 194333748

Following gene: 194333738

Centisome position: 39.94

GC content: 49.52

Gene sequence:

>1551_bases
ATGCTCTTCACCGCATTGCAGAACCCCGGGTCCTACCCGCATGATGTAGCGTCGGTCACCGTCGTTGAAACGCATATTTC
CATGGTGTTTCTGACAGGAACCTATGCCTACAAAGTCAAAAAACCGGTTGATCTCGGATTTCTTGACTTTTCGACTCTTG
AAAAAAGAAAGCAGTTCTGCCTTGAAGAGCTGAGGCTCAACAGAAGGCTCTGCCCTGACCTCTATCTCGACGTGCTACCC
ATCACTGAAGACAATGGACTGATAACGGTAGGCGGCAAAGGAAACGTTCTGGAATATGCGGTTCAGATGCTGGAGTTCGA
CCGGACAATGGAGCTTGATCTGCTCCTGAAAGAACATCGACTCACACCCGCTCATATTGACATGATCAGTGCGATTGTTT
CCGGCTTTCATCAGGCACTTTCGCCTTCCCCCCCAGGTTCCCCCTACGCAACTCCGGCACTGATCCTGCAAACCGTCCTC
AACAACTTTTCAAGGATAGAGACTGGCAACTGTTCGGATGATGAATCAGAAAGACTCGAGAAGCTGAAAGTGTGGACCGT
CAGAGCTCATGAACAATGCTCTTTACTCTTTGAAAAACGCAAACGCGAAGGGCTTGTCCGTCAATGTCATGGAGACATGC
ATAGCGGCAATATGGTCCTGAGAAACGGCGGTATCTGTATTTTTGACTGTATTGAGTTCAATCCGGAACTCAGCGTTATT
GACCTGTTCAGCGAAATAGCATTTTTTATCATGGACCTGGAGCACCGTTGCCACCCTGAACTGGCCTGGAGATTTCTCAA
CGCCTATCTCTCTGCCACAGGAGATTACGACGGGCTGAAGGTGCTTCGGTTCTATGCGGTATACAGAGCAATGGTGCGAG
CCAAGGTAACCTCGATACGCCTCCTGCAGGAAAACGATGCCCGCGATAAAACATTGACACATCAGGAGCATCTCTCGTTT
ATCTCGCTCGCCGAAAACTACACAACACTCCGCAAACCGGTTCTGATACTGACCAGAGGAGTCTCGGGAAGCGGAAAAAC
AACCCTCGCAGCCGAACTCTCCTCATTGATCCCCGCAGTTCACTGCCGCTCGGATGTCGAGCGCAAACGACTCTTTGGAC
TGAGCGCAAATGAGAAAAGCCGGGATGAAGATAAAAAAACAATCTACGCTGAAGCTTCGACCCGCCAAACCTATGCCCGG
CTGCTCAATATCGCAGAAACCTGCATCAACGAGCACTACAGTGTCATTGTTGATGCGACATTCATGACCGCAAACCAGAG
AGAACCGTTTTTACGCATCGCCAGGGAAAAAAAGTGCCCCACTGTTATCCTTGAGTGCAGCGCCCCGCTGCAGACCCTTG
AAAAACGGGTTATAAACCGACTCAGTAAAGCTTCCGATGCGTCAGAAGCCGGCATAGAGATCCTTTATCGGCAGATGGAA
AAACAGGACAGCCTCTCCCTGCAGGAAGAAGCTGTTGCCATAAAAGTCAATACGACAAAAAAAAATGCAACCGAAAGTAC
GCTCAGAATGATCCGGGAAAAAATTTCCTGA

Upstream 100 bases:

>100_bases
GGCGTCAAGAAACCGACAGCAGAAGAGAATTCATCAATTTTTCATAGCTTTCAGAAAAGCACTTGTCAAAGCGCTCTAAA
CGTTATCAACCAGATCATAG

Downstream 100 bases:

>100_bases
TCATACCTCAATGCCAAAAACAGCTCGAGCTGCCATCCCCGCCAGAAAACTCAGCAATGCGACCCCGAAACTCAAGCCGA
CCATTTCGAAAAACCTCGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MLFTALQNPGSYPHDVASVTVVETHISMVFLTGTYAYKVKKPVDLGFLDFSTLEKRKQFCLEELRLNRRLCPDLYLDVLP
ITEDNGLITVGGKGNVLEYAVQMLEFDRTMELDLLLKEHRLTPAHIDMISAIVSGFHQALSPSPPGSPYATPALILQTVL
NNFSRIETGNCSDDESERLEKLKVWTVRAHEQCSLLFEKRKREGLVRQCHGDMHSGNMVLRNGGICIFDCIEFNPELSVI
DLFSEIAFFIMDLEHRCHPELAWRFLNAYLSATGDYDGLKVLRFYAVYRAMVRAKVTSIRLLQENDARDKTLTHQEHLSF
ISLAENYTTLRKPVLILTRGVSGSGKTTLAAELSSLIPAVHCRSDVERKRLFGLSANEKSRDEDKKTIYAEASTRQTYAR
LLNIAETCINEHYSVIVDATFMTANQREPFLRIAREKKCPTVILECSAPLQTLEKRVINRLSKASDASEAGIEILYRQME
KQDSLSLQEEAVAIKVNTTKKNATESTLRMIREKIS

Sequences:

>Translated_516_residues
MLFTALQNPGSYPHDVASVTVVETHISMVFLTGTYAYKVKKPVDLGFLDFSTLEKRKQFCLEELRLNRRLCPDLYLDVLP
ITEDNGLITVGGKGNVLEYAVQMLEFDRTMELDLLLKEHRLTPAHIDMISAIVSGFHQALSPSPPGSPYATPALILQTVL
NNFSRIETGNCSDDESERLEKLKVWTVRAHEQCSLLFEKRKREGLVRQCHGDMHSGNMVLRNGGICIFDCIEFNPELSVI
DLFSEIAFFIMDLEHRCHPELAWRFLNAYLSATGDYDGLKVLRFYAVYRAMVRAKVTSIRLLQENDARDKTLTHQEHLSF
ISLAENYTTLRKPVLILTRGVSGSGKTTLAAELSSLIPAVHCRSDVERKRLFGLSANEKSRDEDKKTIYAEASTRQTYAR
LLNIAETCINEHYSVIVDATFMTANQREPFLRIAREKKCPTVILECSAPLQTLEKRVINRLSKASDASEAGIEILYRQME
KQDSLSLQEEAVAIKVNTTKKNATESTLRMIREKIS
>Mature_516_residues
MLFTALQNPGSYPHDVASVTVVETHISMVFLTGTYAYKVKKPVDLGFLDFSTLEKRKQFCLEELRLNRRLCPDLYLDVLP
ITEDNGLITVGGKGNVLEYAVQMLEFDRTMELDLLLKEHRLTPAHIDMISAIVSGFHQALSPSPPGSPYATPALILQTVL
NNFSRIETGNCSDDESERLEKLKVWTVRAHEQCSLLFEKRKREGLVRQCHGDMHSGNMVLRNGGICIFDCIEFNPELSVI
DLFSEIAFFIMDLEHRCHPELAWRFLNAYLSATGDYDGLKVLRFYAVYRAMVRAKVTSIRLLQENDARDKTLTHQEHLSF
ISLAENYTTLRKPVLILTRGVSGSGKTTLAAELSSLIPAVHCRSDVERKRLFGLSANEKSRDEDKKTIYAEASTRQTYAR
LLNIAETCINEHYSVIVDATFMTANQREPFLRIAREKKCPTVILECSAPLQTLEKRVINRLSKASDASEAGIEILYRQME
KQDSLSLQEEAVAIKVNTTKKNATESTLRMIREKIS

Specific function: Some isolated peptides of this protein are able to bind to human U937 monocytoblastic and A549 epithelial cell lines [H]

COG id: COG2187

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR010488 [H]

Pfam domain/function: PF06414 Zeta_toxin [H]

EC number: NA

Molecular weight: Translated: 58448; Mature: 58448

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFTALQNPGSYPHDVASVTVVETHISMVFLTGTYAYKVKKPVDLGFLDFSTLEKRKQFC
CEEEECCCCCCCCCCHHEEEEEEEEEEEEEEECEEEEEECCCCCCCCCCHHHHHHHHHHH
LEELRLNRRLCPDLYLDVLPITEDNGLITVGGKGNVLEYAVQMLEFDRTMELDLLLKEHR
HHHHHHHHCCCCHHHEEEEEEECCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHC
LTPAHIDMISAIVSGFHQALSPSPPGSPYATPALILQTVLNNFSRIETGNCSDDESERLE
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
KLKVWTVRAHEQCSLLFEKRKREGLVRQCHGDMHSGNMVLRNGGICIFDCIEFNPELSVI
HHHEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEECCCCCCHHH
DLFSEIAFFIMDLEHRCHPELAWRFLNAYLSATGDYDGLKVLRFYAVYRAMVRAKVTSIR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHE
LLQENDARDKTLTHQEHLSFISLAENYTTLRKPVLILTRGVSGSGKTTLAAELSSLIPAV
EEECCCCCCHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHH
HCRSDVERKRLFGLSANEKSRDEDKKTIYAEASTRQTYARLLNIAETCINEHYSVIVDAT
HHHHHHHHHHHCCCCCCCCCCCCCHHEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEE
FMTANQREPFLRIAREKKCPTVILECSAPLQTLEKRVINRLSKASDASEAGIEILYRQME
EEECCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KQDSLSLQEEAVAIKVNTTKKNATESTLRMIREKIS
HHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLFTALQNPGSYPHDVASVTVVETHISMVFLTGTYAYKVKKPVDLGFLDFSTLEKRKQFC
CEEEECCCCCCCCCCHHEEEEEEEEEEEEEEECEEEEEECCCCCCCCCCHHHHHHHHHHH
LEELRLNRRLCPDLYLDVLPITEDNGLITVGGKGNVLEYAVQMLEFDRTMELDLLLKEHR
HHHHHHHHCCCCHHHEEEEEEECCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHC
LTPAHIDMISAIVSGFHQALSPSPPGSPYATPALILQTVLNNFSRIETGNCSDDESERLE
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
KLKVWTVRAHEQCSLLFEKRKREGLVRQCHGDMHSGNMVLRNGGICIFDCIEFNPELSVI
HHHEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEECCCCCCHHH
DLFSEIAFFIMDLEHRCHPELAWRFLNAYLSATGDYDGLKVLRFYAVYRAMVRAKVTSIR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHE
LLQENDARDKTLTHQEHLSFISLAENYTTLRKPVLILTRGVSGSGKTTLAAELSSLIPAV
EEECCCCCCHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHH
HCRSDVERKRLFGLSANEKSRDEDKKTIYAEASTRQTYARLLNIAETCINEHYSVIVDAT
HHHHHHHHHHHCCCCCCCCCCCCCHHEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEE
FMTANQREPFLRIAREKKCPTVILECSAPLQTLEKRVINRLSKASDASEAGIEILYRQME
EEECCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KQDSLSLQEEAVAIKVNTTKKNATESTLRMIREKIS
HHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]