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The map label for this gene is ybaL [H]

Identifier: 194333668

GI number: 194333668

Start: 918007

End: 919692

Strand: Reverse

Name: ybaL [H]

Synonym: Paes_0835

Alternate gene names: 194333668

Gene position: 919692-918007 (Counterclockwise)

Preceding gene: 194333669

Following gene: 194333667

Centisome position: 36.6

GC content: 51.48

Gene sequence:

>1686_bases
ATGTTTGACCTTTCATTCATCCATACCGTCCCGTTTTACGAGATCACGGCACTCCTTGTGCTTGCCGCGATAACAGGCAG
TCTGAGCCTCCTGCTCCGCCAACCGTTGATCGTCAGTCTCATCGCCGTCGGAGTCCTTGCCGGACCATCTGCACTCGATA
TCGTTCAGTCGCATGAATACATCGAGCTGATGGCCGAACTCGGCATAGCCCTCCTGCTTTTTCTCGTCGGATTGAAGCTC
GATATCTCTCTTGTCAGATCGCTCGGTCTTGTTGCACTGGCAACCGGTCTCGGACAGGTACTGTTTACATCGGTCACTGG
ATTTTTCATTGCGCAGGCTCTTGGTCTTGATGTCCGGACCTCAATCTATGTTGCCGTAGCACTGACCTTCTCAAGTACCA
TCATCATTGTAAAACTGCTTTCAGATAAAAAGGAGGTTGACTCACTCCACGGTCGCGTCGCGCTGGGATTCCTTATCGTA
CAGGACCTCGTCGTGGTTATCGCCATGATGACCCTGTCAGCTTTCGCTGTCAGTAGCCAAAGCACGGGAGAATACGACGG
TCTGCTTCAAGTCGGATCGGTCATAGTCTACGGCGGGCTCATGCTGCTGCTTGTCAGCATCTTTGTCAGGTTTCTGGCAA
ATCCGATTGTGAACCGTTTCGCACGCTCACCGGAACTACTGGTAACATTTGCGCTCGGATGGGCGGCGCTTCTGGCCTCT
GCAGGTGATTTTTTCGGATTCAGCAAGGAACTCGGAGGACTGCTTGCCGGCGTCTCACTTGCATCGACACCATTCAGGGA
ATCGATCGTCTCAAGAATGTCATCCCTGCGCGATTTCCTGCTGCTGTTCTTTTTCATATCGCTCGGCATGAACCTTGATT
TAAGCCTTCTTGGCTCCCAGGTCGGCCCGGCCATTATCTTCTCACTGTTTGTTCTGATAGGCAACCCGCTGATCGTCATG
ATCATCATGGGAGTTCTGGGATACCGCAAACGAACCAGCTTTCTGGCCGGCCTGACCGTCGCACAGATCAGCGAATTTTC
TCTGATATTCATGGCAATGGGCATGGATCTCGGGCATGTTGACCCCGAGGCAATGGGACTCGTGACCCTTGTAGGGCTGC
TCACCATAGCGATCTCTGTTTACATGATCACCTACTCCCACACCCTCTACCGCTTCCTTGAACCGCTGCTGGGCGTGTTT
GAAAAAAAGATTCCGTCAAGAGAAATCGAGGCAAACAGTGAACAACTTGAAAACGCTCGCTATGACATCATTCTTTTCGG
GATGGGCAGGTATGGCTCCGCAGTGGCCCACTATCTCAAACAGGACGGATACAGAATTCTTGCAGTCGATTTCAACCCCG
ACGAAATCCGGCAATTAAACAAAAGAGGTTATGACGCTATTTACGGCGACGCAAGCGATCAGGAATTTCTTGCCACCCTG
CCATTGCAGGGTGTGCAATGGGTTGTGTCAGCCGTGTCACAGCACGAACTTGGACTTTCCCGTGAAGACCCCCGAATGGT
CCTGATTGACGCTCTCAAACACACAGGTTTTACAGGCAGAATCGCTGTATCGACCCAACGGATACAGGAAAAAGAAAGAC
TGAAGGCAAAAGGAGCCGATATTGTTTTCCTTCCGTTTTACGATGCCGCCGAACTGGCTGCCAAACGCATCAAAGAAATT
GGCTGA

Upstream 100 bases:

>100_bases
GTTGCTCCAATTATCAGGCAGAAGGCAAACAACAAGGAATCTTTTAACCATGGCTGATATTAAGTAAAGGAATCATGAAG
ACGATCAATATTACTCGCTT

Downstream 100 bases:

>100_bases
TAAATTATCCTGAAAAAAACATGCCTAACTTCAGAAACATCCTTTACATCTCATCCGGCAACGATGAGCACCAAAGCCCC
GGTTTTCGCAAAGCAGTTGA

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MFDLSFIHTVPFYEITALLVLAAITGSLSLLLRQPLIVSLIAVGVLAGPSALDIVQSHEYIELMAELGIALLLFLVGLKL
DISLVRSLGLVALATGLGQVLFTSVTGFFIAQALGLDVRTSIYVAVALTFSSTIIIVKLLSDKKEVDSLHGRVALGFLIV
QDLVVVIAMMTLSAFAVSSQSTGEYDGLLQVGSVIVYGGLMLLLVSIFVRFLANPIVNRFARSPELLVTFALGWAALLAS
AGDFFGFSKELGGLLAGVSLASTPFRESIVSRMSSLRDFLLLFFFISLGMNLDLSLLGSQVGPAIIFSLFVLIGNPLIVM
IIMGVLGYRKRTSFLAGLTVAQISEFSLIFMAMGMDLGHVDPEAMGLVTLVGLLTIAISVYMITYSHTLYRFLEPLLGVF
EKKIPSREIEANSEQLENARYDIILFGMGRYGSAVAHYLKQDGYRILAVDFNPDEIRQLNKRGYDAIYGDASDQEFLATL
PLQGVQWVVSAVSQHELGLSREDPRMVLIDALKHTGFTGRIAVSTQRIQEKERLKAKGADIVFLPFYDAAELAAKRIKEI
G

Sequences:

>Translated_561_residues
MFDLSFIHTVPFYEITALLVLAAITGSLSLLLRQPLIVSLIAVGVLAGPSALDIVQSHEYIELMAELGIALLLFLVGLKL
DISLVRSLGLVALATGLGQVLFTSVTGFFIAQALGLDVRTSIYVAVALTFSSTIIIVKLLSDKKEVDSLHGRVALGFLIV
QDLVVVIAMMTLSAFAVSSQSTGEYDGLLQVGSVIVYGGLMLLLVSIFVRFLANPIVNRFARSPELLVTFALGWAALLAS
AGDFFGFSKELGGLLAGVSLASTPFRESIVSRMSSLRDFLLLFFFISLGMNLDLSLLGSQVGPAIIFSLFVLIGNPLIVM
IIMGVLGYRKRTSFLAGLTVAQISEFSLIFMAMGMDLGHVDPEAMGLVTLVGLLTIAISVYMITYSHTLYRFLEPLLGVF
EKKIPSREIEANSEQLENARYDIILFGMGRYGSAVAHYLKQDGYRILAVDFNPDEIRQLNKRGYDAIYGDASDQEFLATL
PLQGVQWVVSAVSQHELGLSREDPRMVLIDALKHTGFTGRIAVSTQRIQEKERLKAKGADIVFLPFYDAAELAAKRIKEI
G
>Mature_561_residues
MFDLSFIHTVPFYEITALLVLAAITGSLSLLLRQPLIVSLIAVGVLAGPSALDIVQSHEYIELMAELGIALLLFLVGLKL
DISLVRSLGLVALATGLGQVLFTSVTGFFIAQALGLDVRTSIYVAVALTFSSTIIIVKLLSDKKEVDSLHGRVALGFLIV
QDLVVVIAMMTLSAFAVSSQSTGEYDGLLQVGSVIVYGGLMLLLVSIFVRFLANPIVNRFARSPELLVTFALGWAALLAS
AGDFFGFSKELGGLLAGVSLASTPFRESIVSRMSSLRDFLLLFFFISLGMNLDLSLLGSQVGPAIIFSLFVLIGNPLIVM
IIMGVLGYRKRTSFLAGLTVAQISEFSLIFMAMGMDLGHVDPEAMGLVTLVGLLTIAISVYMITYSHTLYRFLEPLLGVF
EKKIPSREIEANSEQLENARYDIILFGMGRYGSAVAHYLKQDGYRILAVDFNPDEIRQLNKRGYDAIYGDASDQEFLATL
PLQGVQWVVSAVSQHELGLSREDPRMVLIDALKHTGFTGRIAVSTQRIQEKERLKAKGADIVFLPFYDAAELAAKRIKEI
G

Specific function: Unknown

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=368, Percent_Identity=23.9130434782609, Blast_Score=86, Evalue=9e-17,
Organism=Escherichia coli, GI1786685, Length=496, Percent_Identity=28.0241935483871, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1786232, Length=465, Percent_Identity=26.2365591397849, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789749, Length=528, Percent_Identity=23.6742424242424, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 60997; Mature: 60997

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MFDLSFIHTVPFYEITALLVLAAITGSLSLLLRQPLIVSLIAVGVLAGPSALDIVQSHEY
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IELMAELGIALLLFLVGLKLDISLVRSLGLVALATGLGQVLFTSVTGFFIAQALGLDVRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SIYVAVALTFSSTIIIVKLLSDKKEVDSLHGRVALGFLIVQDLVVVIAMMTLSAFAVSSQ
HHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
STGEYDGLLQVGSVIVYGGLMLLLVSIFVRFLANPIVNRFARSPELLVTFALGWAALLAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
AGDFFGFSKELGGLLAGVSLASTPFRESIVSRMSSLRDFLLLFFFISLGMNLDLSLLGSQ
CHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VGPAIIFSLFVLIGNPLIVMIIMGVLGYRKRTSFLAGLTVAQISEFSLIFMAMGMDLGHV
CCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DPEAMGLVTLVGLLTIAISVYMITYSHTLYRFLEPLLGVFEKKIPSREIEANSEQLENAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCC
YDIILFGMGRYGSAVAHYLKQDGYRILAVDFNPDEIRQLNKRGYDAIYGDASDQEFLATL
EEEEEEECCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEECCCCCCHHHHHC
PLQGVQWVVSAVSQHELGLSREDPRMVLIDALKHTGFTGRIAVSTQRIQEKERLKAKGAD
CCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCC
IVFLPFYDAAELAAKRIKEIG
EEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]