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The map label for this gene is argS

Identifier: 193213680

GI number: 193213680

Start: 2248106

End: 2249761

Strand: Direct

Name: argS

Synonym: Cpar_2046

Alternate gene names: 193213680

Gene position: 2248106-2249761 (Clockwise)

Preceding gene: 193213679

Following gene: 193213690

Centisome position: 98.2

GC content: 60.21

Gene sequence:

>1656_bases
ATGCGAGCCTTTTTCCTCCCCTTCATTCAGGACGCCCTGCACAAAGCGGGCATCGAGACCGACAAGGAGATTCAGATCGA
CAAGCCGAACGACAAGAAGTTCGGCGACTTCTCGACCAACATCGCCTTCCTGCTGGCCAAGGAGGCCCGGAAAAATCCGC
GAGAGTTGGCGACGCAGTTGATCGGCCTGTTCGCCTTTCCGGAAGGCACGGTGACCAAAACCGAGGTGGCGGGGCCGGGC
TTCATCAACTTCCATCTCGCCCCGGCCTTCTTCATGCGCTCGGCTCAGGAAGTCCTGACGCAGGGCGAGAAGTTCGGCTG
CACGGAGTCAGGCAAGGGACAGAAAGCGATTGTCGAGTACGTCAGCGCCAACCCGACCGGGCCGCTCACCATCGGGCGCG
GACGCGGTGGTGTGCTGGGCGACTGCATCGCCAACCTGCTCGAAACGCAGGGCTACGAGGTGACGCGCGAGTACTACTTC
AACGACGCCGGACGCCAGATGCAGATTCTGGCCGAGTCGGTGCGCTACCGCTACCTCGAAAAGTGCGGGCAGACGGTCGA
GTTCCCGGAGACGCACTACCAGGGCGACTACATCGGTGAGATCGCCGGGACGCTCTTCATCGAGCACAGCGACGAACTGG
CCTCATCCGATGAACTTGGCATCTTCAAGGAGACGGCCGAAGCGGTCATCTTCAGCTCCATCCGCAGAACGCTTGAGCGC
ATCGGCATCACGCATGACTCGTTCTTCAACGAGCACACACTCTATCAGTGGAACGAGGGGGAAGCATCCGGCAACCAGAA
GGTGATCGATGCGCTCGAAGCAAAAGACTTCATCGGACGGTATGACGGCGCGACCTGGTTTATGACCACCAAGCTCGGCC
AGGAGAAGGACAAGGTGCTCATCAAATCCTCCGGCGACCCAAGCTACCGCCTGCCCGACATCGCCTACCACGTCACCAAG
TTCGAGCGCGGCTTCGACCTCATGGTGAACGTCTTCGGCGCGGATCACATCGACGAGTATCCCGACGTGCTCGAAGCGCT
GAAAATTCTCGGCTACGACGCCTCCAAGGTCAAGATCGCCATCAACCAGTTCGTCACCACCACCGTCGGTGGCCAGACGG
TCAAGATGTCCACCCGCAAGGGCAACGCCGACCTGCTCGACGACCTCATCGAGGATGTCGGTGCGGACGCCACGCGCCTC
TTCTTCATCATGCGCAGCAAGGATTCGCACCTGAACTTCGATGTCGAGCTGGCTAAAAAGCAGTCGAAAGACAACCCTGT
CTTCTACCTCCAGTACGCCCACGCAAGGATTTGCAGCCTCGTGCGTCTTGCCGAAAAAGAGGTCGGCTTCGACGAAGCTG
CGGCCACTGGCGCTAGCCTGCCGCTGCTCGACAGCGAACCGGAGATCGACCTCGCCTCCGCGCTGCTCGACTTCCCGGAT
GTCATCCAATCCTGCCTGCGCCTGCTCGAACCGCAGAAGATGGTCGAGTACCTGCACACGGTCGCCGAGCGCTACCACAA
GTTCTATCAGGAGTGCCCGATCCTGAAAGCGGACGAAAACATCCGCACGGCGCGGCTTGAGCTGTCACTCACGGTGCGTC
AGGTGCTGCGCAACGGCTTCAGAATTCTGGGAATTTCCGCGCCGGAATCGATGTAA

Upstream 100 bases:

>100_bases
CAACGTCATCACGACCATCGACCATTTCAACGGCCTCCTGCCCGAAACGCTGCTGGAGCTTAGCAGCACCGCTAAAACCA
TGTCTTAACGATCCATACCG

Downstream 100 bases:

>100_bases
GGAGACGGGACGAAAAGGCGGGCTCAGGAACGATAGAGCCCGTGCTCCGCAATGTAGTGGTTGATCGATGGGGGGACAAG
CTGGGAAACCGGCTGCCCGG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MRAFFLPFIQDALHKAGIETDKEIQIDKPNDKKFGDFSTNIAFLLAKEARKNPRELATQLIGLFAFPEGTVTKTEVAGPG
FINFHLAPAFFMRSAQEVLTQGEKFGCTESGKGQKAIVEYVSANPTGPLTIGRGRGGVLGDCIANLLETQGYEVTREYYF
NDAGRQMQILAESVRYRYLEKCGQTVEFPETHYQGDYIGEIAGTLFIEHSDELASSDELGIFKETAEAVIFSSIRRTLER
IGITHDSFFNEHTLYQWNEGEASGNQKVIDALEAKDFIGRYDGATWFMTTKLGQEKDKVLIKSSGDPSYRLPDIAYHVTK
FERGFDLMVNVFGADHIDEYPDVLEALKILGYDASKVKIAINQFVTTTVGGQTVKMSTRKGNADLLDDLIEDVGADATRL
FFIMRSKDSHLNFDVELAKKQSKDNPVFYLQYAHARICSLVRLAEKEVGFDEAAATGASLPLLDSEPEIDLASALLDFPD
VIQSCLRLLEPQKMVEYLHTVAERYHKFYQECPILKADENIRTARLELSLTVRQVLRNGFRILGISAPESM

Sequences:

>Translated_551_residues
MRAFFLPFIQDALHKAGIETDKEIQIDKPNDKKFGDFSTNIAFLLAKEARKNPRELATQLIGLFAFPEGTVTKTEVAGPG
FINFHLAPAFFMRSAQEVLTQGEKFGCTESGKGQKAIVEYVSANPTGPLTIGRGRGGVLGDCIANLLETQGYEVTREYYF
NDAGRQMQILAESVRYRYLEKCGQTVEFPETHYQGDYIGEIAGTLFIEHSDELASSDELGIFKETAEAVIFSSIRRTLER
IGITHDSFFNEHTLYQWNEGEASGNQKVIDALEAKDFIGRYDGATWFMTTKLGQEKDKVLIKSSGDPSYRLPDIAYHVTK
FERGFDLMVNVFGADHIDEYPDVLEALKILGYDASKVKIAINQFVTTTVGGQTVKMSTRKGNADLLDDLIEDVGADATRL
FFIMRSKDSHLNFDVELAKKQSKDNPVFYLQYAHARICSLVRLAEKEVGFDEAAATGASLPLLDSEPEIDLASALLDFPD
VIQSCLRLLEPQKMVEYLHTVAERYHKFYQECPILKADENIRTARLELSLTVRQVLRNGFRILGISAPESM
>Mature_551_residues
MRAFFLPFIQDALHKAGIETDKEIQIDKPNDKKFGDFSTNIAFLLAKEARKNPRELATQLIGLFAFPEGTVTKTEVAGPG
FINFHLAPAFFMRSAQEVLTQGEKFGCTESGKGQKAIVEYVSANPTGPLTIGRGRGGVLGDCIANLLETQGYEVTREYYF
NDAGRQMQILAESVRYRYLEKCGQTVEFPETHYQGDYIGEIAGTLFIEHSDELASSDELGIFKETAEAVIFSSIRRTLER
IGITHDSFFNEHTLYQWNEGEASGNQKVIDALEAKDFIGRYDGATWFMTTKLGQEKDKVLIKSSGDPSYRLPDIAYHVTK
FERGFDLMVNVFGADHIDEYPDVLEALKILGYDASKVKIAINQFVTTTVGGQTVKMSTRKGNADLLDDLIEDVGADATRL
FFIMRSKDSHLNFDVELAKKQSKDNPVFYLQYAHARICSLVRLAEKEVGFDEAAATGASLPLLDSEPEIDLASALLDFPD
VIQSCLRLLEPQKMVEYLHTVAERYHKFYQECPILKADENIRTARLELSLTVRQVLRNGFRILGISAPESM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=581, Percent_Identity=24.7848537005164, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI197100773, Length=560, Percent_Identity=23.0357142857143, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1788184, Length=614, Percent_Identity=25.5700325732899, Blast_Score=141, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320548, Length=574, Percent_Identity=27.7003484320557, Blast_Score=140, Evalue=4e-34,
Organism=Drosophila melanogaster, GI28571570, Length=515, Percent_Identity=22.3300970873786, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_CHLP8 (B3QLU7)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001999633.1
- ProteinModelPortal:   B3QLU7
- GeneID:   6420998
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_2046
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 61730; Mature: 61730

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFFLPFIQDALHKAGIETDKEIQIDKPNDKKFGDFSTNIAFLLAKEARKNPRELATQL
CCEEEHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHEEEHHHHCCHHHHHHHH
IGLFAFPEGTVTKTEVAGPGFINFHLAPAFFMRSAQEVLTQGEKFGCTESGKGQKAIVEY
HHHHCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
VSANPTGPLTIGRGRGGVLGDCIANLLETQGYEVTREYYFNDAGRQMQILAESVRYRYLE
HHCCCCCCEEECCCCCCHHHHHHHHHHHCCCCEEEHHHHHCCCCCHHHHHHHHHHHHHHH
KCGQTVEFPETHYQGDYIGEIAGTLFIEHSDELASSDELGIFKETAEAVIFSSIRRTLER
HHCCCCCCCCCCCCCCHHHHHHHEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
IGITHDSFFNEHTLYQWNEGEASGNQKVIDALEAKDFIGRYDGATWFMTTKLGQEKDKVL
HCCCHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEE
IKSSGDPSYRLPDIAYHVTKFERGFDLMVNVFGADHIDEYPDVLEALKILGYDASKVKIA
EECCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEE
INQFVTTTVGGQTVKMSTRKGNADLLDDLIEDVGADATRLFFIMRSKDSHLNFDVELAKK
EHHHHHEECCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEHHC
QSKDNPVFYLQYAHARICSLVRLAEKEVGFDEAAATGASLPLLDSEPEIDLASALLDFPD
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHCCHH
VIQSCLRLLEPQKMVEYLHTVAERYHKFYQECPILKADENIRTARLELSLTVRQVLRNGF
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEEHHHHHHHHHHCCC
RILGISAPESM
EEEEECCCCCC
>Mature Secondary Structure
MRAFFLPFIQDALHKAGIETDKEIQIDKPNDKKFGDFSTNIAFLLAKEARKNPRELATQL
CCEEEHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHEEEHHHHCCHHHHHHHH
IGLFAFPEGTVTKTEVAGPGFINFHLAPAFFMRSAQEVLTQGEKFGCTESGKGQKAIVEY
HHHHCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
VSANPTGPLTIGRGRGGVLGDCIANLLETQGYEVTREYYFNDAGRQMQILAESVRYRYLE
HHCCCCCCEEECCCCCCHHHHHHHHHHHCCCCEEEHHHHHCCCCCHHHHHHHHHHHHHHH
KCGQTVEFPETHYQGDYIGEIAGTLFIEHSDELASSDELGIFKETAEAVIFSSIRRTLER
HHCCCCCCCCCCCCCCHHHHHHHEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
IGITHDSFFNEHTLYQWNEGEASGNQKVIDALEAKDFIGRYDGATWFMTTKLGQEKDKVL
HCCCHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEE
IKSSGDPSYRLPDIAYHVTKFERGFDLMVNVFGADHIDEYPDVLEALKILGYDASKVKIA
EECCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEE
INQFVTTTVGGQTVKMSTRKGNADLLDDLIEDVGADATRLFFIMRSKDSHLNFDVELAKK
EHHHHHEECCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEHHC
QSKDNPVFYLQYAHARICSLVRLAEKEVGFDEAAATGASLPLLDSEPEIDLASALLDFPD
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHCCHH
VIQSCLRLLEPQKMVEYLHTVAERYHKFYQECPILKADENIRTARLELSLTVRQVLRNGF
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEEHHHHHHHHHHCCC
RILGISAPESM
EEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA