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The map label for this gene is aroB [H]

Identifier: 193213642

GI number: 193213642

Start: 2206269

End: 2207216

Strand: Direct

Name: aroB [H]

Synonym: Cpar_2006

Alternate gene names: 193213642

Gene position: 2206269-2207216 (Clockwise)

Preceding gene: 193213641

Following gene: 193213653

Centisome position: 96.38

GC content: 63.5

Gene sequence:

>948_bases
ATGCCCAACGCAACCGAACGCATCGCCTGCATCGACGTCGGCACCAACACCGCGCTTCTTCTGATCGCCGACCTCGAACC
CGCCACCGGCAAGATCGTGACCGTCGATCACCGCCAGACCATCGTGCGACTTGGCCAGAAGGTCGATGAGCAGCGGCTGA
TCCATTCGGAGGCGCTCGACCGGCTGACCGCCTGCATGACGGAGTACCGGAAGCTGTGCGACGAGCTTGGCGTGCAGCGC
ATCCTCGCCGTCGGCACCAGCGCTTTGCGCGACGCAGCAAACCGTGACGACATCATCGCGGCGGTGAAAAATGCGACCGG
CATCGAAATCAGCTGCATCAGCGGAGAAAAGGAGGCGGCCCTCACCTTCTTCGGCGCGGTGGCCGGGCTGCCGGAGGTAC
CGGAGCCTTTCACGGTGATCGATATCGGCGGTGGCAGCACCGAAATCATCATGGGCACGACAAGCACGGTCGAAGAGGCG
ATCAGCATGAACATCGGTTCGGTGAGGATGACCGAACGCTTCTGCACCGCGCAACCCCCGTCGCCGGAGGAGTTCGAGGC
GGCGCGGCAGGAGATCGACAACCATCTCGCCGCCACGCTGCCGCCCTTTTTCGCGGGCCGCCAGCAGGTGTTCGGTGTTG
CGGGCACATTGACCACTATAGCGCAGGTGTGCTTGGGAGACAAGCAGTTCGACCCGATGCGGGTGCAGGGCTTCAGACTG
GAGTATGATGCGGTGCACGAGCTGCTCGAACGGCTCCGCGCAATGACGCTCGACGAAATCGTGGCGTTCGGCATTCCGGA
GGGACGCGCCGACGTCTTCACAATGGGCGTGCTGATCCTGCACCAGTTCATGCTGATGCTCGGTGTCGGCAGCCTGACAG
TCAGCATCCAGGGACTGCGCTACGGCGTGGCGCAGCAAGAGCTTCAGAAGCTGCGCGACCGGAGCTGA

Upstream 100 bases:

>100_bases
CGAAGACGAGTGGCTGTCAGCATTGATCGAACCAAAAAACTGATATTCACCTATTCGTCCTATAAGTCCTATCTGACCTA
TAAGACCTATTCTTAACACC

Downstream 100 bases:

>100_bases
AGCTCACGGCTTGCGGCACGAAAGCAAGATGAGGCCGCCCAACGCATCCTTCGTGAAAAAGAGATAGCGCTCGCTGCTCT
CGCCGATTTTGTAGCACTTG

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MPNATERIACIDVGTNTALLLIADLEPATGKIVTVDHRQTIVRLGQKVDEQRLIHSEALDRLTACMTEYRKLCDELGVQR
ILAVGTSALRDAANRDDIIAAVKNATGIEISCISGEKEAALTFFGAVAGLPEVPEPFTVIDIGGGSTEIIMGTTSTVEEA
ISMNIGSVRMTERFCTAQPPSPEEFEAARQEIDNHLAATLPPFFAGRQQVFGVAGTLTTIAQVCLGDKQFDPMRVQGFRL
EYDAVHELLERLRAMTLDEIVAFGIPEGRADVFTMGVLILHQFMLMLGVGSLTVSIQGLRYGVAQQELQKLRDRS

Sequences:

>Translated_315_residues
MPNATERIACIDVGTNTALLLIADLEPATGKIVTVDHRQTIVRLGQKVDEQRLIHSEALDRLTACMTEYRKLCDELGVQR
ILAVGTSALRDAANRDDIIAAVKNATGIEISCISGEKEAALTFFGAVAGLPEVPEPFTVIDIGGGSTEIIMGTTSTVEEA
ISMNIGSVRMTERFCTAQPPSPEEFEAARQEIDNHLAATLPPFFAGRQQVFGVAGTLTTIAQVCLGDKQFDPMRVQGFRL
EYDAVHELLERLRAMTLDEIVAFGIPEGRADVFTMGVLILHQFMLMLGVGSLTVSIQGLRYGVAQQELQKLRDRS
>Mature_314_residues
PNATERIACIDVGTNTALLLIADLEPATGKIVTVDHRQTIVRLGQKVDEQRLIHSEALDRLTACMTEYRKLCDELGVQRI
LAVGTSALRDAANRDDIIAAVKNATGIEISCISGEKEAALTFFGAVAGLPEVPEPFTVIDIGGGSTEIIMGTTSTVEEAI
SMNIGSVRMTERFCTAQPPSPEEFEAARQEIDNHLAATLPPFFAGRQQVFGVAGTLTTIAQVCLGDKQFDPMRVQGFRLE
YDAVHELLERLRAMTLDEIVAFGIPEGRADVFTMGVLILHQFMLMLGVGSLTVSIQGLRYGVAQQELQKLRDRS

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=309, Percent_Identity=27.5080906148867, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788848, Length=303, Percent_Identity=26.0726072607261, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 34233; Mature: 34102

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNATERIACIDVGTNTALLLIADLEPATGKIVTVDHRQTIVRLGQKVDEQRLIHSEALD
CCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHH
RLTACMTEYRKLCDELGVQRILAVGTSALRDAANRDDIIAAVKNATGIEISCISGEKEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCEEEEECCCCHHH
LTFFGAVAGLPEVPEPFTVIDIGGGSTEIIMGTTSTVEEAISMNIGSVRMTERFCTAQPP
HHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECHHHHHHHHHCCCCCEEHHHHHHCCCCC
SPEEFEAARQEIDNHLAATLPPFFAGRQQVFGVAGTLTTIAQVCLGDKQFDPMRVQGFRL
CCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
EYDAVHELLERLRAMTLDEIVAFGIPEGRADVFTMGVLILHQFMLMLGVGSLTVSIQGLR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHH
YGVAQQELQKLRDRS
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
PNATERIACIDVGTNTALLLIADLEPATGKIVTVDHRQTIVRLGQKVDEQRLIHSEALD
CCCCCEEEEEEECCCCEEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHH
RLTACMTEYRKLCDELGVQRILAVGTSALRDAANRDDIIAAVKNATGIEISCISGEKEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCEEEEECCCCHHH
LTFFGAVAGLPEVPEPFTVIDIGGGSTEIIMGTTSTVEEAISMNIGSVRMTERFCTAQPP
HHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECHHHHHHHHHCCCCCEEHHHHHHCCCCC
SPEEFEAARQEIDNHLAATLPPFFAGRQQVFGVAGTLTTIAQVCLGDKQFDPMRVQGFRL
CCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
EYDAVHELLERLRAMTLDEIVAFGIPEGRADVFTMGVLILHQFMLMLGVGSLTVSIQGLR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHH
YGVAQQELQKLRDRS
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]