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The map label for this gene is lolC [H]

Identifier: 193212651

GI number: 193212651

Start: 1101888

End: 1103138

Strand: Direct

Name: lolC [H]

Synonym: Cpar_0996

Alternate gene names: 193212651

Gene position: 1101888-1103138 (Clockwise)

Preceding gene: 193212650

Following gene: 193212652

Centisome position: 48.13

GC content: 60.99

Gene sequence:

>1251_bases
ATGAACGCAGGGTTCTGGATAGCGAGTCGTTACAGCTTCGCGCGGAAGCGGTTTCGGGTGATCAACATCATCTCCGGCAT
CAGCCTCGCAGGGATCGTAGTCGGCGTTTCAACGCTGCTGATTGTGATGAGCGTGCTGAACGGGTTCCAGCAGCTCGCAC
GCGACCTGTTCGTGACCGTCGAAAGCCCGGTACAGCTCGTGCCTGCGGAGGGGCGCTCGATGGTGGTTTCCGACTCGCTG
CTGGCGGCTATCGGCAAAATCAATGGCGTGCAGACGGTCGATCCGTTCGTCGAAGGGCAGGCGATTCTTTCCACGCCGGG
CAAGAGCGAACTGGTCATGGTCAAGGGGGTGACGCCGGATGCGCAACGCCGGATGCAAACGGGTACCGGGGTTCGTCCGC
CGCTTTTTTCCGGCGATGGGGTTTCCGTCGGAAGCCTGCTGGCAGAACGCATGGAGCTCTACGCGGGCCAGCGGGTGCGG
CTCTTCAGTCCGGAACTGATTTCGGCGGGCTTGCAGGCGCTCTCGCAGCCGGAGCTGTTGCCCGCGCTTTCGATCGGCGA
GGCGAGAGTCGAGTCGGCGTTCGTCTTGCAGCAGATTTTCGATGACCGCTACGTGCTTGCGCCTCTTTCAGTTGGCCGGA
CGATTCTGCTTTACGGCAAGGAGCGCTATTCCGGCCTCGATGTGCGACCGGAGAGCGGTGTGCGGGCTGACGAGCTTGAA
CGGGAACTTCGCCAGTGGCTTGCGGCGAACGGGCTTGGCGGGAAGTGGACGGTGATGACGCTCGAAGAGAAGCATCGGGA
GCTGTTCGCTGTGATGCGTCTCGAAAAGTGGGCGAGCTTCGCGGTGCTGATGCTGGTGATTATGGTTGCGCTGCTGAGCC
TTGCCGGGTCGCTCGCCATGACGGTGATCGATAAAAAGCACGAACTGTTCTACCTGCGCTGCCTTGGCATGGAGCGCCCG
CAGTTCATGACCATTTTCATCGTGGAAGGAGGCTTGACCGGACTGGTCGGCACGGCGCTCGGTTCGCTGATTGCCTGGCT
TCTCCTTAAAGCGCAGGAGCTGTATGGCTTCGTAAAACTTCCATCGGAAAGCGCCTTCATCATCAAAGCCTACCCCGTCA
GCATGCAGGCATGGGATTTCGTGGCCGTCGGAGCCGCCGCGATGCTCTTTACGCTGCTGGTCAGCCTCTATCCCGCCGGA
AAAGCTGCCGCGATTGCCACGAGCCGGTCGCTGGAAGACAAGAGCGAGTGA

Upstream 100 bases:

>100_bases
GCCGTGGCGCTGCTGACGCTGCTGTTTGCTTTCATTCCATCGCGTGTGGCTGCCTCGCTGCGGCCCAGCACGGCCCTGAC
CGTATGAGGAGCCACGAACG

Downstream 100 bases:

>100_bases
GGGGGGGATGATAAAACAGTCTTTTCTTCAGGAGGGTTTTAACCCGACGGATATTCCAGGTTTTACATTTAATTCCATTT
CTAAAAAAGTATACATCATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MNAGFWIASRYSFARKRFRVINIISGISLAGIVVGVSTLLIVMSVLNGFQQLARDLFVTVESPVQLVPAEGRSMVVSDSL
LAAIGKINGVQTVDPFVEGQAILSTPGKSELVMVKGVTPDAQRRMQTGTGVRPPLFSGDGVSVGSLLAERMELYAGQRVR
LFSPELISAGLQALSQPELLPALSIGEARVESAFVLQQIFDDRYVLAPLSVGRTILLYGKERYSGLDVRPESGVRADELE
RELRQWLAANGLGGKWTVMTLEEKHRELFAVMRLEKWASFAVLMLVIMVALLSLAGSLAMTVIDKKHELFYLRCLGMERP
QFMTIFIVEGGLTGLVGTALGSLIAWLLLKAQELYGFVKLPSESAFIIKAYPVSMQAWDFVAVGAAAMLFTLLVSLYPAG
KAAAIATSRSLEDKSE

Sequences:

>Translated_416_residues
MNAGFWIASRYSFARKRFRVINIISGISLAGIVVGVSTLLIVMSVLNGFQQLARDLFVTVESPVQLVPAEGRSMVVSDSL
LAAIGKINGVQTVDPFVEGQAILSTPGKSELVMVKGVTPDAQRRMQTGTGVRPPLFSGDGVSVGSLLAERMELYAGQRVR
LFSPELISAGLQALSQPELLPALSIGEARVESAFVLQQIFDDRYVLAPLSVGRTILLYGKERYSGLDVRPESGVRADELE
RELRQWLAANGLGGKWTVMTLEEKHRELFAVMRLEKWASFAVLMLVIMVALLSLAGSLAMTVIDKKHELFYLRCLGMERP
QFMTIFIVEGGLTGLVGTALGSLIAWLLLKAQELYGFVKLPSESAFIIKAYPVSMQAWDFVAVGAAAMLFTLLVSLYPAG
KAAAIATSRSLEDKSE
>Mature_416_residues
MNAGFWIASRYSFARKRFRVINIISGISLAGIVVGVSTLLIVMSVLNGFQQLARDLFVTVESPVQLVPAEGRSMVVSDSL
LAAIGKINGVQTVDPFVEGQAILSTPGKSELVMVKGVTPDAQRRMQTGTGVRPPLFSGDGVSVGSLLAERMELYAGQRVR
LFSPELISAGLQALSQPELLPALSIGEARVESAFVLQQIFDDRYVLAPLSVGRTILLYGKERYSGLDVRPESGVRADELE
RELRQWLAANGLGGKWTVMTLEEKHRELFAVMRLEKWASFAVLMLVIMVALLSLAGSLAMTVIDKKHELFYLRCLGMERP
QFMTIFIVEGGLTGLVGTALGSLIAWLLLKAQELYGFVKLPSESAFIIKAYPVSMQAWDFVAVGAAAMLFTLLVSLYPAG
KAAAIATSRSLEDKSE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=432, Percent_Identity=24.3055555555556, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787360, Length=419, Percent_Identity=23.8663484486874, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45221; Mature: 45221

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAGFWIASRYSFARKRFRVINIISGISLAGIVVGVSTLLIVMSVLNGFQQLARDLFVTV
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
ESPVQLVPAEGRSMVVSDSLLAAIGKINGVQTVDPFVEGQAILSTPGKSELVMVKGVTPD
CCCEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCCEEEEECCCCH
AQRRMQTGTGVRPPLFSGDGVSVGSLLAERMELYAGQRVRLFSPELISAGLQALSQPELL
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCC
PALSIGEARVESAFVLQQIFDDRYVLAPLSVGRTILLYGKERYSGLDVRPESGVRADELE
CCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
RELRQWLAANGLGGKWTVMTLEEKHRELFAVMRLEKWASFAVLMLVIMVALLSLAGSLAM
HHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVIDKKHELFYLRCLGMERPQFMTIFIVEGGLTGLVGTALGSLIAWLLLKAQELYGFVKL
HHCCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEC
PSESAFIIKAYPVSMQAWDFVAVGAAAMLFTLLVSLYPAGKAAAIATSRSLEDKSE
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCC
>Mature Secondary Structure
MNAGFWIASRYSFARKRFRVINIISGISLAGIVVGVSTLLIVMSVLNGFQQLARDLFVTV
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
ESPVQLVPAEGRSMVVSDSLLAAIGKINGVQTVDPFVEGQAILSTPGKSELVMVKGVTPD
CCCEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCCEEEEECCCCH
AQRRMQTGTGVRPPLFSGDGVSVGSLLAERMELYAGQRVRLFSPELISAGLQALSQPELL
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCC
PALSIGEARVESAFVLQQIFDDRYVLAPLSVGRTILLYGKERYSGLDVRPESGVRADELE
CCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
RELRQWLAANGLGGKWTVMTLEEKHRELFAVMRLEKWASFAVLMLVIMVALLSLAGSLAM
HHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVIDKKHELFYLRCLGMERPQFMTIFIVEGGLTGLVGTALGSLIAWLLLKAQELYGFVKL
HHCCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEC
PSESAFIIKAYPVSMQAWDFVAVGAAAMLFTLLVSLYPAGKAAAIATSRSLEDKSE
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]