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The map label for this gene is lolC [H]

Identifier: 193212650

GI number: 193212650

Start: 1100594

End: 1101874

Strand: Direct

Name: lolC [H]

Synonym: Cpar_0995

Alternate gene names: 193212650

Gene position: 1100594-1101874 (Clockwise)

Preceding gene: 193212649

Following gene: 193212651

Centisome position: 48.08

GC content: 60.27

Gene sequence:

>1281_bases
GTGAAAGCCGAGTTCTATATTGCCCGTCGATTTGCGTTCAAGCCGCGGTCGCATTCGAAGCCGACCTTTATTGTGTTTGC
TTCAGCGCTGGGCATTGCGGTCGGGACGGCGGCGCTGATTTTGACGTTGTCTATCGTCAACGGGTTTTCATCCGTCATCG
AAGGCAAGCTCATCCGGTTTACGTCGCATCTTCAGGTGCGGCAGGCGGATGGGCGTCTTTTTTACGAGACTCGCCGAGAT
CGCCAGACGTTGAACGGCGTGCCGGGCATTGCTGAAACTTACCCGTTCCTCGAACTGAACGTGATGCTCAAGAGCCGGAA
CCAGTCGCGCGGTGACGGCGGTGGCATTGCGCCCGCGCAGATTCGGGGGATCACGCCGGAGGAGGCCCGGAAATTTCTCG
GCGGTGCAGAGAGCGGTTTGTGGCAGGCGCTGGATGGCACGGATGCAGAGGCAGATGGAGCGCTGCCGGTGATGTGCGGC
AAGGCGCTGGCCGAGCAGCTCGGCATCAAGACCGGCGACCGGCTGATGATTGTGGGTGTCGATGGTGGTGCAAATGGCTC
GGCTCTTTCCGGAGCGCAGAGCGTGGTTGAGCTTTTATCCGGCCTCGATCTGCAGGTGGCCAGAGTTGCGGGCATCTACA
ACACCGGCCTGACCGAGGGGTTCGACGATCTGGTGGTGTTCGCCGGTCTGGGGCGGCTCCAGGCGCTCTACCATCCCGGC
ATGATTTCTGGCTACGAGGCTAACGTCACCGACCTGCGCAACCTCGACGCCATTTCGGCGCAAGTGACCGAGGCGCTCGG
CTATCCCTTTTATTCCTACACGGTTTATCAGCGCTACTCAAACCTCTTCGAGTGGCTGAAGCTCCAGAAGAACATCACAC
CGCTCCTGATCGTGACCATCACGGTGGTGGCGGTGTTCAACATCGTTTCGACGCTGCTGGTGCTCATCATCGAAAAGACG
AAGGAGATCGGGATGCTCTCAGCGCTCGGGCTTGAACCGGGCGGCATCAGCCGGGTGTTCATGGGGCAGGCGCTGATGAT
TGCGCTGGTGGGCATCGGCACGGGTAATCTGCTTGCGCTTGGGCTGTCGCTGTTCGAGCTGCACTTCCACCTCATCAAAC
TTCCTGAGGAGAGCTACTTCGTCAGCCAGGTGCCGATCCAGATCGACCCGATGAACTACCTGCTCGTCTCCGCTGCCGTG
GCGCTGCTGACGCTGCTGTTTGCTTTCATTCCATCGCGTGTGGCTGCCTCGCTGCGGCCCAGCACGGCCCTGACCGTATG
A

Upstream 100 bases:

>100_bases
CTCGCAATCCTGCACCAGCAACCCGGAAATTCTTATCTTTCCCGTCATTAATCTTCAAAGACCCGTTCCCAGAAAGCCAC
CACACGCCCTTATCTACCCA

Downstream 100 bases:

>100_bases
GGAGCCACGAACGATGAACGCAGGGTTCTGGATAGCGAGTCGTTACAGCTTCGCGCGGAAGCGGTTTCGGGTGATCAACA
TCATCTCCGGCATCAGCCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MKAEFYIARRFAFKPRSHSKPTFIVFASALGIAVGTAALILTLSIVNGFSSVIEGKLIRFTSHLQVRQADGRLFYETRRD
RQTLNGVPGIAETYPFLELNVMLKSRNQSRGDGGGIAPAQIRGITPEEARKFLGGAESGLWQALDGTDAEADGALPVMCG
KALAEQLGIKTGDRLMIVGVDGGANGSALSGAQSVVELLSGLDLQVARVAGIYNTGLTEGFDDLVVFAGLGRLQALYHPG
MISGYEANVTDLRNLDAISAQVTEALGYPFYSYTVYQRYSNLFEWLKLQKNITPLLIVTITVVAVFNIVSTLLVLIIEKT
KEIGMLSALGLEPGGISRVFMGQALMIALVGIGTGNLLALGLSLFELHFHLIKLPEESYFVSQVPIQIDPMNYLLVSAAV
ALLTLLFAFIPSRVAASLRPSTALTV

Sequences:

>Translated_426_residues
MKAEFYIARRFAFKPRSHSKPTFIVFASALGIAVGTAALILTLSIVNGFSSVIEGKLIRFTSHLQVRQADGRLFYETRRD
RQTLNGVPGIAETYPFLELNVMLKSRNQSRGDGGGIAPAQIRGITPEEARKFLGGAESGLWQALDGTDAEADGALPVMCG
KALAEQLGIKTGDRLMIVGVDGGANGSALSGAQSVVELLSGLDLQVARVAGIYNTGLTEGFDDLVVFAGLGRLQALYHPG
MISGYEANVTDLRNLDAISAQVTEALGYPFYSYTVYQRYSNLFEWLKLQKNITPLLIVTITVVAVFNIVSTLLVLIIEKT
KEIGMLSALGLEPGGISRVFMGQALMIALVGIGTGNLLALGLSLFELHFHLIKLPEESYFVSQVPIQIDPMNYLLVSAAV
ALLTLLFAFIPSRVAASLRPSTALTV
>Mature_426_residues
MKAEFYIARRFAFKPRSHSKPTFIVFASALGIAVGTAALILTLSIVNGFSSVIEGKLIRFTSHLQVRQADGRLFYETRRD
RQTLNGVPGIAETYPFLELNVMLKSRNQSRGDGGGIAPAQIRGITPEEARKFLGGAESGLWQALDGTDAEADGALPVMCG
KALAEQLGIKTGDRLMIVGVDGGANGSALSGAQSVVELLSGLDLQVARVAGIYNTGLTEGFDDLVVFAGLGRLQALYHPG
MISGYEANVTDLRNLDAISAQVTEALGYPFYSYTVYQRYSNLFEWLKLQKNITPLLIVTITVVAVFNIVSTLLVLIIEKT
KEIGMLSALGLEPGGISRVFMGQALMIALVGIGTGNLLALGLSLFELHFHLIKLPEESYFVSQVPIQIDPMNYLLVSAAV
ALLTLLFAFIPSRVAASLRPSTALTV

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=437, Percent_Identity=24.7139588100687, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787360, Length=408, Percent_Identity=26.9607843137255, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45759; Mature: 45759

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAEFYIARRFAFKPRSHSKPTFIVFASALGIAVGTAALILTLSIVNGFSSVIEGKLIRF
CCCCEEEEEHHEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEE
TSHLQVRQADGRLFYETRRDRQTLNGVPGIAETYPFLELNVMLKSRNQSRGDGGGIAPAQ
HHHEEEEECCCCEEEHHHHHHHHHCCCCCHHHCCCEEEEEEEEECCCCCCCCCCCCCHHH
IRGITPEEARKFLGGAESGLWQALDGTDAEADGALPVMCGKALAEQLGIKTGDRLMIVGV
EECCCHHHHHHHHCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEE
DGGANGSALSGAQSVVELLSGLDLQVARVAGIYNTGLTEGFDDLVVFAGLGRLQALYHPG
CCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
MISGYEANVTDLRNLDAISAQVTEALGYPFYSYTVYQRYSNLFEWLKLQKNITPLLIVTI
CCCCCCCCHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
TVVAVFNIVSTLLVLIIEKTKEIGMLSALGLEPGGISRVFMGQALMIALVGIGTGNLLAL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
GLSLFELHFHLIKLPEESYFVSQVPIQIDPMNYLLVSAAVALLTLLFAFIPSRVAASLRP
HHHHHHHHHHHHCCCCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
STALTV
CCCCCC
>Mature Secondary Structure
MKAEFYIARRFAFKPRSHSKPTFIVFASALGIAVGTAALILTLSIVNGFSSVIEGKLIRF
CCCCEEEEEHHEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEE
TSHLQVRQADGRLFYETRRDRQTLNGVPGIAETYPFLELNVMLKSRNQSRGDGGGIAPAQ
HHHEEEEECCCCEEEHHHHHHHHHCCCCCHHHCCCEEEEEEEEECCCCCCCCCCCCCHHH
IRGITPEEARKFLGGAESGLWQALDGTDAEADGALPVMCGKALAEQLGIKTGDRLMIVGV
EECCCHHHHHHHHCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEE
DGGANGSALSGAQSVVELLSGLDLQVARVAGIYNTGLTEGFDDLVVFAGLGRLQALYHPG
CCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
MISGYEANVTDLRNLDAISAQVTEALGYPFYSYTVYQRYSNLFEWLKLQKNITPLLIVTI
CCCCCCCCHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
TVVAVFNIVSTLLVLIIEKTKEIGMLSALGLEPGGISRVFMGQALMIALVGIGTGNLLAL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
GLSLFELHFHLIKLPEESYFVSQVPIQIDPMNYLLVSAAVALLTLLFAFIPSRVAASLRP
HHHHHHHHHHHHCCCCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
STALTV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]