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The map label for this gene is mepA [H]

Identifier: 193212584

GI number: 193212584

Start: 1014051

End: 1015130

Strand: Direct

Name: mepA [H]

Synonym: Cpar_0925

Alternate gene names: 193212584

Gene position: 1014051-1015130 (Clockwise)

Preceding gene: 193212583

Following gene: 193212585

Centisome position: 44.3

GC content: 61.2

Gene sequence:

>1080_bases
ATGAAGCATCGTAACCGAATCATCGCTGTCGTGCTGCTGCTGGCGGTAGCTGTGTTGGCTTTTCTGGCTTTGAATAAAAA
GCCGAAGCCGACAACCCCATCTTCTGAAAGCGAGCGGGTTTCGGCGATGAGCATCGCCGTGAGCGTCGAACCGGCAACGT
TGGCTTCGGTGCGCGACAGCCTTTCCGTGGTTGCGCTGGTCGATGCGTGGCGGGACGTCGATCTTCACGCTGAGACCTCC
GGTATTGTTCGCAAGGTAAACGTCGAGGTGGGCGAGAGGCTCAAGGCCGGTCAGCCGCTTTTCAATGTCGATGACGAGGT
CGCGGCCTCGGCTCTGCGCAAAGCCCGGGTGAACCGCGAGCTGGCGTACCGCGATTTCGAACGCTACGAGCGGCTTCACA
AGGAAGGCGCGGTGTCTGAATCTAGCTTCGAGGCGATGAGGCTCAAGTTCGCTGACGCGGAAGCCGATCTGGTTGCTGCC
CGCCGCCGTCTTGAGGATACGGCGATCAAAGCGCCGTTTGCGGGCGTCGTTACGTCAAAACTTGTCGAGGTGGGCGACCT
TGTGCAGCCGGGCGCGAAGGTGGCTAACATGGTCGATCTCTCGAAGCTCAAAATTCGCTCTTCGATTCCTGAAAAACAGG
TCTCACTGGTCACCGAGGGTATGCCGGTGCAGATTACGACGGACGTTTGGCCGGGCAAGGTGTTCGAGGCCCGTGTGCTG
TCGGTCAGCGCCAAATCGTCGCGCGATCACACCTACGAAGTAGAGTCGGTCATGCCCAATCCGCTGAAAACCCCGTTCCG
CGCAGGGATGTTTGCCCGCACGGCCTTTGTCGGCAAACAGTCGCGAGAAGCTCTGCTCATCCCGCGTCAGGCGCTTGTCG
GCAGCGCATCCGAGGCCGCGGTGTTCGTTGTTCGCGATGGCAAGGCGAAGCTCACGAAGCTCGTTGCCGGAGCCGAATAC
GGCACGCAGATTGAAGTGGTCCAGGGGCTTGCACCGGGCGACAAGGTGGTGGTGAGCGGCCAGAGCGATCTGGACGACGG
CTCGCCGGTCGCCGTCACCGGTCCGGAGGAGGCGCGGTGA

Upstream 100 bases:

>100_bases
TTGATACGTCATATTATTGGACAAAGTTCTGTTTGAGGACGTGGAGCAAAGTGTTTCGGCATTCTTTGCCTGCTTTGTCC
ACCAAGTCTATTTTTCTCCT

Downstream 100 bases:

>100_bases
ACGGTTCCCTGACTGCGCTCGCCATCCGGCGTCCGACGCTGGTGGCGGTGTTGTTTTCGGTGATCGCCATTCTCGGCTTC
TTCAGCTACCGGCAGCTCCA

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKHRNRIIAVVLLLAVAVLAFLALNKKPKPTTPSSESERVSAMSIAVSVEPATLASVRDSLSVVALVDAWRDVDLHAETS
GIVRKVNVEVGERLKAGQPLFNVDDEVAASALRKARVNRELAYRDFERYERLHKEGAVSESSFEAMRLKFADAEADLVAA
RRRLEDTAIKAPFAGVVTSKLVEVGDLVQPGAKVANMVDLSKLKIRSSIPEKQVSLVTEGMPVQITTDVWPGKVFEARVL
SVSAKSSRDHTYEVESVMPNPLKTPFRAGMFARTAFVGKQSREALLIPRQALVGSASEAAVFVVRDGKAKLTKLVAGAEY
GTQIEVVQGLAPGDKVVVSGQSDLDDGSPVAVTGPEEAR

Sequences:

>Translated_359_residues
MKHRNRIIAVVLLLAVAVLAFLALNKKPKPTTPSSESERVSAMSIAVSVEPATLASVRDSLSVVALVDAWRDVDLHAETS
GIVRKVNVEVGERLKAGQPLFNVDDEVAASALRKARVNRELAYRDFERYERLHKEGAVSESSFEAMRLKFADAEADLVAA
RRRLEDTAIKAPFAGVVTSKLVEVGDLVQPGAKVANMVDLSKLKIRSSIPEKQVSLVTEGMPVQITTDVWPGKVFEARVL
SVSAKSSRDHTYEVESVMPNPLKTPFRAGMFARTAFVGKQSREALLIPRQALVGSASEAAVFVVRDGKAKLTKLVAGAEY
GTQIEVVQGLAPGDKVVVSGQSDLDDGSPVAVTGPEEAR
>Mature_359_residues
MKHRNRIIAVVLLLAVAVLAFLALNKKPKPTTPSSESERVSAMSIAVSVEPATLASVRDSLSVVALVDAWRDVDLHAETS
GIVRKVNVEVGERLKAGQPLFNVDDEVAASALRKARVNRELAYRDFERYERLHKEGAVSESSFEAMRLKFADAEADLVAA
RRRLEDTAIKAPFAGVVTSKLVEVGDLVQPGAKVANMVDLSKLKIRSSIPEKQVSLVTEGMPVQITTDVWPGKVFEARVL
SVSAKSSRDHTYEVESVMPNPLKTPFRAGMFARTAFVGKQSREALLIPRQALVGSASEAAVFVVRDGKAKLTKLVAGAEY
GTQIEVVQGLAPGDKVVVSGQSDLDDGSPVAVTGPEEAR

Specific function: The periplasmic linker protein component of an organic solvent and antibiotic efflux pump; confers resistance to toluene, hexane, p-xylene, ampicillin, penicillin G, erythromycin, novobiocin and tetracycline [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081796, Length=369, Percent_Identity=26.0162601626016, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789929, Length=303, Percent_Identity=26.4026402640264, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38663; Mature: 38663

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHRNRIIAVVLLLAVAVLAFLALNKKPKPTTPSSESERVSAMSIAVSVEPATLASVRDS
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEEEEEEEECCHHHHHHHHH
LSVVALVDAWRDVDLHAETSGIVRKVNVEVGERLKAGQPLFNVDDEVAASALRKARVNRE
HHEEEEEHHHCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LAYRDFERYERLHKEGAVSESSFEAMRLKFADAEADLVAARRRLEDTAIKAPFAGVVTSK
HHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
LVEVGDLVQPGAKVANMVDLSKLKIRSSIPEKQVSLVTEGMPVQITTDVWPGKVFEARVL
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCCHHEEEEE
SVSAKSSRDHTYEVESVMPNPLKTPFRAGMFARTAFVGKQSREALLIPRQALVGSASEAA
EEECCCCCCCEEEHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHCCCCCCE
VFVVRDGKAKLTKLVAGAEYGTQIEVVQGLAPGDKVVVSGQSDLDDGSPVAVTGPEEAR
EEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MKHRNRIIAVVLLLAVAVLAFLALNKKPKPTTPSSESERVSAMSIAVSVEPATLASVRDS
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEEEEEEEECCHHHHHHHHH
LSVVALVDAWRDVDLHAETSGIVRKVNVEVGERLKAGQPLFNVDDEVAASALRKARVNRE
HHEEEEEHHHCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LAYRDFERYERLHKEGAVSESSFEAMRLKFADAEADLVAARRRLEDTAIKAPFAGVVTSK
HHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
LVEVGDLVQPGAKVANMVDLSKLKIRSSIPEKQVSLVTEGMPVQITTDVWPGKVFEARVL
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCCHHEEEEE
SVSAKSSRDHTYEVESVMPNPLKTPFRAGMFARTAFVGKQSREALLIPRQALVGSASEAA
EEECCCCCCCEEEHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHCCCCCCE
VFVVRDGKAKLTKLVAGAEYGTQIEVVQGLAPGDKVVVSGQSDLDDGSPVAVTGPEEAR
EEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9827328 [H]