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The map label for this gene is cyoB [H]

Identifier: 193212538

GI number: 193212538

Start: 960388

End: 962379

Strand: Direct

Name: cyoB [H]

Synonym: Cpar_0878

Alternate gene names: 193212538

Gene position: 960388-962379 (Clockwise)

Preceding gene: 193212537

Following gene: 193212539

Centisome position: 41.95

GC content: 54.77

Gene sequence:

>1992_bases
ATGCTTGGCAAACTATCGCTCTCCGACATACCGCTCAATGACGCCATCATCATGAACGCGGTTTATGGCTCTCTGGTGCT
GGCGGCTGTCATTATCGGACTGCTCACCTGGTTCAGGAAGTGGTCATTTTTGTGGAACGAATGGCTCACCAGCCTCGACC
ACAAGAAAATCGGCATCATGTACATTGTTCTCGCGAGCGTGATGCTGGTACGCGGATTTTCGGATGCCATGCTCATGCGT
TTGCAACAAGCTATGGCGGCGGGCGCGAACCCGGGATTCCTGCCGCCGCCCCACTTCGACCAGATTTTCGGCTCGCACGG
CACCATCATGATTGTGTTCGTGCTGATGCCCTTTTTGACCGGACTGATGAACATCGTCATCCCCCAGCAGATCGGCGCGC
GTGATGTCGCTTTTCCGCTCATGAACTCCATAAGCCTCGGCTTGACCATAGCGGGCGCATTCCTCGTCATGATTTCACTC
GGCGTCGGCCAGTTCACCACCGCGGGCTGGTCGGGCATCGCGCCTCTTTTCGAGAAGCAATTCAACCCCGGCACGGGCGT
CGATTATTGGATGTGGGCGCTGCAAATCTCCGGCGTAGGCTCCACCCTGACGGGTATCAACTTCCTGGTGACGATCATAA
AAATGCGCGCTCCGGGCCTCACTTTCATGCGCCTGCCGCTTTTCGTCTGGACCGCGCTGACCACCAATGTTCTCATGATT
TTGTCGTTCCCTGTGCTGACAGCCGCCCTTTTCCTTCTGGCTCTGGATCGTTACCTCGGCATGCATTTCTACACCAATGA
TCTGGGCGGAAATATGATGTTGTGGAACAACCTTTTCTGGATGTGGGGCCATCCGGAGGTCTATATCCTCATTCTCCCGG
CCTTCGGAGTTTTTTCCGAAGTGGTGGCGACCTTCTCCAGAAAAAAACTGTTTGGCTACAAATCGCTGGTCTATGCCACG
GTTGCCATCATGTTCCTCTCCTTCACGGTCTGGCTTCATCACTTCTTTACGATGGGCAATACTCCAGAAGTCAACGTCTT
CTTCGGAATTACCACCATGCTGATCGCCATTCCGACCGGCGTCAAGGTGTACGACTGGCTGTTTACGATGTACCGCGGGC
GGATTACCTTCAGCGTGCCGATGTACTGGACGATGGGCTTTCTGACGATCTTCGTGCTTGGTGGCATGACCGGCGTGCTG
TTGTCGATCCCGCCCGCCGATTTCGTGTTCCACAACAGCGTTTTTCTGATTGCGCACTTCCACAACATGCTTATTCCCGG
CGCACTGTTCGGCTATTTCGCGGGCATTCAGTACTGGTTCCCCAAAGCATTCGGGTTCCGCTTGGATGAAAAATGGGGAA
AGCGTGCTTTCTGGGGCTGGTTTATCGGTTTTTTAGTCGCTTTTATGCCGCTCTATATCCTCGGGTTCATGGGAATGCCT
CGGCGCATGTCTCACTACTCCAACCTGGCCTGGCACCCGTTGCTGATTGTAGCGCTCGCTGGCGCAGTGTTCATTGCATT
TGGCATCCTCTCTCTGATAATCCAGTTCATCGTCAGCATCAAAAACCGGAAAGACAATGTTGATGTAACCGGAGACCCGT
GGGGCGGACGTACGCTGGAGTGGGCAACATCCTCGCCACCAGCCGAATATAACTTTGCCGTTATTCCGACAGTCCAGAAC
ATCGACGACTTCTGGGACAGAAAAGAGCGCGGCGTCGCCTACCAGCGACCCGAAAAGTATCATGACATTCGTATGCCGAA
AAACCGCCCGCATGGCGTGATTATCTGCGCATTGGCCCTCACCTTCGGCTTTGCGATGGTCTGGTACATCTGGTGGCTGG
CCGCGTTGAGCATGGCTGGCATCATCGGCACCGTCATCATGAGCGCCGTCACAGACGACACGGAATATGTGATCCCCGCG
CACGAAGTGCAGCGCATCGAAGAGGAACGATTCCGGGCTTTGGCCGCAGCGCAAGATTCAGGGAATAGTTGA

Upstream 100 bases:

>100_bases
GGTTTGTTCGACCACATCGTCGGTCAATTTACCGGCTGGATGGGCGCGGATGGCGCGATGAAATCAATGACGCAACCCAA
CGGAAAGGCGCATGAATAAT

Downstream 100 bases:

>100_bases
TAAAACGGAGCGTTCAATGCAAAACAGTATGGATTCAACATATCTGGCAGAGTGGAAAGAACCCGACCGTCTCGACATGC
AGATGCTCGGTTTCTGGATT

Product: cytochrome o ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MLGKLSLSDIPLNDAIIMNAVYGSLVLAAVIIGLLTWFRKWSFLWNEWLTSLDHKKIGIMYIVLASVMLVRGFSDAMLMR
LQQAMAAGANPGFLPPPHFDQIFGSHGTIMIVFVLMPFLTGLMNIVIPQQIGARDVAFPLMNSISLGLTIAGAFLVMISL
GVGQFTTAGWSGIAPLFEKQFNPGTGVDYWMWALQISGVGSTLTGINFLVTIIKMRAPGLTFMRLPLFVWTALTTNVLMI
LSFPVLTAALFLLALDRYLGMHFYTNDLGGNMMLWNNLFWMWGHPEVYILILPAFGVFSEVVATFSRKKLFGYKSLVYAT
VAIMFLSFTVWLHHFFTMGNTPEVNVFFGITTMLIAIPTGVKVYDWLFTMYRGRITFSVPMYWTMGFLTIFVLGGMTGVL
LSIPPADFVFHNSVFLIAHFHNMLIPGALFGYFAGIQYWFPKAFGFRLDEKWGKRAFWGWFIGFLVAFMPLYILGFMGMP
RRMSHYSNLAWHPLLIVALAGAVFIAFGILSLIIQFIVSIKNRKDNVDVTGDPWGGRTLEWATSSPPAEYNFAVIPTVQN
IDDFWDRKERGVAYQRPEKYHDIRMPKNRPHGVIICALALTFGFAMVWYIWWLAALSMAGIIGTVIMSAVTDDTEYVIPA
HEVQRIEEERFRALAAAQDSGNS

Sequences:

>Translated_663_residues
MLGKLSLSDIPLNDAIIMNAVYGSLVLAAVIIGLLTWFRKWSFLWNEWLTSLDHKKIGIMYIVLASVMLVRGFSDAMLMR
LQQAMAAGANPGFLPPPHFDQIFGSHGTIMIVFVLMPFLTGLMNIVIPQQIGARDVAFPLMNSISLGLTIAGAFLVMISL
GVGQFTTAGWSGIAPLFEKQFNPGTGVDYWMWALQISGVGSTLTGINFLVTIIKMRAPGLTFMRLPLFVWTALTTNVLMI
LSFPVLTAALFLLALDRYLGMHFYTNDLGGNMMLWNNLFWMWGHPEVYILILPAFGVFSEVVATFSRKKLFGYKSLVYAT
VAIMFLSFTVWLHHFFTMGNTPEVNVFFGITTMLIAIPTGVKVYDWLFTMYRGRITFSVPMYWTMGFLTIFVLGGMTGVL
LSIPPADFVFHNSVFLIAHFHNMLIPGALFGYFAGIQYWFPKAFGFRLDEKWGKRAFWGWFIGFLVAFMPLYILGFMGMP
RRMSHYSNLAWHPLLIVALAGAVFIAFGILSLIIQFIVSIKNRKDNVDVTGDPWGGRTLEWATSSPPAEYNFAVIPTVQN
IDDFWDRKERGVAYQRPEKYHDIRMPKNRPHGVIICALALTFGFAMVWYIWWLAALSMAGIIGTVIMSAVTDDTEYVIPA
HEVQRIEEERFRALAAAQDSGNS
>Mature_663_residues
MLGKLSLSDIPLNDAIIMNAVYGSLVLAAVIIGLLTWFRKWSFLWNEWLTSLDHKKIGIMYIVLASVMLVRGFSDAMLMR
LQQAMAAGANPGFLPPPHFDQIFGSHGTIMIVFVLMPFLTGLMNIVIPQQIGARDVAFPLMNSISLGLTIAGAFLVMISL
GVGQFTTAGWSGIAPLFEKQFNPGTGVDYWMWALQISGVGSTLTGINFLVTIIKMRAPGLTFMRLPLFVWTALTTNVLMI
LSFPVLTAALFLLALDRYLGMHFYTNDLGGNMMLWNNLFWMWGHPEVYILILPAFGVFSEVVATFSRKKLFGYKSLVYAT
VAIMFLSFTVWLHHFFTMGNTPEVNVFFGITTMLIAIPTGVKVYDWLFTMYRGRITFSVPMYWTMGFLTIFVLGGMTGVL
LSIPPADFVFHNSVFLIAHFHNMLIPGALFGYFAGIQYWFPKAFGFRLDEKWGKRAFWGWFIGFLVAFMPLYILGFMGMP
RRMSHYSNLAWHPLLIVALAGAVFIAFGILSLIIQFIVSIKNRKDNVDVTGDPWGGRTLEWATSSPPAEYNFAVIPTVQN
IDDFWDRKERGVAYQRPEKYHDIRMPKNRPHGVIICALALTFGFAMVWYIWWLAALSMAGIIGTVIMSAVTDDTEYVIPA
HEVQRIEEERFRALAAAQDSGNS

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=510, Percent_Identity=38.4313725490196, Blast_Score=300, Evalue=3e-81,
Organism=Escherichia coli, GI1786634, Length=663, Percent_Identity=60.1809954751131, Blast_Score=853, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=538, Percent_Identity=36.9888475836431, Blast_Score=310, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=39.3188854489164, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6226523, Length=246, Percent_Identity=32.9268292682927, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74569; Mature: 74569

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50855 COX1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure
MLGKLSLSDIPLNDAIIMNAVYGSLVLAAVIIGLLTWFRKWSFLWNEWLTSLDHKKIGIM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
YIVLASVMLVRGFSDAMLMRLQQAMAAGANPGFLPPPHFDQIFGSHGTIMIVFVLMPFLT
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHH
GLMNIVIPQQIGARDVAFPLMNSISLGLTIAGAFLVMISLGVGQFTTAGWSGIAPLFEKQ
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHC
FNPGTGVDYWMWALQISGVGSTLTGINFLVTIIKMRAPGLTFMRLPLFVWTALTTNVLMI
CCCCCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LSFPVLTAALFLLALDRYLGMHFYTNDLGGNMMLWNNLFWMWGHPEVYILILPAFGVFSE
HHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCEEEEECCCCEEEEEECHHHHHHH
VVATFSRKKLFGYKSLVYATVAIMFLSFTVWLHHFFTMGNTPEVNVFFGITTMLIAIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCC
VKVYDWLFTMYRGRITFSVPMYWTMGFLTIFVLGGMTGVLLSIPPADFVFHNSVFLIAHF
CHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHCHHHHEEECCCHHHHHCCCEEEEEHH
HNMLIPGALFGYFAGIQYWFPKAFGFRLDEKWGKRAFWGWFIGFLVAFMPLYILGFMGMP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
RRMSHYSNLAWHPLLIVALAGAVFIAFGILSLIIQFIVSIKNRKDNVDVTGDPWGGRTLE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
WATSSPPAEYNFAVIPTVQNIDDFWDRKERGVAYQRPEKYHDIRMPKNRPHGVIICALAL
ECCCCCCCCCCEEEECCHHCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHH
TFGFAMVWYIWWLAALSMAGIIGTVIMSAVTDDTEYVIPAHEVQRIEEERFRALAAAQDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHCCC
GNS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]