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The map label for this gene is trxB [H]

Identifier: 193212529

GI number: 193212529

Start: 951054

End: 951989

Strand: Direct

Name: trxB [H]

Synonym: Cpar_0869

Alternate gene names: 193212529

Gene position: 951054-951989 (Clockwise)

Preceding gene: 193212528

Following gene: 193212532

Centisome position: 41.54

GC content: 58.87

Gene sequence:

>936_bases
ATGGATAAAGACATCAGGGACGTCGTCATCATCGGAACCGGCCCTGCCGGATACACTGCGGCCATTTATACCGGAAGAGC
CAACCTCAAGCCGCTGGTTATCGAAGGCCACCAGCCCGGCGGTCAGCTCATGATTACCACCGACATCGAGAACTTTCCCG
GTTTCCCGGAAGGCATTCCCGGTCCGGAGTTGATGGGCAGAATGCGTGAGCAGGCTGCGCGCTTCGGTGTCGAATTCAAG
TTCGGCAGTGTTACCGAGGCCGATGTTTCGCGCAGTCCGTTCAGCCTTACGCTCGATGACGGCAGCGAAATTCTTGCCAG
GACGATCATCATCGCGACCGGTGCCAACGCCAAGTGGCTCGGCATCGAGTCCGAAGAGACCTACCGCGGACGCGGCGTAT
CGGCCTGCGCGACCTGTGACGGCTTTTTCTTCCGCAACTGCCGCGTGTTCGTTGTCGGTGGCGGCGATACGGCGATGGAA
GAGGCGCTCTACCTGACCAAGTTCGCTTCGGAAGTGGTACTGGTGCATCGCCGCGAAGAGTTCCGTGCTTCCAAGATCAT
GAGCCTTCGCGCCAGTAAGAACGAGAAGATCACCACCATGCTCAACGAGGTGGTCGATGAAATTCTCGGTGACGGCATGA
AGGTGACCGGCATTCGTCTCAAGAACGTCAAGACCGGCGAACTGACCGAGCACGCCTGCGACGGCGTTTTTGTCGCCATC
GGCCACGAGCCGAACGCAAAGCTCTTCCAAGGCCAGCTCGACATGGACGATTACGGTTATATCCTGACCAAACCGCACTC
GACTGAAACCAGCGTCAAGGGTGTCTTCGCCTGTGGCGACGTGCAGGACTTCACCTATCGCCAGGCGGTGACGGCTGTCG
GCACCGGTTGCATGTCGGCGATCGAAGCCGAGCGTTTCCTGGAGTCGATCAGGTAA

Upstream 100 bases:

>100_bases
TCGCCTGATTTTCCTTCCGTTTTTTTCTTCAACTATCCCGGCTTCATGCCGGGATAGTTATATCTAAGCATACCCCAACA
CATCTTCCCGGAGATCAACG

Downstream 100 bases:

>100_bases
CGGTCAAACTTGCTGCTTTTTGAAAGGCACCGGGGCTGTTGAGGTTCTGGTGCCTTTTTGCGTTGGGGTGGAATGGACGA
GAAGGGCAACCGCAAGGGTT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MDKDIRDVVIIGTGPAGYTAAIYTGRANLKPLVIEGHQPGGQLMITTDIENFPGFPEGIPGPELMGRMREQAARFGVEFK
FGSVTEADVSRSPFSLTLDDGSEILARTIIIATGANAKWLGIESEETYRGRGVSACATCDGFFFRNCRVFVVGGGDTAME
EALYLTKFASEVVLVHRREEFRASKIMSLRASKNEKITTMLNEVVDEILGDGMKVTGIRLKNVKTGELTEHACDGVFVAI
GHEPNAKLFQGQLDMDDYGYILTKPHSTETSVKGVFACGDVQDFTYRQAVTAVGTGCMSAIEAERFLESIR

Sequences:

>Translated_311_residues
MDKDIRDVVIIGTGPAGYTAAIYTGRANLKPLVIEGHQPGGQLMITTDIENFPGFPEGIPGPELMGRMREQAARFGVEFK
FGSVTEADVSRSPFSLTLDDGSEILARTIIIATGANAKWLGIESEETYRGRGVSACATCDGFFFRNCRVFVVGGGDTAME
EALYLTKFASEVVLVHRREEFRASKIMSLRASKNEKITTMLNEVVDEILGDGMKVTGIRLKNVKTGELTEHACDGVFVAI
GHEPNAKLFQGQLDMDDYGYILTKPHSTETSVKGVFACGDVQDFTYRQAVTAVGTGCMSAIEAERFLESIR
>Mature_311_residues
MDKDIRDVVIIGTGPAGYTAAIYTGRANLKPLVIEGHQPGGQLMITTDIENFPGFPEGIPGPELMGRMREQAARFGVEFK
FGSVTEADVSRSPFSLTLDDGSEILARTIIIATGANAKWLGIESEETYRGRGVSACATCDGFFFRNCRVFVVGGGDTAME
EALYLTKFASEVVLVHRREEFRASKIMSLRASKNEKITTMLNEVVDEILGDGMKVTGIRLKNVKTGELTEHACDGVFVAI
GHEPNAKLFQGQLDMDDYGYILTKPHSTETSVKGVFACGDVQDFTYRQAVTAVGTGCMSAIEAERFLESIR

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=50.4823151125402, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI87081763, Length=311, Percent_Identity=33.1189710610932, Blast_Score=152, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=50.1597444089457, Blast_Score=308, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6321898, Length=312, Percent_Identity=48.7179487179487, Blast_Score=292, Evalue=4e-80,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33861; Mature: 33861

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKDIRDVVIIGTGPAGYTAAIYTGRANLKPLVIEGHQPGGQLMITTDIENFPGFPEGIP
CCCCCCEEEEEECCCCCCEEEEEECCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCC
GPELMGRMREQAARFGVEFKFGSVTEADVSRSPFSLTLDDGSEILARTIIIATGANAKWL
CHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCHHEEEEEEEEEECCCEEEE
GIESEETYRGRGVSACATCDGFFFRNCRVFVVGGGDTAMEEALYLTKFASEVVLVHRREE
ECCCCCCCCCCCCEEEECCCCEEECCEEEEEEECCCHHHHHHHHHHHHHHHHEEEECHHH
FRASKIMSLRASKNEKITTMLNEVVDEILGDGMKVTGIRLKNVKTGELTEHACDGVFVAI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHCCCCEEEEE
GHEPNAKLFQGQLDMDDYGYILTKPHSTETSVKGVFACGDVQDFTYRQAVTAVGTGCMSA
CCCCCCCEEECCCCCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
IEAERFLESIR
HHHHHHHHHCC
>Mature Secondary Structure
MDKDIRDVVIIGTGPAGYTAAIYTGRANLKPLVIEGHQPGGQLMITTDIENFPGFPEGIP
CCCCCCEEEEEECCCCCCEEEEEECCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCC
GPELMGRMREQAARFGVEFKFGSVTEADVSRSPFSLTLDDGSEILARTIIIATGANAKWL
CHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCHHEEEEEEEEEECCCEEEE
GIESEETYRGRGVSACATCDGFFFRNCRVFVVGGGDTAMEEALYLTKFASEVVLVHRREE
ECCCCCCCCCCCCEEEECCCCEEECCEEEEEEECCCHHHHHHHHHHHHHHHHEEEECHHH
FRASKIMSLRASKNEKITTMLNEVVDEILGDGMKVTGIRLKNVKTGELTEHACDGVFVAI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHCCCCEEEEE
GHEPNAKLFQGQLDMDDYGYILTKPHSTETSVKGVFACGDVQDFTYRQAVTAVGTGCMSA
CCCCCCCEEECCCCCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
IEAERFLESIR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]